HMDPpheno6: Liver metabolite levels: Amino acids in males of 104 strains of the Hybrid Mouse Diversity Panel (HMDP) (2014)

Ghazalpour A, Bennett BJ, Shih D, Che N, Orozco L, Pan C, Hagopian R, He A, Kayne P, Yang WP, Kirchgessner T, Lusis AJ. Genetic regulation of mouse liver metabolite levels. Mol Syst Biol. 2014 May 23;10(5):730. doi: 10.15252/msb.20135004.   PubMed 24860088  


         
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• Download HMDPpheno6 project data set     animal data, as uploaded
• Download HMDPpheno6 animal data matrix     with factor-related expansion applied as necessary
• Download HMDPpheno6 strain means, SD, N, etc.     one row per strain/sex/measure
• HMDPpheno6 supplementary data
No ontology terms have been mapped to HMDPpheno6 measures.
Investigators Anatole Ghazalpour       University of California, Los Angeles,  Los Angeles, CA
Brian J Bennett       University of North Carolina,  Chapel Hill, NC
Luz Orozco       University of California, Los Angeles,  Los Angeles, CA
Aldons J Lusis       University of California, Los Angeles,  Los Angeles, CA
Participants Shih D, Che N, Pan C, Hagopian R, He A, Kayne P, Yang W-P
ContactAnatole Ghazalpour     aghazalp@ucla.edu     Lab web site
Affiliated CenterHybrid Mouse Diversity Panel Group (HMDP)
Part of a series: • Metabolite survey: Amino acids   (this project) HMDPpheno6
• Metabolite survey: Carbs, cofactors, vitamins, energy, xenobiotics   see HMDPpheno7
• Metabolite survey: Lipids (non-lysolipids)   see HMDPpheno8
• Metabolite survey: Lipids (lysolipids)   see HMDPpheno9
• Metabolite survey: Nucleotides, peptides   see HMDPpheno10
AcknowledgementsFunding provided by NIH HL30568, HL28481, HL102223, HG002536, GM07104
Project type Phenotype strain survey data set
MPD identifiersHMDPpheno6     MPD:501
Data changelog No updates/corrections.       Initial release date: 06/2014.
Formatted citation
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Procedures conducted:
• metabolite quantification  Liver metabolic profiling. Molecular measures of amino acids. 16h fast.

Mice: HMDP   106 strains   ♂   age 16wks   1 experimental group

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Data set
Procedure / Protocol
Treatment
Phenotype Measure / Variable (click to view)
Panel
No. of Strains
Sex
Age
Sample Size (Avg)
    HMDPpheno6 metabolite quantification (none) liver alanine (16h fast), relative abundance  Ala   50101 HMDP w/par 106 m 16wks N=1
    HMDPpheno6 metabolite quantification (none) liver asparagine (16h fast), relative abundance  Asn   50102 HMDP w/par 106 m 16wks N=1
    HMDPpheno6 metabolite quantification (none) liver aspartate (16h fast), relative abundance  Asp   50103 HMDP w/par 106 m 16wks N=1
    HMDPpheno6 metabolite quantification (none) liver beta-alanine (16h fast), relative abundance  beta_Ala   50104 HMDP w/par 106 m 16wks N=1
    HMDPpheno6 metabolite quantification (none) liver N-acetylasparagine (16h fast), relative abundance  acetyl_Asn   50105 HMDP w/par 103 m 16wks N=1
    HMDPpheno6 metabolite quantification (none) liver N-acetylalanine (16h fast), relative abundance  acetyl_Ala   50106 HMDP w/par 104 m 16wks N=1
    HMDPpheno6 metabolite quantification (none) liver 2-aminobutyrate (16h fast), relative abundance  aminobutyrate   50107 HMDP w/par 106 m 16wks N=1
    HMDPpheno6 metabolite quantification (none) liver creatine (16h fast), relative abundance  creatine   50108 HMDP w/par 106 m 16wks N=1
    HMDPpheno6 metabolite quantification (none) liver 2-hydroxybutyrate (AHB) (16h fast), relative abundance  AHB   50109 HMDP w/par 99 m 16wks N=1
    HMDPpheno6 metabolite quantification (none) liver cysteine (16h fast), relative abundance  Cys   50110 HMDP w/par 106 m 16wks N=1
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