Project measure / variable:   HMDPpheno6   acetyl_Met

ID, description, units MPD:50115   acetyl_Met   liver N-acetylmethionine (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


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  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver N-acetylmethionine (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means22692   None
Median of the strain means21578   None
SD of the strain means± 7618
Coefficient of variation (CV)0.336
Min–max range of strain means10778   –   48140   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 5199876304.3091 247613157.3481 8.1414 < 0.0001
Residuals 34 1034073858.8922 30413937.0262


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 28469.0 0.0   1   0.0 0.0 28469.0, 28469.0 0.76
A/J m 22636.0 9389.0   2   6639.0 0.415 15997.0, 29275.0 -0.01
AKR/J m 22785.0 0.0   1   0.0 0.0 22785.0, 22785.0 0.01
AXB10/PgnJ m 17847.0 0.0   1   0.0 0.0 17847.0, 17847.0 -0.64
AXB12/PgnJ m 14088.0 0.0   1   0.0 0.0 14088.0, 14088.0 -1.13
AXB13/PgnJ m 27006.0 0.0   1   0.0 0.0 27006.0, 27006.0 0.57
AXB15/PgnJ m 17627.0 0.0   1   0.0 0.0 17627.0, 17627.0 -0.66
AXB19a/PgnJ m 25207.0 0.0   1   0.0 0.0 25207.0, 25207.0 0.33
AXB19b/PgnJ m 30241.0 5228.0   2   3697.0 0.173 26545.0, 33938.0 0.99
AXB19/PgnJ m 20825.0 0.0   1   0.0 0.0 20825.0, 20825.0 -0.25
AXB1/PgnJ m 18324.0 0.0   1   0.0 0.0 18324.0, 18324.0 -0.57
AXB23/PgnJ m 36601.0 0.0   1   0.0 0.0 36601.0, 36601.0 1.83
AXB24/PgnJ m 11757.0 884.0   2   625.0 0.0752 11132.0, 12382.0 -1.44
AXB2/PgnJ m 28083.0 0.0   1   0.0 0.0 28083.0, 28083.0 0.71
AXB4/PgnJ m 21580.0 0.0   1   0.0 0.0 21580.0, 21580.0 -0.15
AXB5/PgnJ m 22865.0 0.0   1   0.0 0.0 22865.0, 22865.0 0.02
AXB6/PgnJ m 29163.0 0.0   1   0.0 0.0 29163.0, 29163.0 0.85
AXB8/PgnJ m 25551.0 0.0   1   0.0 0.0 25551.0, 25551.0 0.38
BALB/cJ m 33228.0 3735.0   3 2156.0 0.112 28946.0, 35814.0 1.38
BTBR T+ Itpr3tf/J m 26608.0 0.0   1   0.0 0.0 26608.0, 26608.0 0.51
BUB/BnJ m 22633.0 0.0   1   0.0 0.0 22633.0, 22633.0 -0.01
BXA11/PgnJ m 11944.0 0.0   1   0.0 0.0 11944.0, 11944.0 -1.41
BXA12/PgnJ m 13736.0 0.0   1   0.0 0.0 13736.0, 13736.0 -1.18
BXA13/PgnJ m 30525.0 0.0   1   0.0 0.0 30525.0, 30525.0 1.03
BXA14/PgnJ m 26272.0 0.0   1   0.0 0.0 26272.0, 26272.0 0.47
BXA16/PgnJ m 21707.0 3909.0   2   2764.0 0.18 18943.0, 24471.0 -0.13
BXA1/PgnJ m 15953.0 0.0   1   0.0 0.0 15953.0, 15953.0 -0.88
BXA24/PgnJ m 22806.0 0.0   1   0.0 0.0 22806.0, 22806.0 0.02
BXA25/PgnJ m 17421.0 0.0   1   0.0 0.0 17421.0, 17421.0 -0.69
BXA26/PgnJ m 23682.0 0.0   1   0.0 0.0 23682.0, 23682.0 0.13
BXA2/PgnJ m 33044.0 0.0   1   0.0 0.0 33044.0, 33044.0 1.36
BXA4/PgnJ m 13519.0 0.0   1   0.0 0.0 13519.0, 13519.0 -1.2
BXA7/PgnJ m 38269.0 0.0   1   0.0 0.0 38269.0, 38269.0 2.04
BXA8/PgnJ m 19493.0 0.0   1   0.0 0.0 19493.0, 19493.0 -0.42
BXD11/TyJ m 16250.0 0.0   1   0.0 0.0 16250.0, 16250.0 -0.85
BXD12/TyJ m 15573.0 0.0   1   0.0 0.0 15573.0, 15573.0 -0.93
BXD13/TyJ m 15595.0 0.0   1   0.0 0.0 15595.0, 15595.0 -0.93
BXD14/TyJ m 17782.0 0.0   1   0.0 0.0 17782.0, 17782.0 -0.64
BXD15/TyJ m 13454.0 0.0   1   0.0 0.0 13454.0, 13454.0 -1.21
BXD18/TyJ m 23359.0 0.0   1   0.0 0.0 23359.0, 23359.0 0.09
BXD19/TyJ m 20699.0 440.0   2   311.0 0.0213 20388.0, 21010.0 -0.26
BXD1/TyJ m 23208.0 0.0   1   0.0 0.0 23208.0, 23208.0 0.07
BXD20/TyJ m 20944.0 0.0   1   0.0 0.0 20944.0, 20944.0 -0.23
BXD21/TyJ m 10778.0 0.0   1   0.0 0.0 10778.0, 10778.0 -1.56
BXD22/TyJ m 25209.0 0.0   1   0.0 0.0 25209.0, 25209.0 0.33
BXD24/TyJ m 14517.0 0.0   1   0.0 0.0 14517.0, 14517.0 -1.07
BXD24/TyJ-Cep290rd16/J m 13872.0 0.0   1   0.0 0.0 13872.0, 13872.0 -1.16
BXD28/TyJ m 14667.0 3465.0   2   2450.0 0.236 12217.0, 17118.0 -1.05
BXD29-Tlr4lps-2J/J m 19522.0 0.0   1   0.0 0.0 19522.0, 19522.0 -0.42
BXD2/TyJ m 20046.0 0.0   1   0.0 0.0 20046.0, 20046.0 -0.35
BXD32/TyJ m 21208.0 0.0   1   0.0 0.0 21208.0, 21208.0 -0.19
BXD33/TyJ m 23187.0 0.0   1   0.0 0.0 23187.0, 23187.0 0.07
BXD34/TyJ m 18812.0 0.0   1   0.0 0.0 18812.0, 18812.0 -0.51
BXD36/TyJ m 11890.0 0.0   1   0.0 0.0 11890.0, 11890.0 -1.42
BXD38/TyJ m 18806.0 0.0   1   0.0 0.0 18806.0, 18806.0 -0.51
BXD39/TyJ m 17722.0 0.0   1   0.0 0.0 17722.0, 17722.0 -0.65
BXD40/TyJ m 20706.0 0.0   1   0.0 0.0 20706.0, 20706.0 -0.26
BXD42/TyJ m 18261.0 0.0   1   0.0 0.0 18261.0, 18261.0 -0.58
BXD5/TyJ m 17817.0 0.0   1   0.0 0.0 17817.0, 17817.0 -0.64
BXD6/TyJ m 23127.0 0.0   1   0.0 0.0 23127.0, 23127.0 0.06
BXD8/TyJ m 24732.0 0.0   1   0.0 0.0 24732.0, 24732.0 0.27
BXD9/TyJ m 15245.0 0.0   1   0.0 0.0 15245.0, 15245.0 -0.98
BXH10/TyJ m 12043.0 0.0   1   0.0 0.0 12043.0, 12043.0 -1.4
BXH19/TyJ m 29971.0 0.0   1   0.0 0.0 29971.0, 29971.0 0.96
BXH20/KccJ m 19939.0 0.0   1   0.0 0.0 19939.0, 19939.0 -0.36
BXH22/KccJ m 28442.0 0.0   1   0.0 0.0 28442.0, 28442.0 0.75
BXH2/TyJ m 23808.0 0.0   1   0.0 0.0 23808.0, 23808.0 0.15
BXH4/TyJ m 18851.0 2796.0   2   1977.0 0.148 16874.0, 20828.0 -0.5
BXH6/TyJ m 25305.0 0.0   1   0.0 0.0 25305.0, 25305.0 0.34
BXH7/TyJ m 13316.0 0.0   1   0.0 0.0 13316.0, 13316.0 -1.23
BXH8/TyJ m 21495.0 0.0   1   0.0 0.0 21495.0, 21495.0 -0.16
BXH9/TyJ m 19514.0 0.0   1   0.0 0.0 19514.0, 19514.0 -0.42
C3H/HeJ m 27899.0 4890.0   2   3458.0 0.175 24441.0, 31357.0 0.68
C57BL/6J m 27214.0 4519.0   5 2021.0 0.166 23677.0, 34411.0 0.59
C57L/J m 12404.0 0.0   1   0.0 0.0 12404.0, 12404.0 -1.35
C58/J m 23853.0 0.0   1   0.0 0.0 23853.0, 23853.0 0.15
CAST/EiJ m 25409.0 0.0   1   0.0 0.0 25409.0, 25409.0 0.36
CBA/J m 19831.0 0.0   1   0.0 0.0 19831.0, 19831.0 -0.38
CE/J m 25313.0 0.0   1   0.0 0.0 25313.0, 25313.0 0.34
CXB11/HiAJ m 16244.0 2500.0   2   1768.0 0.154 14476.0, 18011.0 -0.85
CXB12/HiAJ m 45096.0 8371.0   2   5919.0 0.186 39177.0, 51015.0 2.94
CXB13/HiAJ m 29707.0 7655.0   3 4420.0 0.258 25210.0, 38546.0 0.92
CXB1/ByJ m 29898.0 3351.0   3 1935.0 0.112 26580.0, 33280.0 0.95
CXB2/ByJ m 33547.0 8339.0   3 4814.0 0.249 26463.0, 42737.0 1.42
CXB3/ByJ m 31663.0 5225.0   2   3695.0 0.165 27968.0, 35358.0 1.18
CXB4/ByJ m 15419.0 449.0   2   317.0 0.0291 15102.0, 15737.0 -0.95
CXB6/ByJ m 42323.0 5511.0   3 3182.0 0.13 36120.0, 46654.0 2.58
CXB7/ByJ m 42174.0 3334.0   2   2358.0 0.0791 39817.0, 44532.0 2.56
CXB8/HiAJ m 48140.0 9724.0   3 5614.0 0.202 38256.0, 57695.0 3.34
CXB9/HiAJ m 36805.0 6074.0   3 3507.0 0.165 30090.0, 41917.0 1.85
DBA/2J m 23203.0 3252.0   4 1626.0 0.14 20582.0, 27926.0 0.07
FVB/NJ m 23424.0 0.0   1   0.0 0.0 23424.0, 23424.0 0.1
I/LnJ m 17506.0 0.0   1   0.0 0.0 17506.0, 17506.0 -0.68
KK/HlJ m 21577.0 0.0   1   0.0 0.0 21577.0, 21577.0 -0.15
LG/J m 15379.0 0.0   1   0.0 0.0 15379.0, 15379.0 -0.96
LP/J m 17622.0 0.0   1   0.0 0.0 17622.0, 17622.0 -0.67
MA/MyJ m 19750.0 0.0   1   0.0 0.0 19750.0, 19750.0 -0.39
NOD/ShiLtJ m 33024.0 0.0   1   0.0 0.0 33024.0, 33024.0 1.36
NON/ShiLtJ m 31989.0 0.0   1   0.0 0.0 31989.0, 31989.0 1.22
NZW/LacJ m 22013.0 0.0   1   0.0 0.0 22013.0, 22013.0 -0.09
PL/J m 21564.0 0.0   1   0.0 0.0 21564.0, 21564.0 -0.15
RIIIS/J m 12173.0 0.0   1   0.0 0.0 12173.0, 12173.0 -1.38
SEA/GnJ m 31075.0 0.0   1   0.0 0.0 31075.0, 31075.0 1.1
SJL/J m 13632.0 0.0   1   0.0 0.0 13632.0, 13632.0 -1.19
SM/J m 26678.0 0.0   1   0.0 0.0 26678.0, 26678.0 0.52
SWR/J m 20589.0 0.0   1   0.0 0.0 20589.0, 20589.0 -0.28


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 22635.95 3899.6113 30560.9137 14710.9863
AXB19b/PgnJ m 30241.45 3899.6113 38166.4137 22316.4863
AXB24/PgnJ m 11757.15 3899.6113 19682.1137 3832.1863
BALB/cJ m 33228.4 3184.0193 39699.1058 26757.6942
BXA16/PgnJ m 21707.2 3899.6113 29632.1637 13782.2363
BXD19/TyJ m 20699.25 3899.6113 28624.2137 12774.2863
BXD28/TyJ m 14667.45 3899.6113 22592.4137 6742.4863
BXH4/TyJ m 18851.3 3899.6113 26776.2637 10926.3363
C3H/HeJ m 27898.85 3899.6113 35823.8137 19973.8863
C57BL/6J m 27213.98 2466.3308 32226.1671 22201.7929
CXB11/HiAJ m 16243.65 3899.6113 24168.6137 8318.6863
CXB12/HiAJ m 45096.3 3899.6113 53021.2637 37171.3363
CXB13/HiAJ m 29707.0333 3184.0193 36177.7391 23236.3276
CXB1/ByJ m 29897.9 3184.0193 36368.6058 23427.1942
CXB2/ByJ m 33547.3333 3184.0193 40018.0391 27076.6276
CXB3/ByJ m 31662.65 3899.6113 39587.6137 23737.6863
CXB4/ByJ m 15419.45 3899.6113 23344.4137 7494.4863
CXB6/ByJ m 42323.0 3184.0193 48793.7058 35852.2942
CXB7/ByJ m 42174.45 3899.6113 50099.4137 34249.4863
CXB8/HiAJ m 48139.6667 3184.0193 54610.3724 41668.9609
CXB9/HiAJ m 36804.7667 3184.0193 43275.4724 30334.0609
DBA/2J m 23202.925 2757.4416 28806.7206 17599.1294




  GWAS USING LINEAR MIXED MODELS