Data set | Procedure | What's in this data set | Panel | Sex | Age (weeks) | Year |
---|---|---|---|---|---|---|
|
study archive
with methacholine |
Lung, respiratory function, baseline and methacholine-challenged (several doses). | QTL population | f | 7-8wks | 2005 |
|
body size and weight | Body weight, body length, body mass index. Aging study, 6mo, 12mo, 20mo. | inbred (32) | both | 26, 52, 87 wks | 2008 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content, body area, bone area. Aging study, 6mo, 12mo, 20mo. | inbred (32) | both | 26, 52, 87 wks | 2008 |
|
lipid profile
with high-fat diet |
Cholesterol, HDL, non-HDL, triglycerides, phospholipids. 4h fast, plasma. Baseline vs. high-fat diet (6wks). | inbred (15) | both | 6-14wks | 1999 |
|
protein activity assessment
with high-fat diet |
Phospholipid transfer protein activity. 4h fast. | inbred (15) | both | 6-14wks | 1999 |
|
study archive | Body, organ, fat pad weights, weight gain, litter size. | QTL population | both | 2-10wks | 2009 |
|
body weight
with high-fat high-sucrose diet |
Weekly. | DO population | both | 4-26wks | 2018 |
|
intake monitoring
with high-fat high-sucrose diet |
Food intake. Weekly. | DO population | both | 4-26wks | 2018 |
|
metabolic panel
with high-fat high-sucrose diet |
Glucose, HOMA-IR, HOMA-B. | DO population | both | 4-26wks | 2018 |
|
hormone quantification
with high-fat high-sucrose diet |
Plasma insulin, adiponectin, leptin. Ex vivo insulin secretion. | DO population | both | 4-26wks | 2018 |
|
lipid profile
with high-fat high-sucrose diet |
Triglyceride. | DO population | both | 4-26wks | 2018 |
|
glucose tolerance
with high-fat high-sucrose diet |
Area under curve. | DO population | both | 4-26wks | 2018 |
|
biomarker quantification
with high-fat high-sucrose diet |
Bile acids in feces. | DO population | both | 4-26wks | 2018 |
|
body weight
with high-fat diet |
8-29 wks of age. | BXD w/par (57) | m | 8-29 wks | 2016 |
|
NMR
with high-fat diet |
Body composition. | BXD w/par (57) | m | 8-29 wks | 2016 |
|
intake monitoring
with high-fat diet |
Food intake. | BXD w/par (57) | m | 8-29 wks | 2016 |
|
monitoring system
with high-fat diet |
Oxygen consumption and respiratory exchange ratio (RER); activity. | BXD w/par (57) | m | 8-29 wks | 2016 |
|
glucose tolerance
with high-fat diet |
Glucose post oral gavage: 0, 15, 30, 45, 60, 90, 120, 150, 180 min plus area under curve. | BXD w/par (57) | m | 8-29 wks | 2016 |
|
hormone quantification
with high-fat diet |
Glucose post oral gavage: 0, 15, 30 min plus area under curve. | BXD w/par (57) | m | 8-29 wks | 2016 |
|
body temperature
with high-fat diet |
In cold room: 0, 1, 2, 3, 4, 5, 6 h. | BXD w/par (57) | m | 8-29 wks | 2016 |
|
treadmill endurance test
with high-fat diet |
Distance traveled. | BXD w/par (57) | m | 8-29 wks | 2016 |
|
running wheel monitoring
with high-fat diet |
Distance traveled, speed. | BXD w/par (57) | m | 8-29 wks | 2016 |
|
metabolic panel
with high-fat diet |
Enzymes, bile acid, proteins, creatinine, glucose, iron, lactate. | BXD w/par (57) | m | 8-29 wks | 2016 |
|
lipid profile
with high-fat diet |
Cholesterol, HDL, LDL, free fatty acids, triglyceride. | BXD w/par (57) | m | 8-29 wks | 2016 |
|
cell signaling molecule detection
with high-fat diet |
INF-gamma, interleukins, monocyte chemoattractant, macrophage inflammatory protein, T cell RANTES, TNF-alpha. | BXD w/par (57) | m | 8-29 wks | 2016 |
|
body weight
with high-fat diet |
inbred w/CC8 | both | 8-21 wks | 2021 | |
|
monitoring system
with high-fat diet |
Oxygen consumption, carbon dioxide production, respiratory exchange rate (RER); activity. | inbred w/CC8 | both | 8-21 wks | 2021 |
|
glucose tolerance
with high-fat diet |
Plasma glucose levels: 0, 15, 30, 45, 60, 90, 120, 150, and 180 min, post oral gavage following overnight fast. | inbred w/CC8 | both | 8-21 wks | 2021 |
|
hormone quantification
with high-fat diet |
Insulin levels following glucose post oral gavage: 0, 15, 30 min. | inbred w/CC8 | both | 8-21 wks | 2021 |
|
intake monitoring
with high-fat diet |
Food intake. | inbred w/CC8 | both | 8-21 wks | 2021 |
|
treadmill endurance test
with high-fat diet |
Distance traveled. | inbred w/CC8 | both | 8-21 wks | 2021 |
|
metabolic panel
with high-fat diet |
Enzymes, creatinine, iron, lactate, urea. | inbred w/CC8 | both | 8-21 wks | 2021 |
|
lipid profile
with high-fat diet |
Cholesterol, HDL, LDL, triglycerides, free fatty acids. | inbred w/CC8 | both | 8-21 wks | 2021 |
|
intake monitoring | Water intake. Daily. | inbred (13) | m | 7-8wks | 2011 |
|
bottle choice test | Sodium chloride solution taste threshold. Fluid intake. | inbred (13) | m | 7-8wks | 2011 |
|
body weight | Body weight | inbred (13) | m | 7-8wks | 2011 |
|
study archive | Open field test. Locomotor activity, anxiety-related behavior. | QTL population | both | 8wks | 2008 |
|
study archive | Plasma lipids. Cholesterol, triglycerides. | QTL population | both | 12-14wks | 2013 |
|
study archive | Bone morphology and strength, insulin-like growth factor 1. | QTL population | f | 16wks | 2001 |
|
body weight | Body weight and growth curve from 4wks to 26wks weighed monthly. | ILSXISS (97) | f | 6wks | 2005 |
|
alcohol quantification
with ethanol |
Blood alcohol concentrations after ethanol injection over time, acute functional ethanol tolerance. | ILSXISS w/par (74) | both | 8-14wks | 2007 |
|
body weight | Body weight | both | 8-20wks | 2021 | |
|
MRI | Body composition (lean, fat, water). | both | 8-20wks | 2021 | |
|
metabolic panel | Plasma enzymes, creatinine, glucose, urea, metabolic health score. | both | 8-20wks | 2021 | |
|
lipid profile | Cholesterol, non-esterified fatty acids, triglyceride. | both | 8-20wks | 2021 | |
|
biomarker quantification | TMAO, choline, phosphocholine, glycerophosphocholine, betaine, carnitine. | both | 8-20wks | 2021 | |
|
hormone quantification | Insulin, glucose:insulin ratio. | both | 8-20wks | 2021 | |
|
monitoring system | O2 consumption, CO2 production, RER, heat expenditure, activity. | both | 8-20wks | 2021 | |
|
intake monitoring | Food intake; energy intake; protein, carbohydrate, fat intake. | both | 8-20wks | 2021 | |
|
ventilator
with methacholine |
Airway resistance. Baseline vs. methacholine-challenged (several doses). | inbred (37) | both | 9-12wks | 2010 |
|
plethysmography
with methacholine |
Lung, respiratory function. Baseline vs. methacholine-challenged (several doses). | inbred (29) | both | 9-12wks | 2010 |
|
ventilator
with methacholine |
Lung, respiratory function. Anesthetized forced oscillation. Baseline vs. methacholine-challenged (several doses). | inbred (29) | both | 9-12wks | 2010 |
|
metabolite quantification | Vitamin D concentration (serum). | inbred (18) | m | 11wks | 2011 |
|
intake monitoring
with sucrose |
Food, caloric, water intake. Baseline and with sucrose (several concentrations). 24h test. | inbred (12) | m | 13-17wks | 2006 |
|
open field test | Locomotor activity and exploratory behavior. 5 min test in dark. | inbred (10) | both | 8-14wks | 2000 |
|
fear conditioning test | Contextual fear, cued fear. | inbred (8) | both | 9-20wks | 2001 |
|
monitoring system | Social interaction (study 1 and study 2). | inbred (7) | m | 8-12wks | 2007 |
|
open field test | Locomotor activity, exploratory behavior, habituation scores. 15 min test. | inbred (14) | m | 8-12wks | 2009 |
|
body weight
with influenza A (H5N1) virus |
Influenza A (H5N1) virus (several doses) vs. baseline. | inbred (23) | f | 6-9wks | 2011 |
|
health assessment
with Plasmodium berghei |
Susceptibility, Plasmodium berghei (malaria). Parasitemia in blood and distribution in brain, spleen, lungs, liver. | inbred (31) | both | 8-12wks | 2010 |
|
study archive | Protein tau hyperphosphorylation. | QTL population | f | 3wks | 2003 |
|
body weight
with Theiler's murine encephalomyelitis virus |
Body weight | CC (5) | both | 4wks | 2017 |
|
open field test
with Theiler's murine encephalomyelitis virus |
Locomotor activity, TMEV infection. | CC (5) | both | 4wks | 2017 |
|
gait analysis
with Theiler's murine encephalomyelitis virus |
DigiGait analysis and footprint analysis, TMEV infection. | CC (5) | both | 4wks | 2017 |
|
rotarod
with Theiler's murine encephalomyelitis virus |
Latency to fall from accelerating rotarod, TMEV infection. | CC (5) | both | 4wks | 2017 |
|
study archive | Body, organ weights, litter size, abdominal fat, lipids, insulin, leptin. | QTL population | both | 3-6wks | 2009 |
|
elevated plus maze | Locomotor, exploratory, and anxiety-related behavior. | inbred (14) | both | 10wks | 2004 |
|
elevated zero maze | Locomotor, exploratory, and anxiety-related behavior. | inbred (14) | both | 10wks | 2004 |
|
light-dark box | Anxiety, avoidance behavior. | inbred (14) | both | 10wks | 2004 |
|
open field test | Locomotor, exploratory, and anxiety-related behavior. | inbred (14) | both | 10wks | 2004 |
|
Barnes circular maze | Spatial learning and memory. | inbred (14) | both | 10-18wks | 2004 |
|
Morris water maze | Spatial learning and memory. | inbred (14) | both | 10-18wks | 2004 |
|
rotarod | Latency to fall from accelerating rotarod. 7 day trials. | inbred (14) | both | 10-18wks | 2004 |
|
visual water box | Spatial learning and memory. | inbred (14) | both | 10-18wks | 2004 |
|
olfactory discrimination task | Olfactory-related learning and memory. | inbred (14) | both | 10-18wks | 2004 |
|
complete blood count | Hematology. | inbred (10) | both | 8wks | 2013 |
|
ion transport assessment | Hematology red cell ion content, ion transport. | inbred (10) | both | 8wks | 2013 |
|
monitoring system
with morphine |
Induced respiratory depression, time to recovery (for mice that survived), survival data (for mice that did not survive). | inbred w/CC8 (8) | both | 8-24wks | 2020 |
|
study archive | Femur and vertebra morphology and strength. Monthly body weight 3 - 13 months. | QTL population | f | 14-56wks | 2012 |
|
metabolic panel | Clinical blood chemistry (plasma). 4h fast. | inbred w/CC8 (72) | both | 10-13wks | 2009 |
|
complete blood count | Hematology. | inbred w/CC8 (72) | both | 10-13wks | 2009 |
|
lipid profile | Cholesterol, HDL, triglycerides, free fatty acids. 4h fast, plasma. | inbred w/CC8 (72) | both | 10-13wks | 2009 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density. | inbred w/CC8 (72) | both | 10-13wks | 2009 |
|
body size and weight | Body weight and length. | inbred w/CC8 (72) | both | 10-13wks | 2009 |
|
metabolic panel | Glucose (plasma). 4h fast. | CC diallel w/par (62) | both | 8-16wks | 2012 |
|
lipid profile | Cholesterol, HDL, triglycerides. 4h fast, plasma. | CC diallel w/par (62) | both | 8-16wks | 2012 |
|
complete blood count | Hematology. | CC diallel w/par (62) | both | 8-16wks | 2012 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content, bone area. | CC diallel w/par (62) | both | 8-16wks | 2012 |
|
body weight | Body weight | CC diallel w/par (62) | both | 8-16wks | 2012 |
|
metabolic panel | Clinical blood chemistry. 16h fast. | CC diallel w/par (62) | both | 7-15wks | 2011 |
|
complete blood count | Hematology. | CC diallel w/par (62) | both | 7-15wks | 2011 |
|
open field test | Locomotor activity, exploratory, anxiety-related behavior. 10 min test. | CC diallel w/par (62) | both | 7-15wks | 2011 |
|
light-dark box | Anxiety, avoidance behavior. 10 min test. | CC diallel w/par (62) | both | 7-15wks | 2011 |
|
behavior observation | Wildness scoring. | CC diallel w/par (62) | both | 7-15wks | 2011 |
|
monitoring system | Sleep patterns. Dark period, total, peak activity. Baseline and after sleep deprivation. | CC diallel w/par (62) | both | 7-15wks | 2011 |
|
body size and weight | Body weight, body length, tail length. | CC diallel w/par (62) | both | 7-15wks | 2011 |
|
metabolic panel | Clinical blood chemistry. 16h fast. | CC pre w/par (367) | both | 7-15wks | 2011 |
|
complete blood count | Hematology. | CC pre w/par (367) | both | 7-15wks | 2011 |
|
open field test | Locomotor activity, exploratory, anxiety-related behavior. 10 min test. | CC pre w/par (367) | both | 7-15wks | 2011 |
|
light-dark box | Anxiety, avoidance behavior. 10 min test. | CC pre w/par (367) | both | 7-15wks | 2011 |
|
behavior observation | Wildness scoring. | CC pre w/par (367) | both | 7-15wks | 2011 |
|
monitoring system | Sleep patterns. Dark period, total, peak activity. Baseline and after sleep deprivation. | CC pre w/par (367) | both | 7-15wks | 2011 |
|
body size and weight | Body weight, tail length. | CC pre w/par (367) | both | 7-15wks | 2011 |
|
open field test | Locomotor activity, exploratory, anxiety-related behavior. 20 min test. | DO population w/par (9) | both | 12-16wks | 2013 |
|
visual cliff | Anxiety, avoidance behavior. 20 min test. | DO population w/par (9) | both | 12-16wks | 2013 |
|
light-dark box | Anxiety, avoidance behavior. 20 min test. | DO population w/par (9) | both | 12-16wks | 2013 |
|
tail suspension test | Frequency climbing, time immobile, latency immobile. 5 min test. | DO population w/par (9) | both | 12-16wks | 2013 |
|
body weight | Body weight | DO population w/par (9) | both | 12-16wks | 2013 |
|
study archive
with ethanol |
Sensitivity to ethanol. Baseline and ethanol. | QTL population | both | 9-34wks | 2012 |
|
body weight
with high-fat diet |
Body weight and growth curve from age 1wk to 22wks (pre-wean, post-wean, adult). High-fat diet (17wks) vs. control. | LGXSM w/par (19) | both | 12-16wks | 2004 |
|
glucose tolerance
with high-fat diet |
High-fat diet (17wks) vs. control. 0 to 120 min after 10% glucose i.p. 4h fast. | LGXSM w/par (19) | both | 12-16wks | 2004 |
|
lipid profile
with high-fat diet |
Cholesterol, triglycerides, free fatty acids. High-fat diet (17wks) vs. control. 4h fast, serum. | LGXSM w/par (19) | both | 12-16wks | 2004 |
|
hormone quantification
with high-fat diet |
Insulin, leptin. | LGXSM w/par (19) | both | 12-16wks | 2004 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content, bone area. | F1 8way (63) | both | 7-8wks | 2004 |
|
complete blood count | Hematology. | CC pre w/par (139) | m | 10-14wks | 2012 |
|
hormone quantification
with Staphylococcus aureus |
Interleukin 6 levels (serum) after infection with Staphylococcus aureus. Kidney and peritoneal fluid. | inbred (13) | f | 8wks | 2012 |
|
balance beam
with ethanol |
Ethanol i.p. (several doses) vs. control (saline). Missteps count. 3 beam lengths. | inbred (8) | both | 8wks | 2003 |
|
grid test
with ethanol |
Ethanol injection (several doses) vs. control (saline). Grid habituation, missteps rate. | inbred (8) | both | 8wks | 2003 |
|
body weight
with ethanol |
Body weight | inbred (8) | both | 8wks | 2003 |
|
rotarod
with diazepam |
Latency to fall from 5 rpm rotarod immediately after diazepam injection. | inbred (15) | both | 6-7wks | 1998 |
|
drug and metabolite quantification
with diazepam |
Diazepam (and metabolite) concentration in brain tissue immediately after diazepam injection and rotarod. | inbred (15) | both | 6-7wks | 1998 |
|
monitoring system
with diazepam |
Locomotor activity. Baseline vs. immediately after Diazepam injection (several doses). 15 min test. | inbred (15) | both | 6-7wks | 1998 |
|
body temperature
with diazepam |
Baseline vs. 30 min after diazepam injection (several doses). | inbred (15) | both | 6-7wks | 1998 |
|
rotarod
with ethanol |
Baseline and ethanol i.p. 3 fixed speeds (several doses) and accelerating. | inbred (22) | both | 9-17wks | 2003 |
|
dowel balance test
with ethanol |
Latency to fall 0 min and 30 min post-injection, 2 widths. Ethanol 2 g/kg. | inbred (21) | both | 9-17wks | 2003 |
|
vertical wire mesh
with ethanol |
Latency to fall 30 min post-injection. Ethanol 2 g/kg i.p. | inbred (21) | both | 9-17wks | 2003 |
|
grip strength
with ethanol |
Baseline vs. 30 min after ethanol 2 g/kg i.p. | inbred (21) | both | 9-17wks | 2003 |
|
alcohol quantification
with ethanol |
Blood alcohol concentration after ethanol 2 g/kg i.p., several timepoints. | inbred (21) | both | 9-17wks | 2003 |
|
parallel rod floor test
with ethanol |
Parallel rod balance test, baseline vs. ethanol 2 g/kg i.p.. | inbred (8) | both | 7-14wks | 2005 |
|
body weight
with haloperidol |
Baseline vs. after haloperidol 60d implant. | inbred w/CC8 (27) | m | 9-28wks | 2012 |
|
drug and metabolite quantification
with haloperidol |
Haloperidol concentration (plasma). Baseline vs. during and after haloperidol 60d implant (several timepoints). | inbred w/CC8 (27) | m | 9-28wks | 2012 |
|
inclined screen test
with haloperidol |
Baseline vs. during and after haloperidol 60d implant (several timepoints). | inbred w/CC8 (27) | m | 9-28wks | 2012 |
|
open field test
with haloperidol |
Locomotor activity, exploratory behavior, involuntary movement. Baseline vs. haloperidol 60d implant (several timepoints). 60 min test. | inbred w/CC8 (27) | m | 9-28wks | 2012 |
|
behavior observation
with haloperidol |
Observed involuntary repetitive movement. Baseline vs. during and after haloperidol 60d implant (several timepoints). | inbred w/CC8 (27) | m | 9-28wks | 2012 |
|
body weight | Body weight | BXD w/par (55) | both | 10-16wks | 2018 |
|
open field test | Locomotor activity and exploratory behavior. 20 min test. | BXD w/par (55) | both | 10-16wks | 2018 |
|
radial maze | Spatial learning. | BXD w/par (55) | both | 10-16wks | 2018 |
|
behavior observation | Inter-male agression. | BXD w/par (55) | both | 10-16wks | 2018 |
|
open field test | Locomotor response to novelty, habituation. | CC w/par (18) | both | 10-39wks | 2023 |
|
bottle choice test | Palatable food consumption, preference for Boost solution. | CC w/par (18) | both | 10-39wks | 2023 |
|
operant conditioning chamber | Reversal learning (impulsive action) and delay discounting (impulsive choice). | CC w/par (18) | both | 10-39wks | 2023 |
|
open field test
with cocaine |
Distance traveled, habituation ratio, number of rears, ambulatory time, time in perimeter, corners, and center; cocaine sensitization. | CC w/CC8 (61) | both | 4-25wks | 2021 |
|
light-dark box | Distance traveled, ambulatory time and counts, resting time, stereotypic time and counts, jumping time and counts, vertical time and counts, time in light/dark. | CC w/CC8 (61) | both | 4-25wks | 2021 |
|
hole board test | Number of entries, novel entries, and repeat entries. | CC w/CC8 (61) | both | 4-25wks | 2021 |
|
conditioned place preference test | In novel zone: exploration counts, entrance counts, time spent, activity counts, movement counts. | CC w/CC8 (61) | both | 4-25wks | 2021 |
|
operant conditioning chamber
with cocaine |
Number of infusions, active lever presses, inactive lever presses, intravenous self administration, reversal learning. | CC w/CC8 (61) | both | 4-25wks | 2021 |
|
in vitro assay | Circadian parameters in fibroblast cultures: period, amplitude, phase, damping rate, goodness of fit. | CC w/CC8 (61) | both | 4-25wks | 2021 |
|
body weight | Body weight | inbred (13) | both | 10wks | 2004 |
|
operant conditioning chamber | Sign tracking and goal tracking paradigm with Pavlovian conditioned approach. | inbred (5) | both | 12-20wks | 2015 |
|
open field test
with cocaine |
Locomotor activity and exploratory behavior. 20 min test. | DO population | both | 12-16wks | 2015 |
|
hole board test
with cocaine |
Exploratory behavior. 10 min test. | DO population | both | 12-16wks | 2015 |
|
monitoring system
with cocaine |
Novelty preference test (preference for novel side vs. familiar side). 10 min test. | DO population | both | 12-16wks | 2015 |
|
operant conditioning chamber
with cocaine |
Intravenous self-administration of cocaine via activation of levers. | DO population | both | 12-16wks | 2015 |
|
body weight | Body weight | BXD w/par (66) | both | 10wks | 2010 |
|
urinalysis | Microalbumin, creatinine, ratio. | inbred w/CC7 (34) | m | 10wks | 2012 |
|
urinalysis | Microalbumin, creatinine, ratio. | CC pre w/par (163) | m | 10wks | 2012 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content, craniofacial dimensions. | inbred w/CC7 (30) | both | 15-16wks | 2002 |
|
metabolic panel | Thyroxine (serum). | inbred w/CC7 (30) | both | 15-16wks | 2002 |
|
hormone quantification | Osteocalcin, insulin-like growth factor 1. | inbred w/CC7 (30) | both | 15-16wks | 2002 |
|
DXA | Body mass, fat mass, bone mineral density. | B6.A consomic w/par (23) | both | 24-29wks | 2012 |
|
body weight | Pup body weight at day 3. | inbred (15) | f | 6-8wks | 2010 |
|
body weight | Pup body weight at day 3. | B6.A consomic w/par (22) | f | 6-8wks | 2010 |
|
body weight | Body weight | inbred (10) | both | 16wks | 2004 |
|
open field test | Locomotor activity, anxiety-related behavior, involuntary movement. 10 min test. | B6.A consomic w/par (22) | both | 6-7wks | 2011 |
|
hole board test | Exploratory behavior. 10 min test. | B6.A consomic w/par (22) | both | 6-7wks | 2011 |
|
open field test | Locomotor activity, anxiety-related behavior, involuntary repetitive movement. 10 min test. | B6.PWD consomic w/par (28) | both | 6wks | 2011 |
|
immunoglobulin quantification | Immunoglobulin concentrations (plasma). | B6.A consomic w/par (22) | both | 9wks | 2012 |
|
immunoglobulin quantification | Immunoglobulin concentrations (plasma). | B6.PWD consomic w/par (28) | both | 9wks | 2011 |
|
metabolic panel | Clinical blood chemistry (serum). 4h fast. | B6.PWD consomic w/par (25) | both | 11wks | 2011 |
|
study archive | Urinalysis. Creatinine, microalbumin, body weight. | QTL population | m | 8-10wks | 2008 |
|
study archive | Sterility investigation. Sperm count, testes weight. | QTL population | m | 9wks | 2012 |
|
complete blood count | Hematology. | inbred (8) | both | 12wks | 2007 |
|
lipid profile | Cholesterol, HDL, non-HDL, triglycerides, free fatty acids. Plasma. | inbred (8) | both | 12wks | 2007 |
|
metabolic panel | Clinical blood chemistry (plasma). Unknown fast. | inbred (8) | both | 12wks | 2007 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content. | inbred (5) | both | 12, 24, 52 wks | 2008 |
|
glucose tolerance | 0 to 180 min after 20% glucose i.p. 16h fast. | inbred (4) | both | 12, 24, 52 wks | 2008 |
|
intake monitoring | Food intake. Daily. | inbred (4) | both | 12, 24 wks | 2008 |
|
body temperature | Hourly readings in cold room. 6h test. | inbred (4) | both | 12wks | 2008 |
|
immunoglobulin quantification | Immunoglobulin concentrations (serum). | inbred (6) | both | 9-12wks | 2008 |
|
body weight | Body weight | inbred (14) | both | 9-12wks | 2003 |
|
body weight | Body weight | inbred (14) | both | 25wks | 2009 |
|
monitoring system | Locomotor activity. Aging study. 24h test with 12h light and 12h dark phases. | inbred (14) | both | 25wks | 2009 |
|
intake monitoring | Food intake, water intake at 6mo. Light phase, dark phase, total. | inbred (14) | both | 25wks | 2009 |
|
study archive | Colitis susceptibility, severity. Colon histopathology, body and spleen weight. | QTL population | both | 6wks | 2001 |
|
study archive | Blood pressure (tail cuff), kidney weight, body weight. | QTL population | m | 8wks | 2009 |
|
body weight
with influenza A (H1N1) virus |
Body weight | CC pre w/par (163) | f | 8-16wks | 2012 |
|
bottle choice test
with ethanol |
Voluntary consumption of ethanol, and ethanol with saccharin (several doses in water). | inbred (22) | both | 8-12wks | 2007 |
|
elevated zero maze | Anxiety-related behaviors. | inbred (8) | both | 8-9wks | 2001 |
|
electroconvulsion test
with lamotrigine |
Electroconvulsive thresholds. Lamotrigine. 2 test sites. | inbred (16) | both | 6-11wks | 2000 |
|
tail suspension test
with imipramine |
Immobility. Baseline (saline) vs. imipramine i.p. 6 min test. | inbred (12) | m | 5-10wks | 2003 |
|
light-dark box
with imipramine |
Anxiety-related behavior. Baseline (saline) vs. imipramine i.p. 10 min test. | inbred (12) | m | 5-10wks | 2003 |
|
open field test
with imipramine |
Locomotor activity, exploratory and anxiety-related behavior. Baseline (saline) vs. imipramine i.p. | inbred (12) | m | 5-10wks | 2003 |
|
open field test | Locomotor, exploratory, and anxiety-related behavior. 20 min test some at 5 min intervals. | inbred w/CC8 (8) | both | 8-9wks | 2020 |
|
grip strength | Several trials. | inbred w/CC8 (8) | both | 8-10wks | 2020 |
|
observation (SHIRPA) | Behavior, and neurosensory responses (SHIRPA protocol). | inbred w/CC8 (8) | both | 8-10wks | 2020 |
|
rotarod | Latency to fall from accelerating rotarod. | inbred w/CC7 (7) | both | 9-10wks | 2020 |
|
acoustic startle test | Acoustic startle response, prepulse inhibition. | inbred w/CC8 (8) | both | 9-10wks | 2020 |
|
metabolic panel | Glucose, glycerol. 16h fast. | inbred (5) | both | 10-11wks | 2020 |
|
lipid profile | Cholesterol, HDL, non-HDL, triglycerides, fatty acids. 16h fast, plasma. | inbred (5) | both | 10-11wks | 2020 |
|
monitoring system | Locomotor activity and energy metabolism. 21h test. | inbred w/CC8 (8) | both | 12-13wks | 2020 |
|
intake monitoring | Food, water intake. 21h test. | inbred w/CC8 (8) | both | 12-13wks | 2020 |
|
NMR | Body mass, fat and lean tissue mass. | inbred w/CC8 (8) | both | 12-13, 18-19wks | 2020 |
|
glucose tolerance | 0 to 120 min after 20% glucose i.p., 16h fast. | inbred w/CC8 (6) | both | 13-14wks | 2020 |
|
complete blood count | Hematology. | inbred w/CC8 (8) | both | 20-21wks | 2020 |
|
metabolic panel | Clinical blood chemistry (plasma). No fast. | inbred w/CC8 (8) | both | 16-17, 20-21wks | 2020 |
|
lipid profile | Cholesterol, triglycerides. No fast, plasma. | inbred w/CC8 (8) | both | 16-17, 20-21wks | 2020 |
|
body size and weight | Body weight and length. | inbred w/CC8 (8) | both | 17-18wks | 2020 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content, bone area. | inbred w/CC8 (8) | both | 17-18wks | 2020 |
|
immunoglobulin quantification | Immunoglobulins (plasma). | inbred w/CC8 (8) | both | 16-17, 20-21wks | 2020 |
|
autoantibody quantification | Anti-DNA autoantibodies, rheumatoid factor. | inbred w/CC8 (8) | both | 16-17, 20-21wks | 2020 |
|
open field test | Locomotor activity, exploratory and anxiety-related behavior. | inbred (8) | m | 10wks | 2003 |
|
forced swim test
with lithium |
Lithium (several doses) vs. control. 6 min test. | inbred (11) | m | 7-8wks | 2011 |
|
drug and metabolite quantification
with lithium |
Lithium concentration in brain tissue and blood serum after lithium (several doses). | inbred (11) | m | 7-8wks | 2011 |
|
drug and metabolite quantification
with nicotine |
Amount of nicotine and cotinine in blood plasma after nicotine doses. High and lower doses. | inbred (8) | m | 8-12wks | 2011 |
|
behavior observation
with nicotine |
Observed measures of anxiety. Nicotine (high dose) vs. control. 20 min period. | inbred (8) | m | 8-12wks | 2011 |
|
elevated plus maze
with nicotine |
Measures of anxiety. Nicotine (high dose) vs. control. 5 min test. | inbred (8) | m | 8-12wks | 2011 |
|
fear conditioning test
with nicotine |
Contextual fear, cued fear. Nicotine (high and several lower doses) vs. control. | inbred (8) | m | 8-12wks | 2011 |
|
behavior observation
with nicotine |
Observed measures of anxiety during nicotine withdrawal. Nicotine (several high doses) vs. control. | inbred (8) | m | 8-12wks | 2011 |
|
elevated plus maze
with nicotine |
Measures of anxiety during nicotine withdrawal. Nicotine (several high doses) vs. control. | inbred (8) | m | 8-12wks | 2011 |
|
fear conditioning test
with nicotine |
Contextual fear, cued fear during nicotine withdrawal. Nicotine (high and several lower doses) vs. control. | inbred (8) | m | 8-12wks | 2011 |
|
conditioned place preference test
with nicotine |
Nicotine preference and learning effect. Nicotine-treated vs. control. 2 trials (day 5, day 10). | inbred (8) | m | 8-10wks | 2014 |
|
body weight
with West Nile virus |
Body weight | CC RIX (5) | m | 8-10wks | 2015 |
|
RNA expression profiling
with West Nile virus |
Viral load and expression of Ifnb1 and Ifit1 in brain, kidney and spleen. | CC RIX (5) | m | 8-10wks | 2015 |
|
colony observation
with SARS-CoV |
Body weight loss and mortality. | CC RIX (117) | f | 8-10wks | 2021 |
|
immune cell quantification | Baseline splenic T cell subsets. | CC RIX (104) | m | 8-10wks | 2021 |
|
complete blood count
with ENU |
Hematology. | inbred (20) | both | 9wks; 12-64wks | 2006 |
|
histopathology
with ENU |
Tumor growth frequency rates. ENU mutagen 100 mg/kg vs. control. | inbred (20) | both | 9wks; 12-64wks | 2006 |
|
genotype assessment
with Candida albicans |
C5 allele sufficiency or deficiency. | inbred (36) | f | 8-12wks | 2011 |
|
study archive | Kidney morphology, renal cystic disease severity. | QTL population | f | 2wks | 2000 |
|
body weight | Body weight of newborns. | inbred (8) | both | postnatal | 2011 |
|
body weight | Body weight of newborns. | BXH (10) | both | postnatal | 2011 |
|
colony observation | Maternal nurturing study. | inbred (31) | f | 14-18wks | 2012 |
|
body weight | Daily body weight gain of cross-fostered pups. | inbred (31) | f | 14-18wks | 2012 |
|
mineral quantification | concentrations of various minerals in milk | inbred (31) | f | 14-20wks | 2018 |
|
study archive | eQTL, urinary albumin excretion using microarray. | QTL population | m | 8-10wks | 2011 |
|
body weight | Body weight | DO population | both | 8-60 wks | 2020 |
|
body weight | Body weight | inbred (14) | m | 8-10wks | 2010 |
|
body weight
with isoniazid |
Body weight. Isoniazid-treated vs. control. | inbred (34) | f | 8-10wks | 2011 |
|
organ weights
with isoniazid |
Body, liver, kidney weights. Isoniazid-treated vs. control. | inbred (34) | f | 8-10wks | 2011 |
|
metabolic panel
with isoniazid |
Alanine transaminase. Isoniazid-treated vs. control. | inbred (34) | f | 8-10wks | 2011 |
|
lipid profile
with isoniazid |
Cholesterol, triglycerides. Hepatic lipids. Isoniazid-treated vs. control. | inbred (34) | f | 8-10wks | 2011 |
|
histopathology
with isoniazid |
Liver pathology scores. Isoniazid-treated vs. control. | inbred (34) | f | 8-10wks | 2011 |
|
body weight
with DB289 |
DB289-treated vs. control. | inbred (34) | f | 6-8wks | 2012 |
|
metabolic panel
with DB289 |
Blood urea nitrogen, alanine transaminase, creatinine. DB289-treated vs. control. | inbred (34) | f | 6-8wks | 2012 |
|
urinalysis
with DB289 |
Urine volume, creatinine. DB289-treated vs. control. | inbred (34) | f | 6-8wks | 2012 |
|
biomarker quantification
with DB289 |
Kidney injury molecule 1 (KIM-1). DB289-treated vs. control. | inbred (34) | f | 6-8wks | 2012 |
|
organ weights
with DB289 |
Kidney and liver weights. DB289-treated vs. control. | inbred (34) | f | 6-8wks | 2012 |
|
drug and metabolite quantification
with DB289 |
Kidney metabolite (DB75) concentration. DB289-treated vs. control. | inbred (34) | f | 6-8wks | 2012 |
|
lipid profile | Cholesterol, HDL, non-HDL, triglycerides, free fatty acids. 16h fast, plasma. | HMDP (99) | m | 16wks | 2010 |
|
fear conditioning test | Contextual fear, cued fear. | HMDP (94) | m | 10wks | 2011 |
|
complete blood count | Hematology. | HMDP (83) | m | 16wks | 2013 |
|
study archive
with high-fat diet |
Lipids, atherosclerosis lesions, parathyroid hormone after high-fat diet. | QTL population | f | 20wks | 2004 |
|
colony observation
with (R/S)-1,3-butanediol, 17-a-estradiol, 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride, 2-(2-Hydroxyphenyl)benzoxazole, 3-(3-hydroxybenzyl)-5-methylbenzo[d]oxazol-2(3H)-one, 4-OH-a-phenyl-N-tert-butyl nitrone, 4-phenylbutyrate, acarbose, aspirin, astaxanthin, b-guanidinopropionic acid, caffeic acid phenethyl ester, canagliflozin, captopril, candesartan cilexetil, curcumin, dimethyl fumarate, enalapril, fisetin, fish oil, geranylgeranyl acetone, glycine, green tea extract, INT-767 FXR/TGR5 agonist, inulin, L-Leucine, meclizine, medium-chain triglyceride, metformin, metformin plus rapamycin, methylene blue, minocycline, MitoQ, mycophenolic acid, nicotinamide riboside, nitroflurbiprofen, nordihydroguaiaretic acid, oxaloacetic acid, PB125, protandim, rapamycin, rapamycin plus acarbose, resveratrol, SG1002, simvastatin, sulindac, syringaresinol, TM5441, ursodeoxycholic acid, ursolic acid, 16-a-hydroxyestriol, 2,4-dinitrophenol, a-Ketoglutarate, Hydralazine, Nebivolol, Sodium thiosulfate |
Life span study. Various interventions vs. controls. | UM-HET3 population | both | various | 2004-2024 |
|
body weight | Body weight and growth curve from age 3wks to 10 wks, weighed weekly. | inbred (24) | both | 8wks | 2000 |
|
open field test | Locomotor, exploratory, and anxiety-related behavior. 20 min test, some at 5 min intervals. | CC (18) | both | various | 2018 |
|
hole board test | Exploratory behavior. | CC (18) | both | various | 2018 |
|
acoustic startle test | Acoustic startle response, prepulse inhibition. | CC (18) | both | various | 2018 |
|
light-dark box | Anxiety, avoidance behavior. 20 min test. | CC (18) | both | various | 2018 |
|
tail suspension test | Latency to immobility, duration of immobility. | CC (18) | both | various | 2018 |
|
rotarod | Latency to fall from accelerating rotarod. 5 trials. | CC (18) | both | various | 2018 |
|
grip strength | 3 trials. | CC (18) | both | various | 2018 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content, bone area. | CC (18) | both | various | 2018 |
|
urinalysis | Microalbumin, creatinine, ratio. | CC (18) | both | various | 2018 |
|
metabolic panel | Clinical blood chemistry (plasma). No fast. | CC (18) | both | various | 2018 |
|
lipid profile | Cholesterol, HDL, triglycerides, fatty acids. No fast, plasma. | CC (18) | both | various | 2018 |
|
hormone quantification | Insulin (plasma). | CC (18) | both | various | 2018 |
|
complete blood count | Hematology. | CC (18) | both | various | 2018 |
|
grip strength | 3 trials. | KOMP | both | 8-18wks | 2021 |
|
open field test | Locomotor, exploratory, and anxiety-related behavior. 20 min test, some at 5 min intervals. | KOMP | both | 8-18wks | 2021 |
|
observation (SHIRPA) | Behavior, and neurosensory responses (SHIRPA protocol). | KOMP | both | 8-18wks | 2021 |
|
Y-maze | Spontaneous alternation and other parameters. 8 min test. | KOMP | both | 8-18wks | 2021 |
|
hole board test | Exploratory behavior. | KOMP | both | 8-18wks | 2021 |
|
light-dark box | Anxiety, avoidance behavior. 20 min test. | KOMP | both | 8-18wks | 2021 |
|
acoustic startle test | Acoustic startle response, prepulse inhibition. | KOMP | both | 8-18wks | 2021 |
|
rotarod | Latency to fall from accelerating rotarod. 5 trials. | KOMP | both | 8-18wks | 2021 |
|
tail suspension test | Latency to immobility, duration of immobility. | KOMP | both | 8-18wks | 2021 |
|
glucose tolerance | 0 to 120 min after 20% glucose i.p., 16h fast. | KOMP | both | 8-18wks | 2021 |
|
urinalysis | Microalbumin, creatinine, ratio. | KOMP | both | 8-18wks | 2021 |
|
lipid profile | Cholesterol, HDL, triglycerides, fatty acids. 4h fast, plasma. | KOMP | both | 8-18wks | 2021 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content, bone area. | KOMP | both | 8-18wks | 2021 |
|
monitoring system | Sleep parameters, light and dark periods. | KOMP | both | 8-18wks | 2021 |
|
metabolic panel | Clinical blood chemistry (plasma). No fast. | KOMP | both | 8-18wks | 2021 |
|
complete blood count | Hematology parameters. | KOMP | both | 8-18wks | 2021 |
|
hormone quantification | Insulin (plasma). | KOMP | both | 8-18wks | 2021 |
|
grip strength | 3 trials. | KOMP | both | 66-81wks | 2021 |
|
open field test | Locomotor, exploratory, and anxiety-related behavior. 20 min test, some at 5 min intervals. | KOMP | both | 66-81wks | 2021 |
|
observation (SHIRPA) | Behavior, and neurosensory responses (SHIRPA protocol). | KOMP | both | 66-81wks | 2021 |
|
Y-maze | Spontaneous alternation and other parameters. 8 min test. | KOMP | both | 66-81wks | 2021 |
|
hole board test | Exploratory behavior. | KOMP | both | 66-81wks | 2021 |
|
light-dark box | Anxiety, avoidance behavior. 20 min test. | KOMP | both | 66-81wks | 2021 |
|
acoustic startle test | Acoustic startle response, prepulse inhibition. | KOMP | both | 66-81wks | 2021 |
|
glucose tolerance | 0 to 120 min after 20% glucose i.p., 16h fast. | KOMP | both | 66-81wks | 2021 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content, bone area. | KOMP | both | 66-81wks | 2021 |
|
metabolic panel | Clinical blood chemistry (plasma). No fast. | KOMP | both | 66-81wks | 2021 |
|
complete blood count | Hematology parameters. | KOMP | both | 66-81wks | 2021 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content, bone area. | inbred (11) | both | 8, 16 wks | 2006 |
|
body weight | Body weight | inbred (11) | both | 8, 16 wks | 2006 |
|
body weight | Body weight | inbred (11) | both | 8, 16 wks | 2006 |
|
metabolic panel | Clinical blood chemistry (plasma). 4h fast. | inbred (11) | both | 8, 16 wks | 2006 |
|
lipid profile | Cholesterol, HDL, triglycerides, free fatty acids. 4h fast, plasma. | inbred (11) | both | 8, 16 wks | 2006 |
|
complete blood count | Hematology. | inbred (11) | both | 8, 16 wks | 2006 |
|
body weight | Body weight and growth curve from age 3wks to 16wks, weighed weekly. | inbred (10) | both | 3-16wks | 2014 |
|
body weight | Body weight | inbred (11) | both | 8, 16 wks | 2006 |
|
observation (SHIRPA) | Behavior, and neurosensory responses (SHIRPA protocol). | inbred (6) | m | 10wks | 2010 |
|
grip strength | Peak tension. | inbred (6) | m | 10wks | 2010 |
|
rotarod | Latency to fall from accelerating rotarod. | inbred (6) | m | 10wks | 2010 |
|
body weight | Body weight | inbred (7) | both | 8-14wks | 2003 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content (whole body, femur, spine). | inbred (7) | both | 8-14wks | 2003 |
|
operant conditioning chamber | Reversal learning test. Impulsivity, acquisition, reversal, conditioning. Performance and latency. | BXD w/par (53) | m | 17wks | 2011 |
|
operant conditioning chamber
with cocaine |
Intravenous self-administration of cocaine via activation of levers, and locomotor activity. | BXD (4) | both | 8-17wks | 2013 |
|
complete blood count | Hematology. | inbred (16) | both | 12-16wks | 2002 |
|
study archive | Characterization of high-muscle-mass mice. | QTL population | both | 3-10wks | 2011 |
|
balance beam | Latency to reach target. | inbred (6) | m | 20-34wks | 2009 |
|
grid test | Inverted grid performance. | inbred (6) | m | 20-34wks | 2009 |
|
home cage monitoring | Locomotor activity. | inbred (6) | m | 20-34wks | 2009 |
|
study archive | Glucose, insulin, body and fat pad weights. | QTL population | m | 20-26wks | 2001 |
|
histopathology
with cadmium |
Cadmium-induced toxicity to liver, testis, trigeminal ganglia. | inbred (8) | m | 8wks | 2001 |
|
monitoring system | Activity in a novel environment. Distance traveled, number of rears. 30 min test. | inbred (14) | both | 8wks | 2006 |
|
two chamber assay | Novel environment preference. Activity in familiar and novel compartments. 20 min test. | inbred (14) | both | 8wks | 2006 |
|
hole board test | Head dipping and other activity measures, hole board with and without objects in two of the holes. 10 min test. | inbred (14) | both | 8wks | 2006 |
|
Y-maze | Spontaneous alternation. | inbred (14) | both | 8wks | 2006 |
|
avoidance test | Active and passive. | wild-derived Mishima (11) | f | 8-13wks | 2000 |
|
home cage monitoring | Locomotor activity. | wild-derived Mishima (11) | f | 8-13wks | 2000 |
|
light-dark box | Anxiety-related behavior. | wild-derived Mishima (11) | f | 8-13wks | 2000 |
|
open field test | Exploratory, anxiety-related behavior. 10 min test. | wild-derived Mishima (12) | both | 10wks | 2006 |
|
urinalysis | Microalbumin, creatinine, ratio. Aging study, 6mo, 12mo, and 20mo. | inbred (30) | both | 52, 78, 104 wks | 2008 |
|
study archive
with cocaine |
Open field test. Locomotor, anxiety-related, circadian behavior. Baseline and after cocaine i.p. | QTL population | both | 10-14wks | 2014 |
|
open field test | Distance traveled, after first 10 min and after 55 min. | other (58) | both | 7-26wks | 2019 |
|
body weight | Body weight | inbred w/CC8 (62) | both | 8-14wks | 2021 |
|
open field test | Locomotor activity and grooming behavior. | inbred w/CC8 (62) | both | 8-14wks | 2021 |
|
body size and weight | Body length measurements. | inbred w/CC8 (62) | both | 10-20 wks | 2021 |
|
open field test | Distance traveled. | inbred w/CC8 (62) | both | 10-20 wks | 2021 |
|
gait analysis | Angular velocity, Stride speed, Step length, Step width, and other gait metrics. | inbred w/CC8 (62) | both | 10-20 wks | 2021 |
|
complete blood count | Hematology. | B6.A consomic w/par (23) | both | 7-11wks | 2005 |
|
metabolic panel | Glucose, bilirubin, aspartate transaminase (plasma). 4h fast. | B6.A consomic w/par (23) | both | 7-11wks | 2005 |
|
lipid profile | Cholesterol, HDL, triglycerides, fatty acids. 4h fast, plasma. | B6.A consomic w/par (23) | both | 7-11wks | 2005 |
|
observation (SHIRPA) | Behavior, and neurosensory responses (SHIRPA protocol). | B6.A consomic w/par (23) | both | 8wks | 2005 |
|
rotarod | Latency to fall from fixed and accelerating rotorods, multiple trials. | B6.A consomic w/par (23) | both | 8-9wks | 2005 |
|
hole board test | Exploratory, locomotor, and anxiety-related behavior. | B6.A consomic w/par (23) | both | 8-9wks | 2005 |
|
grip strength | 3 trials. | B6.A consomic w/par (23) | both | 8-9wks | 2005 |
|
study archive | Type 1 diabetes development study. | QTL population | f | 14-40wks | 2009 |
|
body weight | Body weight | CC pre (31) | both | 8-14wks | 2015 |
|
study archive
with western diet |
Lipids, atherosclerosis lesion histopathology. High-fat, western-style diet. | QTL population | f | 12wks | 2008 |
|
body weight | Body weight | inbred (41) | both | 8-9wks | 2010 |
|
running wheel monitoring | Distance, duration, speed. | inbred (41) | both | 8-9wks | 2010 |
|
body weight
with exercise |
Exercise (swim endurance training regimen) vs. control at weekly intervals for 5wks. | inbred (6) | m | 11-14wks | 2012 |
|
microscopy
with exercise |
Muscle fibers. Exercised (swim endurance training regimen) vs. control at weekly intervals for 5wks. | inbred (6) | m | 11-14wks | 2012 |
|
muscle weights
with exercise |
Various muscles. Exercised (swim endurance training regimen) vs. control at weekly intervals for 5wks. | inbred (6) | m | 11-14wks | 2012 |
|
organ weights
with exercise |
Heart weight. Cardiac ventricle weight. Exercised (swim endurance training regimen) vs. control at weekly intervals for 5wks. | inbred (6) | m | 11-14wks | 2012 |
|
bone dimensions
with exercise |
Femur length. Exercised (swim endurance training regimen) vs. control at weekly intervals for 5wks. | inbred (6) | m | 11-14wks | 2012 |
|
swim endurance test
with exercise |
Exercise vs. control, weekly for 5wks. | inbred (6) | m | 11-14wks | 2012 |
|
protein activity assessment
with exercise |
Muscle enzyme levels. Exercised (swim endurance training regimen) vs. control at weekly intervals for 5wks. | inbred (6) | m | 11-14wks | 2012 |
|
home cage monitoring | Locomotor activity, avoidance, sheltering, habituation, preference index, aversion index, over several days. | inbred (8) | m | 8-19wks | 2012 |
|
home cage monitoring | Locomotor activity, sheltering, habituation. 3 day home-cage assessment. | inbred w/CC7 (11) | m | 8-12wks | 2016 |
|
study archive
with high-fat diet |
Lipids (plasma), liver weight, gallbladder and gallstone histopathology. | QTL population | m | 16-18wks | 2003 |
|
study archive
with high-fat diet |
Lipids (plasma), bile, liver weight, gallbladder and gallstone histopathology. | QTL population | m | 16-18wks | 2003 |
|
study archive
with high-fat diet |
Lipids, gallbladder and gallstone histopathology after high-fat diet. | QTL population | m | 14-20wks | 2004 |
|
body weight | Body weight | CC (16) | both | 10wks | 2015 |
|
rotarod | Speed where mouse falls off accelerating rotarod, 45 degree angle, 3-5 trials. | CC (16) | both | 10wks | 2015 |
|
body weight | Body weight | inbred (34) | both | 8wks | 2012 |
|
treadmill endurance test | Duration, distance, work. | inbred (34) | both | 8wks | 2012 |
|
body weight
with exercise |
Baseline vs. after exercise (access to running wheel). | CC pre w/par (184) | m | 10-12wks | 2011 |
|
MRI
with exercise |
Body composition (percent fat). Baseline vs. after exercise (access to running wheel). | CC pre w/par (184) | m | 10-12wks | 2011 |
|
intake monitoring
with exercise |
Caloric intake. Baseline vs. after exercise (access to running wheel). Metabolism, food intake. | CC pre w/par (184) | m | 10-12wks | 2011 |
|
monitoring system
with exercise |
Respiratory exchange ratio. Baseline (before access to running wheel). | CC pre w/par (184) | m | 10-12wks | 2011 |
|
running wheel monitoring
with exercise |
Distance, speed at days 1, 6, and 12. | CC pre w/par (184) | m | 10-12wks | 2011 |
|
study archive | Type 1 diabetes resistance. | QTL population | f | 8-40wks | 2003 |
|
body weight
with atenolol, isoproterenol |
Isoproterenol or atenolol vs. control. | inbred (23) | m | 10-12wks | 2009 |
|
organ weights
with atenolol, isoproterenol |
Heart, atria, ventricle weights. Isoproterenol or atenolol vs. control. | inbred (23) | m | 10-12wks | 2009 |
|
tail cuff
with atenolol, isoproterenol |
Heart rate and blood pressure. Conscious mice. Isoproterenol or atenolol vs. control. | inbred (23) | m | 10-12wks | 2009 |
|
ECG
with atenolol, isoproterenol |
Heart rate and wave amplitudes and intervals. Unconscious. Isoproterenol or atenolol vs. control. | inbred (23) | m | 10-12wks | 2009 |
|
MRI | Body composition (fat and lean mass and percent). | CC (50) | f | 17-72wks | 2017 |
|
treadmill endurance test | Maximal distance is recorded when mouse fails to run. | CC (50) | f | 17-72wks | 2017 |
|
running wheel monitoring | Running wheel activity each day for 28 days. | CC (43) | f | 5-22wks | 2017 |
|
body weight | Body weight before, during, and after several weeks of exercise. | CC (43) | f | 20-88wks | 2017 |
|
MRI | Body composition (fat and lean mass) before, during, and after several weeks of exercise. | CC (43) | f | 20-88wks | 2017 |
|
intake monitoring | Food intake, before, during, and after several weeks of exercise. | CC (43) | f | 20-88wks | 2017 |
|
body weight
with exercise |
Body weight before and after 2 weeks of exercise wheel availability. | CC (13) | f | 32-40wks | 2018 |
|
MRI
with exercise |
Body composition (fat and lean mass) before and after 2 weeks of exercise wheel availability. | CC (13) | f | 32-40wks | 2018 |
|
running wheel monitoring
with exercise |
Running wheel activity on days 11 and 12. | CC (13) | f | 32-40wks | 2018 |
|
intake monitoring
with exercise |
Food intake during 2 weeks of exercise wheel availability. | CC (13) | f | 32-40wks | 2018 |
|
body weight
with exercise |
Body weight before and after 4 weeks of treadmill-based exercise training. 3 intensity cohorts. | CC (4) | both | 8-10wks | 2018 |
|
MRI
with exercise |
Body composition (fat and lean mass) before and after 4 weeks of treadmill-based exercise training. 3 intensity cohorts. | CC (4) | both | 8-10wks | 2018 |
|
monitoring system
with exercise |
Locomotor activity, respiratory activity, body heat production, during 4 weeks of treadmill-based exercise training. 3 intensity cohorts. | CC (4) | both | 8-10wks | 2018 |
|
intake monitoring
with exercise |
Food and water intake, during 4 weeks of treadmill-based exercise training. 3 intensity cohorts. | CC (4) | both | 8-10wks | 2018 |
|
behavior observation
with ethanol |
Observed gait, hindlimb splay 10 min and 30 min after ethanol i.p. (several doses). | inbred (9) | both | 8-11wks | 2004 |
|
open field test
with ethanol |
Locomotor activity. Ethanol i.p. (several doses) vs. control (saline i.p.). 45s test. | inbred (9) | both | 8-11wks | 2004 |
|
body weight
with ethanol |
Body weight | inbred (15) | m | 8-11wks | 2005 |
|
behavior observation
with ethanol |
Ethanol withdrawal severity and handling-induced convulsions. | inbred (15) | m | 8-11wks | 2005 |
|
go/no-go task | Pre-cue, go cue. no-go cue. Discrimination index. | inbred (15) | m | 5-7wks | 2010 |
|
monitoring system | Locomotor activity. | inbred (15) | m | 5-7wks | 2010 |
|
monitoring system | Locomotor activity. Light and dark phases. | inbred (12) | m | 6-10wks | 2000 |
|
monitoring system | Social interaction and discrimination; activity, digging, grooming. | CC (52) | m | 7-20wks | 2018 |
|
body weight | Body weight | CC (52) | m | 7-20wks | 2018 |
|
protein activity assessment | Acetylcholinesterase activity of cerebellum and dorsal and ventral hippocampus | inbred (20) | m | 8-12wks | 2021 |
|
body weight
with high-fat diet and olanzapine |
Body weight and growth curve from age 8wks to 18wks weighed every 2wks. Olanzapine vs. control (both groups high-fat diet). | inbred w/CC8 (9) | f | 8-18wks | 2014 |
|
three chamber assay | Sociability and preference for social novelty. Autism-relevant behaviors. | inbred (17) | m | 6-7wks | 2008 |
|
study archive | Kidney morphology. | QTL population | both | 1-2wks | 2005 |
|
body weight
with high-fat diet |
Baseline vs. high-fat diet for 12wks. | B6.A consomic w/par (24) | m | 5, 17 wks | 2008 |
|
body size and weight
with high-fat high-sucrose diet |
Body weight, size, and body mass index after 16wks on high-fat high-sucrose diet. | B6.A consomic w/par (24) | m | 5, 21 wks | 2015 |
|
metabolic panel
with high-fat high-sucrose diet |
Glucose, insulin, insulin resistance after 16wks of high-fat high-sucrose diet. 16h fast. | B6.A consomic w/par (24) | m | 5, 21 wks | 2015 |
|
lipid profile
with high-fat high-sucrose diet |
Cholesterol, triglycerides. 16h fast, plasma. Hepatic triglycerides. | B6.A consomic w/par (24) | m | 5, 21 wks | 2015 |
|
body weight
with high-fat high-sucrose diet |
After 16 wks on high-fat high-sucrose diet. | inbred (2) | m | 21 wks | 2016 |
|
body size and weight
with high-fat high-sucrose diet |
Body weight and body mass index after 16 wks of high-fat high-sucrose diet. | inbred (2) | m | 21 wks | 2016 |
|
hormone quantification
with high-fat high-sucrose diet |
Insulin and insulin resistance after 16 wks of high-fat high-sucrose diet. Overnight fast. | inbred (2) | m | 21 wks | 2016 |
|
lipid profile
with high-fat high-sucrose diet |
Cholesterol and triglycerides. Overnight fast, plasma. Hepatic triglycerides. | inbred (2) | m | 21 wks | 2016 |
|
body weight
with high-fat high-sucrose diet |
High-fat high-sucrose diet for 14-15 wks | B6.A consomic w/par (3) | m | 4-19 wks | 2016 |
|
body size and weight
with high-fat high-sucrose diet |
Body length and body mass index after high-fat high-sucrose diet for 14-15 wks | B6.A consomic w/par (3) | m | 4-19 wks | 2016 |
|
body weight
with high-fat diet |
High-fat diet for 8wks. | inbred w/CC7 (43) | both | 5, 21 wks | 2003 |
|
DXA
with high-fat diet |
Body mass, fat mass, lean mass, bone mineral density and content after 8wks on high-fat diet. | inbred w/CC7 (43) | both | 5, 21 wks | 2003 |
|
metabolic panel
with high-fat diet |
Glucose (plasma). Baseline vs. high-fat diet (17wks). 4h fast. | inbred w/CC7 (43) | both | 5, 21 wks | 2003 |
|
hormone quantification
with high-fat diet |
Insulin and leptin after 18wks on high-fat diet. Multiple readings per animal were averaged. | inbred w/CC7 (43) | both | 5, 21 wks | 2003 |
|
body weight
with restricted diet |
Restricted diet vs. ad libitum diet. | ILSXISS (44) | both | max lifespan | 2010 |
|
NMR
with restricted diet |
Body mass, fat mass, lean mass. Restricted diet vs. ad libitum diet. | ILSXISS (44) | both | max lifespan | 2010 |
|
colony observation
with restricted diet |
Life span comparison. Restricted diet vs. ad libitum diet. | ILSXISS (44) | both | max lifespan | 2010 |
|
body weight | Measured every 2 mo, starting at age 2 mo to 16 mo. | F1 AD-BXD (55) | both | 7-65wks | 2019 |
|
Y-maze | Spontaneous alternation and other parameters measured every 2 mo, from age 2 to 16 mo. | F1 AD-BXD (55) | both | 7-65wks | 2019 |
|
balance beam | Time to cross narrow beam, age 6 and 14 mo. | F1 AD-BXD (55) | both | 7-65wks | 2019 |
|
inclined screen test | Time to right body, age 6 and 14 mo. | F1 AD-BXD (55) | both | 7-65wks | 2019 |
|
grip strength | Grip strength across 3 trials, age 6 mo and 14 mo. | F1 AD-BXD (55) | both | 7-65wks | 2019 |
|
behavior observation | Sensorimotor composite score, age 6 mo and 14 mo. | F1 AD-BXD (55) | both | 7-65wks | 2019 |
|
elevated plus maze | Distance traveled and arm entries, age 6 mo and 14 mo. | F1 AD-BXD (55) | both | 7-65wks | 2019 |
|
fear conditioning test | Time spent freezing, age 6 mo and 14 mo. | F1 AD-BXD (55) | both | 7-65wks | 2019 |
|
immunoglobulin quantification | IgM, IgG1, IgG2a + IgG2c, IgG2b, IgG3, total IgG | CC RIX (46) | f | 8-12 wks of age | 2020 |
|
body weight | Body weight | inbred (8) | m | 10-66wks | 2015 |
|
metabolic panel | Male reproductive sperm lactate production. | inbred (8) | m | 10-66wks | 2015 |
|
body weight
with high-fat diet |
Baseline vs. high-fat diet for 8wks. | inbred (44) | both | 15-19wks | 2000 |
|
lipid profile
with high-fat diet |
Cholesterol, HDL, non-HDL. 4h fast, plasma. Hepatic lipids. 8wks on high-fat diet. | inbred (44) | both | 15-19wks | 2000 |
|
metabolic panel
with high-fat diet |
Alanine transaminase, bile salts (plasma) after 8wks on high-fat diet. 4h fast. | inbred (44) | both | 15-19wks | 2000 |
|
lipid profile
with high-fat diet |
Cholesterol, HDL, non-HDL, triglycerides. Baseline vs. high-fat diet (17wks). 4h fast, plasma. | inbred w/CC7 (43) | both | 7-9wks, 24-27wks | 2002 |
|
body weight
with high-fat diet |
Baseline vs. high-fat diet for 8wks. | obesity mutants (8) | both | 15-19wks | 2000 |
|
lipid profile
with high-fat diet |
Cholesterol, HDL, non-HDL. 4h fast, plasma. Hepatic lipids. 8wks on high-fat diet. | obesity mutants (8) | both | 15-19wks | 2000 |
|
metabolic panel
with high-fat diet |
Alanine transaminase, bile salts (plasma) after 8wks on high-fat diet. 4h fast. | obesity mutants (8) | both | 15-19wks | 2000 |
|
lipid profile | Cholesterol, HDL, non-HDL, triglycerides. 4h fast, plasma. | inbred w/CC7 (43) | both | 10wks | 2002 |
|
fear conditioning test | Innate anxiety-like behavior and contextual fear conditioning. | B6.A consomic w/par (19) | both | 10wks | 2007 |
|
open field test
with methamphetamine |
Locomotor activity and habituation. Baseline (saline) vs. methamphetamine 2 mg/kg i.p. 30 min test. | B6.A consomic w/par (21) | both | 10wks | 2008 |
|
body weight | Body weight | F1 Tcf7l2 (30) | both | 7-14wks | 2017 |
|
open field test | Locomotor and exploratory behavior. 30 min test. | F1 Tcf7l2 (30) | both | 7-14wks | 2017 |
|
fear conditioning test | Contextual fear, cued fear. | F1 Tcf7l2 (30) | both | 7-14wks | 2017 |
|
acoustic startle test | Acoustic startle response, prepulse inhibition. | F1 Tcf7l2 (30) | both | 7-14wks | 2017 |
|
forced swim test | Immobility time. 6 min test. | F1 Tcf7l2 (30) | both | 7-14wks | 2017 |
|
metabolic panel | Glucose (blood). Before and after 16h fast. | F1 Tcf7l2 (30) | both | 7-14wks | 2017 |
|
body weight
with methamphetamine |
Body weight | F1 Cacna1c (30) | both | 7-14wks | 2017 |
|
light-dark box
with methamphetamine |
Anxiety-related. 5 min test. | F1 Cacna1c (30) | both | 7-14wks | 2017 |
|
open field test
with methamphetamine |
Locomotor and exploratory activity, anxiety-related behavior, methamphetamine sensitivity. 30 min test. | F1 Cacna1c (30) | both | 7-14wks | 2017 |
|
forced swim test
with methamphetamine |
Immobility time. 6 min test. | F1 Cacna1c (30) | both | 7-14wks | 2017 |
|
acoustic startle test
with methamphetamine |
Acoustic startle response. | F1 Cacna1c (30) | both | 7-14wks | 2017 |
|
body weight | Body weight | F1 Tcf7l2 (30) | both | 7-14wks | 2017 |
|
open field test | Locomotor and exploratory behavior. 30 min test. | F1 Tcf7l2 (30) | both | 7-14wks | 2017 |
|
fear conditioning test | Contextual fear, cued fear. | F1 Tcf7l2 (30) | both | 7-14wks | 2017 |
|
acoustic startle test | Acoustic startle response, prepulse inhibition. | F1 Tcf7l2 (30) | both | 7-14wks | 2017 |
|
forced swim test | Immobility time. 6 min test. | F1 Tcf7l2 (30) | both | 7-14wks | 2017 |
|
metabolic panel | Glucose (blood). Before and after 16h fast. | F1 Tcf7l2 (30) | both | 7-14wks | 2017 |
|
body weight
with methamphetamine |
Body weight | F1 Cacna1c (30) | both | 7-14wks | 2017 |
|
light-dark box
with methamphetamine |
Anxiety-related. 5 min test. | F1 Cacna1c (30) | both | 7-14wks | 2017 |
|
open field test
with methamphetamine |
Locomotor and exploratory activity, anxiety-related behavior, methamphetamine sensitivity. 30 min test. | F1 Cacna1c (30) | both | 7-14wks | 2017 |
|
forced swim test
with methamphetamine |
Immobility time. 6 min test. | F1 Cacna1c (30) | both | 7-14wks | 2017 |
|
acoustic startle test
with methamphetamine |
Acoustic startle response. | F1 Cacna1c (30) | both | 7-14wks | 2017 |
|
study archive | Body weight of Gough Island mice. | QTL population | both | 1-16wks | 2015 |
|
complete blood count | Hematology. | inbred w/CC7 (43) | both | 10wks | 2001 |
|
complete blood count | Hematology. | AXB BXA (28) | both | 11wks | 2004 |
|
complete blood count | Hematology. Aging study, 6mo, 12mo, 18mo, 24mo. | inbred (30) | both | 26, 52, 78, 104 wks | 2007 |
|
study archive | Complete blood count measures on fetuses, newborns. | QTL population | both | fetus, newborn | 2004 |
|
acoustic startle test | Acoustic startle response, prepulse inhibition. | B6.A consomic (22) | m | 7-9wks | 2009 |
|
study archive
with high-fat diet |
Cholesterol (plasma) after high-fat diet (several timepoints). | QTL population | f | 6-26wks | 2002 |
|
body weight | Body weight | inbred (32) | m | 7-9wks | 2007 |
|
open field test | Locomotor and anxiety-related behavior. 10 min test. | inbred (32) | m | 7-9wks | 2007 |
|
tail suspension test | Immobility percentage. | inbred (32) | m | 7-9wks | 2007 |
|
hormone quantification | Corticosterone (serum). | inbred (32) | m | 7-9wks | 2007 |
|
body size and weight | Body weight, body length, body mass index. | inbred (28) | m | 8, 12 wks | 2009 |
|
body size and weight | Body weight, body length, body mass index. | B6.129 and 129.B6 consomic w/par (9) | both | 26wks | 2015 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content, bone area. High-fat diet vs. control. Two age cohorts. | B6.129 and 129.B6 consomic w/par (9) | both | 26wks | 2015 |
|
study archive | Body weight (several ages), fat mass, body mass index, fat pad weights. | QTL population | m | 4-24wks | 2000 |
|
study archive | Type 1 diabetes onset. | QTL population | f | 12-40wks | 2005 |
|
running wheel monitoring
with exercise |
Locomotor activity. Exercise wheel group vs. control group. Distance per day. | inbred (12) | both | 8-15wks | 2010 |
|
body weight
with exercise |
Exercise wheel group vs. control group. | inbred (12) | both | 8-15wks | 2010 |
|
microscopy
with exercise |
Examination of hippocampus dentate gyrus. Exercise wheel group vs. control group. | inbred (12) | both | 8-15wks | 2010 |
|
proteomic profiling | Hair proteomics analysis. Spectral counts for 46 specific proteins. | inbred (11) | both | 10-19wks | 2012 |
|
study archive
with macronutrient diet option |
Caloric intake, glucose, body and fat pad weights. Macronutrient diet option. | QTL population | m | 8-13wks | 2002 |
|
open field test | Locomotor activity. 3 day trials. 45 min sessions. | inbred (15) | m | 7-9wks | 2003 |
|
neurotransmitter quantification | Neurotransmitters. Molecular measures. | inbred (15) | m | 7-9wks | 2003 |
|
metabolic panel | Clinical blood chemistry (plasma). 4h fast. | inbred RBRC (56) | both | 8, 12 wks | 2008 |
|
complete blood count | Hematology. | inbred RBRC (56) | both | 8, 12 wks | 2008 |
|
lipid profile | Cholesterol, HDL, triglycerides. 4h fast, plasma. | inbred RBRC (56) | both | 8, 12 wks | 2008 |
|
body size and weight | Body weight, body length, tail length. | inbred RBRC (56) | both | 8, 12 wks | 2008 |
|
metabolic panel | Clinical blood chemistry (plasma). 4h fast. | wild-derived RBRC (33) | both | 8, 12 wks | 2008 |
|
complete blood count | Hematology. | wild-derived RBRC (33) | both | 8, 12 wks | 2008 |
|
lipid profile | Cholesterol, HDL, triglycerides. 4h fast, plasma. | wild-derived RBRC (33) | both | 8, 12 wks | 2008 |
|
body size and weight | Body weight, body length, tail length. | wild-derived RBRC (33) | both | 8, 12 wks | 2008 |
|
metabolic panel
with trichloroethylene |
Blood urea nitrogen, alanine transaminase, aspartate transaminase (serum). Baseline and trichloroethylene-exposed (several timepoints). No fast. | inbred (17) | m | 7wks | 2010 |
|
drug and metabolite quantification
with trichloroethylene |
Trichloroethylene metabolites in serum, 2h, 4h, 24h after trichoroethylene exposure. | inbred (17) | m | 7wks | 2010 |
|
metabolic panel
with high-fat diet and ethanol |
Alanine transaminase (serum) after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. | inbred (14) | m | 8-14wks | 2011 |
|
alcohol quantification
with high-fat diet and ethanol |
Alcohol concentration in blood and urine after 4 wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. | inbred (14) | m | 8-14wks | 2011 |
|
organ weights
with high-fat diet and ethanol |
Liver weight after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. | inbred (14) | m | 8-14wks | 2011 |
|
histopathology
with high-fat diet and ethanol |
Liver histopathology, injury after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. | inbred (14) | m | 8-14wks | 2011 |
|
metabolite quantification
with high-fat diet and ethanol |
Homocysteine concentration after 4wk regimen of ethanol vs. control, both groups on high-fat diet. 24h fast. | inbred (14) | m | 8-14wks | 2011 |
|
lipid profile
with high-fat diet and ethanol |
Hepatic triglycerides after 4wk regimen of ethanol and high-fat diet. 24h fast. | inbred (14) | m | 8-14wks | 2011 |
|
RNA expression profiling
with high-fat diet and ethanol |
Liver gene expression after 4wk regimen of ethanol and high-fat diet. 24h fast. mRNA abundance relative to the control (high-fat only) group. | inbred (14) | m | 8-14wks | 2011 |
|
organ weights
with trichloroethylene |
Liver, kidney weights. Trichloroethylene-exposed vs. control. | inbred (7) | m | 6-7wks | 2014 |
|
metabolic panel
with trichloroethylene |
Blood urea nitrogen (serum). Trichloroethylene-exposed vs. control. | inbred (7) | m | 6-7wks | 2014 |
|
drug and metabolite quantification
with trichloroethylene |
Trichloroethylene metabolite in blood, liver, kidney after trichloroethylene exposure. | inbred (7) | m | 6-7wks | 2014 |
|
RNA expression profiling
with trichloroethylene |
Trichloroethylene effect on mRNA gene expression in liver and kidney, relative to controls. | inbred (7) | m | 6-7wks | 2014 |
|
histopathology
with trichloroethylene |
Kidney histopathology evaluation after trichloroethylene exposure, relative to controls. | inbred (7) | m | 6-7wks | 2014 |
|
health assessment | Post-injury wound healing. Ear cartilage and articular cartilage. | LGXSM w/par (15) | both | 6-7wks | 2012 |
|
histopathology | Post-injury wound healing. Articular cartilage at 12wks and 16wks post-injury. | LGXSM w/par (15) | both | 6-7wks | 2012 |
|
Morris water maze | Spatial learning and memory. Multiple trials. | inbred (8) | m | 9-11wks | 2010 |
|
light-dark box | Anxiety-related behavior. | inbred (8) | m | 9-11wks | 2010 |
|
open field test | Locomotor activity and exploratory behavior. 5 min test. | inbred (8) | m | 9-11wks | 2010 |
|
elevated plus maze | Anxiety-related and exploratory behavior. 5 min test. | inbred (8) | m | 9-11wks | 2010 |
|
puzzle box | Learning and memory. | inbred (8) | m | 9-11wks | 2010 |
|
tail suspension test | Duration of immobility. Two trials. | inbred (8) | m | 9-11wks | 2010 |
|
health assessment
with pilocarpine |
Study of pilocarpine effect on epilepticus seizures. | inbred (11) | m | 8-10wks | 2012 |
|
body weight
with various diets |
Body weight at weaning and time of test. Comparison of 4 diets. | CC RIX (18) | f | 8-9 wks | 2018 |
|
open field test
with various diets |
Locomotor activity, anxiety-related behavior. 10 min test. Comparison of 4 diets. | CC RIX (18) | f | 8-9 wks | 2018 |
|
light-dark box
with various diets |
Anxiety-related behavior. 10 min test. Comparison of 4 diets. | CC RIX (18) | f | 8-9 wks | 2018 |
|
body temperature
with various diets |
Temperature before and after stress. Comparison of 4 diets. | CC RIX (18) | f | 8-9 wks | 2018 |
|
forced swim test
with various diets |
Immobility time. 6 min test. Comparison of 4 diets. | CC RIX (18) | f | 8-9 wks | 2018 |
|
hormone quantification
with various diets |
Serum corticosterone at baseline and 10 mins after stress. Comparison of 4 diets. | CC RIX (18) | f | 8-9 wks | 2018 |
|
body weight | Body weight | inbred (11) | both | 8-10wks | 2005 |
|
glucose tolerance | 0 to 120 min after 10% glucose i.p. 5h fast. | inbred (11) | both | 8-10wks | 2005 |
|
insulin tolerance | 0 to 120 min after insulin i.p. 5h fast. | inbred (11) | both | 8-10wks | 2005 |
|
lipid profile | Cholesterol, triglycerides, free fatty acids, phospholipids. 5h fast, plasma. Hepatic triglycerides. | inbred (11) | both | 8-10wks | 2005 |
|
metabolic panel | Glucose, beta-hydroxybutyrate (plasma). No fast. | inbred (11) | both | 8-10wks | 2005 |
|
DXA | Fat mass. | inbred (11) | both | 8-10wks | 2005 |
|
hormone quantification | Insulin level, 30 min post-injection in glucose tolerance test. 10% glucose. 5h fast. | inbred (11) | both | 8-10wks | 2005 |
|
body weight
with high-fat diet |
At 8, 20 and 29 wks of age. | BXD w/par (36) | m | 8-29 wks | 2022 |
|
glucose tolerance
with high-fat diet |
Plasma glucose levels at 0, 30, 60 min post oral gavage of Ensure Plus, overday fast. | BXD w/par (36) | m | 8-29 wks | 2022 |
|
biomarker quantification
with high-fat diet |
Bile acid levels in plasma, feces, and liver. | BXD w/par (36) | m | 8-29 wks | 2022 |
|
body weight
with influenza A (H1N1) virus |
Influenza A (H1N1) virus vs. baseline. Several timepoints. | inbred (9) | both | 10-12wks | 2009 |
|
body weight
with influenza A (H1N1) virus |
Influenza A (H1N1) virus vs. baseline. Several timepoints.. | BXD w/par (56) | f | 9-18wks | 2012 |
|
body weight
with influenza A (H3N2) virus |
Influenza A (H3N2) virus (several doses) vs. baseline. Several timepoints. | inbred w/CC8 (8) | both | 7-13wks | 2013 |
|
body weight
with influenza A (H3N2) virus |
Influenza A (H3N2) virus vs. controls. Several timepoints. | inbred w/CC8 (8) | f | 8-12wks | 2016 |
|
body weight
with influenza A (H3N2) virus |
Influenza A (H3N2) virus vs. controls. Several timepoints. | inbred w/CC8 (8) | f | 8-12wks | 2016 |
|
body weight | Body weight | inbred (7) | both | 9-18wks | 2000 |
|
bronchoalveolar lavage assessment
with ovalbumin |
Lung inflammatory changes. Ovalbumin vs. control. | inbred (8) | m | 6-8wks | 2001 |
|
body weight | Body weight | inbred (16) | both | 7-9wks | 2001 |
|
monitoring system | Locomotor activity and energy metabolism. 24h test. | inbred (16) | both | 7-9wks | 2001 |
|
intake monitoring | Food, caloric, and water intake. Daily. | inbred (16) | both | 7-9wks | 2001 |
|
grip strength | Peak tension. 3 trials. Aging study, 6mo, 12mo, 18mo, 24mo. | inbred (32) | both | 26, 52, 78, 104 wks | 2008 |
|
gait analysis | Aging study, 6mo, 18mo. | inbred (32) | both | 26, 52, 78, 104 wks | 2008 |
|
study archive | Urinalysis. Creatinine, microalbumin, body weight. | QTL population | m | 10wks | 2007 |
|
study archive | Circadian activity. | QTL population | both | 2001 | |
|
observational fear learning test | Percent time freezing to conditioning and contextual exposure. | inbred (11) | m | 12-14wks | 2016 |
|
fear conditioning test | Pavlovian fear conditioning. | inbred (11) | m | 12-14wks | 2016 |
|
open field test | Locomotor activity and exploratory behavior. 5 min test. | inbred (11) | m | 12-14wks | 2016 |
|
elevated plus maze | Exploratory and anxiety-related behaviors. 5 min test. | inbred (11) | m | 12-14wks | 2016 |
|
three chamber assay | Sociability testing. Tolerance of a novel mouse, a novel object, and second novel mouse vs. first. 10 min test. | inbred (11) | m | 12-14wks | 2016 |
|
body weight
with high-fat diet |
High-fat diet for 4wks vs. control. | inbred (10) | both | 10-13wks | 2008 |
|
lipid profile
with high-fat diet |
Cholesterol, HDL, triglycerides, fatty acids. High-fat diet (4wks) vs. control. 5h fast, serum. | inbred (10) | both | 10-13wks | 2008 |
|
metabolic panel
with high-fat diet |
Clinical blood chemistry measures (serum). High-fat diet (4wks) vs. control. | inbred (10) | both | 10-13wks | 2008 |
|
body weight | Body weight | CC (12) | m | 15-33wks | 2020 |
|
body weight | Body weight | CC RIX (28) | m | 7-44wks | 2020 |
|
body weight | Body weight | DO population | m | 12-15wks | 2020 |
|
study archive | Open field test, forced swim test, defensive burying task. | QTL population | both | 11-17wks | 2004 |
|
acoustic startle test | Acoustic startle response, prepulse inhibition. | BXD w/par (45) | m | 8wks | 2011 |
|
choice serial reaction time task | Choice serial reaction time task. Impulsivity, attention, cognitive flexibility behavior. | BXD w/par (45) | m | 8wks | 2011 |
|
home cage monitoring | Exploratory behavior. 4 min and 10 min tests. | inbred (12) | m | 6wks | 2009 |
|
open field test | Locomotor activity and exploratory behavior. 10 min test. | inbred (12) | m | 6wks | 2009 |
|
light-dark box | Anxiety, avoidance behavior. 5 min test. | inbred (12) | m | 6wks | 2009 |
|
elevated plus maze | Exploratory and anxiety-related behaviors. 5 min test. | inbred (12) | m | 6wks | 2009 |
|
choice serial reaction time task | Choice serial reaction time task. Impulsivity, attention, cognitive flexibility behavior. 25 min test. | inbred (12) | m | 6wks | 2009 |
|
study archive
with high-fat diet |
Body size, weight, fat pad weights after high-fat diet. | QTL population | both | 24wks | 2006 |
|
study archive | Lipids. Cholesterol, triglycerides, body weight. | QTL population | both | 8-10wks | 2006 |
|
study archive
with high-fat diet |
Lipids (plasma). Cholesterol, triglycerides, aortic lesions, body mass index. | QTL population | f | 14wks | 2009 |
|
study archive | Blood pressure (tail cuff), heart weight, body weight. | QTL population | m | 10wks | 2002 |
|
body weight
with selenium |
Body weight curve 3 to 12 wks, control group. | inbred w/CC8 (8) | m | 3-14wks | 2018 |
|
RNA expression profiling
with selenium |
Selenium regulation of selenoprotein enzyme activity and transcripts. | inbred w/CC8 (8) | m | 3-14wks | 2018 |
|
complete blood count | Hematology. | B6.PWD consomic w/par (28) | both | 9wks | 2006 |
|
metabolic panel | Glucose, bilirubin, blood urea nitrogen, aspartate transaminase (plasma). 4h fast. | B6.PWD consomic w/par (28) | both | 9wks | 2006 |
|
lipid profile | Cholesterol, HDL, triglycerides, free fatty acids. 4h fast, plasma. | B6.PWD consomic w/par (28) | both | 9wks | 2006 |
|
body size and weight | Body weight, body length, body mass index. | B6.PWD consomic w/par (28) | both | 16wks | 2006 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content. | B6.PWD consomic w/par (28) | both | 16wks | 2006 |
|
assisted reproduction | Performance following assisted reproductive technologies. | inbred (10) | f | various | 2006 |
|
body weight
with cocaine |
Body weight | inbred (45) | m | 8-11wks | 2015 |
|
open field test
with cocaine |
Locomotor activity. Baseline (saline) vs. cocaine 20 mg/kg i.p. 30 min test. | inbred (45) | m | 8-11wks | 2015 |
|
open field test
with ovariectomy |
Locomotor activity and exploratory behavior. Mice with ovariectomy surgery vs. controls (sham surgery), 10 min test. | inbred (37) | f | 8-10wks | 2016 |
|
forced swim test
with ovariectomy |
Mice with ovariectomy surgery vs. controls (sham surgery), 6 min test. | inbred (37) | f | 8-10wks | 2016 |
|
open field test
with cocaine |
Locomotor activity. Baseline (saline) vs. cocaine i.p. (several doses). 1.3h and 2.3 h duration. | inbred (15) | both | 8-10wks | 2011 |
|
open field test
with R-6-Br-APB, quinelorane |
Locomotor activity. Baseline (saline) vs. dopamine agonists i.p. (several doses). 3h session. | inbred (15) | both | 8-10wks | 2011 |
|
metabolic panel
with acetaminophen |
Blood urea nitrogen, alanine transaminase, aspartate transaminase (serum), liver enzyme homeostasis. Acetaminophen (several doses) vs. control, several timepoints post-Rx. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
histopathology
with acetaminophen |
Liver histopathology, necrosis after acetaminophen vs. control. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
metabolite quantification
with acetaminophen |
Liver protein homeostasis. Acetaminophen vs. control. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
biomarker quantification
with acetaminophen |
Liver cytochrome isoforms. Acetaminophen vs. control. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
organ weights
with acetaminophen |
Liver weight after acetaminophen (several doses) vs. control. 18h fast. | inbred w/CC7 (37) | m | 8-17wks | 2005 |
|
metabolic panel
with acetaminophen |
Alanine transaminase (serum). Acetaminophen (several doses) vs. control. | inbred (5) | m | 6-8wks | 2005 |
|
metabolite quantification
with acetaminophen |
Glutathione. | inbred (5) | m | 6-8wks | 2005 |
|
drug and metabolite quantification
with acetaminophen |
Acetaminophen metabolite concentrations (serum) and liver protein homeostasis. Baseline vs. acetaminophen (several doses, several timepoints). | inbred (5) | m | 6-8wks | 2005 |
|
histopathology
with acetaminophen |
Liver histopathology, necrosis, injury after acetaminophen vs. control. 18h fast. | inbred (5) | m | 6-8wks | 2005 |
|
biomarker quantification | Fibronectin. | inbred (25) | both | 9wks | 2007 |
|
bottle choice test | Various salt solutions (several concentrations) vs. water. | inbred (28) | m | 9wks | 2001 |
|
body weight | Body weight | inbred (28) | m | 4-12wks | 2001 |
|
intake monitoring | Food intake, water intake. Daily. | inbred (28) | m | 4-12wks | 2001 |
|
body weight | Body weight | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
bottle choice test | Various salt solutions (several concentrations) vs. water. | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
DXA | Body mass, fat mass, lean mass, bone mineral density and content. | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
metabolic panel | Ionized and total blood calcium, blood pH. | inbred w/CC7 (40) | both | 9-15wks | 2002 |
|
elevated plus maze | Exploratory and anxiety-related behaviors. 5 min test. | inbred (16) | m | 6-8wks | 1993 |
|
open field test | Locomotor activity under dim lights vs. bright lights. 5 min test. | inbred (16) | m | 6-8wks | 1993 |
|
monitoring system | Novelty-induced fear test. Eating inhibition due to novelty of environment. 10 min test. | inbred (16) | m | 6-8wks | 1993 |
|
hormone quantification | Corticosterone levels (plasma). Baseline vs. after stress (30 min in restraining cage). | inbred (16) | m | 6-8wks | 1993 |
|
study archive | Brain weight, body weight. | QTL population | both | 2005 | |
|
body weight | Body weight | ILSXISS (43) | both | 8-23wks | 2015 |
|
intake monitoring | Ethanol consumed during 2h availability during dark phase. 4 days/trials with variations. | ILSXISS (43) | both | 8-23wks | 2015 |
|
body weight | Body weight | inbred (21) | both | 6-8wks | 2009 |
|
mineral quantification | Liver mineral levels. Iron, copper, zinc. Iron homeostasis. | inbred (18) | both | 8wks | 2010 |
|
transferrin quantification | Diferric transferrin (plasma). | inbred (18) | both | 8wks | 2010 |
|
open field test | Locomotor, exploratory, and anxiety-related behavior. 5 min test. | inbred (21) | both | 9, 12 wks | 2003 |
|
elevated plus maze | Locomotor, exploratory, and anxiety-related behavior. | inbred (21) | both | 9, 12 wks | 2003 |
|
behavior observation | Wildness scoring during various phenotyping tests. | inbred (21) | both | 10-12wks | 2003 |
|
study archive
with high-fat diet |
Lipids (plasma). Cholesterol, inducibility, triglycerides, atherosclerosis lesions. | QTL population | f | 10-23wks | 2003 |
|
body weight | Body weight | inbred w/CC7 (40) | both | 5-6wks | 2002 |
|
acoustic startle test | Acoustic startle response, prepulse inhibition. | inbred w/CC7 (40) | both | 5-6wks | 2002 |
|
elevated plus maze | Locomotor activity. | inbred (38) | both | 12-14wks | 2010 |
|
open field test | Locomotor activity. | inbred (38) | both | 12-14wks | 2010 |
|
light-dark box | Light-dark test. Anxiety-related behavior. | inbred (38) | both | 12-14wks | 2010 |
|
tail suspension test
with fluoxetine |
Immobility. Fluoxetine-treated vs. control. 5 min test. | inbred (30) | m | 9-11wks | 2011 |
|
open field test
with fluoxetine |
Locomotor activity, exploratory and anxiety-related behavior. Fluoxetine-treated vs. control. 7 min test. | inbred (30) | m | 9-11wks | 2011 |
|
drug and metabolite quantification
with fluoxetine |
Fluoxetine and norfluoxetine concentration (serum) after fluoxetine. | inbred (30) | m | 9-11wks | 2011 |
|
biomarker quantification
with fluoxetine |
Brain tissue survey of 30 biochemical analytes. Fluoxetine-treated vs. control. 21d. | inbred (30) | m | 10-11wks | 2011 |
|
immune cell quantification
with BEZ235, doxorubicin, idarubicin, selumetinib |
In vitro study of 4 cancer chemotherapies (BEZ235, doxorubicin, idarubicin, selumetinib) vs. control. Effect on immune cells. Normalized data. | inbred w/CC7 (36) | m | 10wks | 2015 |
|
study archive
with high-fat diet |
Liver weight, gallbladder and gallstone histopathology. | QTL population | both | 18-20wks | 2002 |
|
study archive
with high-fat diet |
Lipids (plasma), liver weight, gallbladder and gallstone histopathology. | QTL population | both | 6-16wks | 2003 |
|
study archive
with high-fat diet |
Lipids (plasma), liver weight, gallbladder and gallstone histopathology. | QTL population | both | 2005 | |
|
body weight | Body weight | CC RIX (73) | both | 7-13wks | 2020 |
|
inclined screen test | Latency to move all four paws. | CC RIX (73) | both | 7-13wks | 2020 |
|
open field test | Locomotor activity, anxiety, stereotypy. | CC RIX (73) | both | 7-13wks | 2020 |
|
behavior observation | Vacuous chewing, tongue protrusion, jaw tremor. | CC RIX (73) | both | 7-13wks | 2020 |
|
drug and metabolite quantification | Plasma haloperidol concentration. | CC RIX (73) | both | 7-13wks | 2020 |
|
body weight
with arsenic |
Baseline, then after iAs exposure for 26 wks | DO population | m | 4-34 wks | 2022 |
|
intake monitoring
with arsenic |
Food and water consumption, at baseline then at 1 to 4 wk intervals after iAs exposure | DO population | m | 4-34 wks | 2022 |
|
MRI
with arsenic |
Fat and lean tissue mass at baseline, and 12 and 24 wks after iAs exposure | DO population | m | 4-34 wks | 2022 |
|
urinalysis
with arsenic |
Urine volume at baseline, and 12 and 24 wks after iAs exposure | DO population | m | 4-34 wks | 2022 |
|
metabolic panel
with arsenic |
Blood glucose following 6 h fast, and after intraperitoneal glucose injection; at baseline and after iAs exposure | DO population | m | 4-34 wks | 2022 |
|
hormone quantification
with arsenic |
Blood insulin following 6 h fast, and after intraperitoneal glucose injection; at baseline and after iAs exposure | DO population | m | 4-34 wks | 2022 |
|
metabolite quantification
with arsenic |
iAs quantification in urine and liver, at 24 and 26 wks after iAs exposure. IAs speciation evaluated specifically monomethyl-arsenic acid (MMA) and dimethyl-arsenic acid (DMA) | DO population | m | 4-34 wks | 2022 |
|
gait analysis | Aging study, 6mo, 12mo, 18mo. | inbred (31) | both | 26, 52, 78 wks | 2010 |
|
study archive | Circadian behavior. | QTL population | m | 9-34wks | 2011 |
|
study archive | Body weight (several timepoints) and liver weight. | QTL population | both | 2-12wks | 2007 |
|
body weight | Aging study, 6mo, 12mo, and 18mo. | inbred (33) | both | 26, 52, 78 wks | 2007 |
|
hormone quantification | Insulin-like growth factor 1 (serum). Aging study, 6mo, 12mo, and 18mo. | inbred (33) | both | 26, 52, 78 wks | 2007 |
|
colony observation | Life span study. Survival curves. Aging study. | inbred (31) | both | max lifespan | 2007 |
|
metabolic panel | Clinical blood chemistry. Aging study, 6mo, 12mo, 18mo. | inbred (32) | both | 26, 52, 78 wks | 2008 |
|
lipid profile | Cholesterol (HDL). Aging study, 6mo, 12mo, 18mo. 4h fast, plasma. | inbred (32) | both | 26, 52, 78 wks | 2008 |
|
study archive | Plasma levels of P-selectin and soluble vascular cell adhesion molecule-1. | QTL population | f | 18wks | 2008 |
|
glycosylation profile | IgG glycan peaks, relative abundance | CC (111) | both | 4-140wks | 2018 |
|
glycosylation profile | IgG subclasses, relative abundance | CC (95) | both | 20-117wks | 2018 |
|
study archive
with western diet |
Atherosclerosis and glucose homeostasis. Lesions, lipids, glucose, insulin. High-fat, western-style diet. | QTL population | f | <6-18wks | 2012 |
|
body weight | inbred (30) | both | 7-15 wks | 2020 | |
|
intake monitoring | Food and water intake; 2-day test, second day data analyzed during 12:12h light and dark periods. | inbred (30) | both | 7-15 wks | 2020 |
|
monitoring system | Voluntary activity and energy expenditure. 2-day test, second day data analyzed during 12:12h light and dark periods. | inbred (30) | both | 7-15 wks | 2020 |