MPD: Data set: Hadsell2

Hadsell DL, Hadsell LA, Rijnkels M, Carcamo-Bahena Y, Wei J, Williamson P, Grusak MA. In silico mapping of quantitative trait loci (QTL) regulating the milk ionome in mice identifies a milk iron locus on chromosome 1. Mamm Genome. 2018 Oct;29(9-10):632-655. doi: 10.1007/s00335-018-9762-7. Epub 2018 Aug 2. PubMed 30073618

Milk samples from lactating mice (second litter) were analyzed to determine the concentrations of calcium, copper, iron, magnesium, phosphorus, potassium, sodium, sulfur, and zinc.

Procedures conducted:

• mineral quantification

concentrations of various minerals in milk

Hadsell2 downloads
• Download Hadsell2 project data set animal data, as uploaded
• Download Hadsell2 animal data matrix with factor-related expansion applied as necessary
• Download Hadsell2 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Hadsell2 measures:

MA:0002552 mammary gland milk
MP:0020880 abnormal milk calcium level
MP:0020881 abnormal milk copper level
MP:0020882 abnormal milk iron level
MP:0020884 abnormal milk magnesium level
MP:0020886 abnormal milk phosphate level
MP:0020888 abnormal milk potassium level
MP:0020890 abnormal milk sodium level
MP:0020892 abnormal milk sulfate level
MP:0020894 abnormal milk zinc level
VT:0010290 milk calcium amount
VT:0010291 milk potassium amount
VT:0010292 milk sodium amount
VT:0010293 milk phosphorus amount
VT:0010295 milk magnesium amount
VT:0010710 milk copper amount
VT:0010711 milk iron amount
VT:0010714 milk zinc content
VT:0010808 milk sulfur amount

Investigators	Darryl L Hadsell Baylor College of Medicine, Houston, TX
Participants	Hadsell LA, Rijnkels M, Carcamo-Bahena Y, Wei J, Williamson P, Grusak MA
Contact	Darryl L Hadsell dhadsell@bcm.edu Lab web site
Acknowledgements	Funding provided by USDA/ARS cooperative agreement # 250-51000-052
Project type	Phenotype strain survey data set
MPD identifiers	Hadsell2 MPD:1005
Data changelog	No updates/corrections. Initial release date: 11/2019.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Hadsell2:1	Hadsell2	mineral quantification	(none)	milk calcium (Ca) concentration [mM] calcium 110059	inbred	31	f	14-20wks	N=8

Hadsell2:2	Hadsell2	mineral quantification	(none)	milk copper (Cu) concentration [µM] copper 110060	inbred	31	f	14-20wks	N=8

Hadsell2:3	Hadsell2	mineral quantification	(none)	milk iron (Fe) concentration [µM] iron 110061	inbred	31	f	14-20wks	N=8

Hadsell2:4	Hadsell2	mineral quantification	(none)	milk magnesium (Mg) concentration [mM] magnesium 110062	inbred	31	f	14-20wks	N=8

Hadsell2:5	Hadsell2	mineral quantification	(none)	milk potassium (K) concentration [mM] potassium 110063	inbred	31	f	14-20wks	N=8

Hadsell2:6	Hadsell2	mineral quantification	(none)	milk phosphorus (P) concentration [mM] phosphorus 110064	inbred	31	f	14-20wks	N=8

Hadsell2:7	Hadsell2	mineral quantification	(none)	milk sodium (Na) concentration [mM] sodium 110065	inbred	31	f	14-20wks	N=8

Hadsell2:8	Hadsell2	mineral quantification	(none)	milk sulfur (S) concentration [mM] sulfur 110066	inbred	31	f	14-20wks	N=8

Hadsell2:9	Hadsell2	mineral quantification	(none)	milk zinc (Zn) concentration [µM] zinc 110067	inbred	31	f	14-20wks	N=8

Hadsell2: Analysis of milk minerals in 31 inbred strains of mice (2018)