DiCurzio1: Adrenal gland weight and morphology in 64 BXD recombinant inbred strains of mice (2010)

Philip VM, Duvvuru S, Gomero B, Ansah TA, Blaha CD, Cook MN, Hamre KM, Lariviere WR, Matthews DB, Mittleman G, Goldowitz D, Chesler EJ. High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains. Genes Brain Behav. 2010 Mar 1;9(2):129-59. Epub 2009 Sep 22.   PubMed 19958391     FullText

Di Curzio DL, Goldowitz D. The genetic basis of adrenal gland weight and structure in BXD recombinant inbred mice. Mamm Genome. 2011 Apr;22(3-4):209-34. Epub 2011 Feb 24.   PubMed 21347846  


         
Procedures conducted:
• body weight 
• organ weights  Adrenal weight.
• histopathology  Adrenal glands.

DiCurzio1 downloads
• Download DiCurzio1 project data set     animal data, as uploaded
• Download DiCurzio1 animal data matrix     with factor-related expansion applied as necessary
• Download DiCurzio1 strain means, SD, N, etc.     one row per strain/sex/measure
• DiCurzio1 supplementary data
Investigators Domenico L Di Curzio       University of Manitoba,  Winnipeg, Manitoba CANADA
Daniel Goldowitz       University of British Columbia,  Vancouver British Columbia CANADA
ContactDaniel Goldowitz     dang@cmmt.ubc.ca     Lab web site
AcknowledgementsFunding provided by NIH DA020677 and AA016666

Animals used in this study were provided primarily by Oak Ridge National Laboratory.
Project type Phenotype strain survey data set
MPD identifiersDiCurzio1     MPD:366
Data changelog No updates/corrections.       Initial release date: 04/2011.
Formatted citation
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Mice: BXD w/par   66 strains   ♀♂   age 10wks   1 experimental group

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Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
    DiCurzio1 body weight (none) body weight at testing   [g]  bw   36601 BXD w/par 66 both 7-10wks* N=4
    DiCurzio1 organ weights (none) adrenal weights   [mg]  adr_wt   36602     left    right BXD w/par 66 both 7-10wks* N=4
    DiCurzio1 organ weights (none) mean weight of both adrenals   [mg]  adr_wt_ave   36604 BXD w/par 66 both 7-10wks* N=4
    DiCurzio1 organ weights (none) total weight of adrenals adjusted to body weight (x10-3)   [mg]  adr_adj_bw   36605 BXD w/par 66 both 7-10wks* N=4
    DiCurzio1 histopathology (none) adrenal total width, diameter   [µm]  adr_width   36606 BXD w/par 66 both 7-10wks* N=3
    DiCurzio1 histopathology (none) adrenal medulla width   [µm]  adr_medul_width   36607 BXD w/par 66 both 7-10wks* N=3
    DiCurzio1 histopathology (none) adrenal cortex zona glomerulosa thickness   [µm]  adr_glome_width   36608 BXD w/par 66 both 7-10wks* N=3
    DiCurzio1 histopathology (none) adrenal cortex zona intermedia thickness   [µm]  adr_inter_width   36609 BXD w/par 66 both 7-10wks* N=3
    DiCurzio1 histopathology (none) adrenal cortex zona fasciculata thickness   [µm]  adr_fasci_width   36610 BXD w/par 66 both 7-10wks* N=3
    DiCurzio1 histopathology (none) adrenal cortex zona reticularis thickness   [µm]  adr_retic_width   36611 BXD w/par 66 both 7-10wks* N=3
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