Loos1: High-throughput phenotyping of avoidance learning in males of 8 inbred strains of mice (2012)

Maroteaux G, Loos M, van der Sluis S, Koopmans B, Aarts E, van Gassen K, Geurts A; NeuroBSIK Mouse Phenomics Consortium, Largaespada DA, Spruijt BM, Stiedl O, Smit AB, Verhage M. High-throughput phenotyping of avoidance learning in mice discriminates different genotypes and identifies a novel gene. Genes Brain Behav. 2012 Oct;11(7):772-84. doi: 10.1111/j.1601-183X.2012.00820.x. Epub 2012 Aug 2.   PubMed 22846151     FullText


         
Procedures conducted:
• home cage monitoring  Locomotor activity, avoidance, sheltering, habituation, preference index, aversion index, over several days.

Loos1 downloads
• Download Loos1 project data set     animal data, as uploaded
• Download Loos1 animal data matrix     with factor-related expansion applied as necessary
• Download Loos1 strain means, SD, N, etc.     one row per strain/sex/measure
• Loos1 supplementary data
Investigators Maarten Loos       Sylics,  Amsterdam NETHERLANDS
G Maroteaux       VU University Amsterdam,  Amsterdam NETHERLANDS
AB Smit       VU University Amsterdam,  Amsterdam NETHERLANDS
M Verhage       VU University Amsterdam,  Amsterdam NETHERLANDS
Participants van der Sluis S, Koopmans B, Aarts E, van Gassen K, Geurts A, Largaespada DA, Spruijt BM, Stiedl O, Neuro-BSIK Mouse Phenomics Consortium
ContactMaarten Loos     maarten.loos@sylics.com     Lab web site
Project type Phenotype strain survey data set
MPD identifiersLoos1     MPD:507
Data changelog No updates/corrections.       Initial release date: 06/2014.
Formatted citation
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Mice: inbred   8 strains   ♂   age 8-19wks   1 experimental group

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Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
Sample Size (Avg)
    Loos1 home cage monitoring (none) cognitive response: entries through preferred vs. non-preferred entrances into shelter  preference   50701     phase (day):    habituation (4)    avoidance learning (5)    avoidance learning (6)    stability of change (7) inbred 8 m 8-19wks N=36
    Loos1 home cage monitoring (none) aversive response: time spent in illuminated vs. non-illuminated shelter  aversive   50705     phase (day):    habituation (4)    avoidance learning (5)    avoidance learning (6)    stability of change (7) inbred 8 m 8-19wks N=36
    Loos1 home cage monitoring (none) distance traveled   [km]  distance   50709     phase (day):    habituation (4)    avoidance learning (5)    avoidance learning (6)    stability of change (7) inbred 8 m 8-19wks N=36
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