Palmer2: Drug study: Measurement of open field activity and methamphetamine-induced locomotor stimulation in C57BL/6J-Chr#A/J/NaJ mouse chromosome substitution panel (2008)

Palmer AA, Verbitsky M, Suresh R, Kamens HM, Reed CL, Li N, Burkhart-Kasch S, McKinnon CS, Belknap JK, Gilliam TC, Phillips TJ. Gene expression differences in mice divergently selected for methamphetamine sensitivity. Mamm Genome. 2005 May;16(5):291-305.   PubMed 16104378  


         
Palmer2 downloads
• Download Palmer2 project data set     animal data, as uploaded
• Download Palmer2 animal data matrix     with factor-related expansion applied as necessary
• Download Palmer2 strain means, SD, N, etc.     one row per strain/sex/measure
Investigators Abraham A Palmer       University of California, San Diego,  San Diego, CA
Participants Bryant CD, Chang H, Zhang J
ContactAbraham A Palmer     aapalmer@ucsd.edu     Lab web site
Project type Phenotype strain survey data set
MPD identifiersPalmer2     MPD:300
Data changelog 1 update/correction.       Initial release date: 11/2008.
Formatted citation
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Procedures conducted:
• open field test  Locomotor activity and habituation. Baseline (saline) vs. methamphetamine 2 mg/kg i.p. 30 min test.

Mice: B6.A consomic w/par   21 strains   ♀♂   age 10wks   1 experimental group

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Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
Sample Size (Avg)
    Palmer2 open field test methamphetamine distance traveled   [cm]  activity_OFT   30001     day 1 control    day 2 control    day 3 Rx B6.A consomic w/par 21 both 7-16wks N=13
    Palmer2 open field test methamphetamine change in activity from day 1 to day 2, habituation   [cm]  habituation_OFT   30004 B6.A consomic w/par 21 both 7-16wks N=14
    Palmer2 open field test methamphetamine change in activity after methamphetamine, day3-day1   [cm]  methactivity1_OFT   30005 B6.A consomic w/par 21 both 7-16wks N=13
    Palmer2 open field test methamphetamine change in activity after methamphetamine and habituation, day3-day2   [cm]  methactivity2_OFT   30006 B6.A consomic w/par 21 both 7-16wks N=13
    Palmer2 colony observation (none) age at test (local parameter)   [wks]  age   30080 B6.A consomic w/par 21 both N=13
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