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Project measure / variable:   HMDPpheno6   kynurenine

ID, description, units MPD:50154   kynurenine   liver kynurenine (16h fast), relative abundance    
Data set, strains HMDPpheno6   HMDP w/par   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


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  STRAIN COMPARISON PLOT
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HMDPpheno6 - liver kynurenine (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means258171   None
Median of the strain means215302   None
SD of the strain means± 151326
Coefficient of variation (CV)0.586
Min–max range of strain means83208   –   928236   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 1975742242287.3 94082963918.443 1.6634 0.091
Residuals 34 1923094075340.25 56561590451.1838


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 314854.0 0.0   1   0.0 0.0 314854.0, 314854.0 0.37
A/J m 204535.0 3171.0   2   2242.0 0.0155 202293.0, 206777.0 -0.35
AKR/J m 172808.0 0.0   1   0.0 0.0 172808.0, 172808.0 -0.56
AXB10/PgnJ m 205086.0 0.0   1   0.0 0.0 205086.0, 205086.0 -0.35
AXB12/PgnJ m 214835.0 0.0   1   0.0 0.0 214835.0, 214835.0 -0.29
AXB13/PgnJ m 160104.0 0.0   1   0.0 0.0 160104.0, 160104.0 -0.65
AXB15/PgnJ m 154251.0 0.0   1   0.0 0.0 154251.0, 154251.0 -0.69
AXB19a/PgnJ m 496396.0 0.0   1   0.0 0.0 496396.0, 496396.0 1.57
AXB19b/PgnJ m 404316.0 57841.0   2   40900.0 0.143 363416.0, 445216.0 0.97
AXB19/PgnJ m 419919.0 0.0   1   0.0 0.0 419919.0, 419919.0 1.07
AXB1/PgnJ m 657013.0 0.0   1   0.0 0.0 657013.0, 657013.0 2.64
AXB23/PgnJ m 149370.0 0.0   1   0.0 0.0 149370.0, 149370.0 -0.72
AXB24/PgnJ m 91966.0 41851.0   2   29593.0 0.455 62374.0, 121559.0 -1.1
AXB2/PgnJ m 631587.0 0.0   1   0.0 0.0 631587.0, 631587.0 2.47
AXB4/PgnJ m 445260.0 0.0   1   0.0 0.0 445260.0, 445260.0 1.24
AXB5/PgnJ m 185334.0 0.0   1   0.0 0.0 185334.0, 185334.0 -0.48
AXB6/PgnJ m 310583.0 0.0   1   0.0 0.0 310583.0, 310583.0 0.35
AXB8/PgnJ m 415219.0 0.0   1   0.0 0.0 415219.0, 415219.0 1.04
BALB/cJ m 447497.0 89877.0   3 51891.0 0.201 343894.0, 504565.0 1.25
BTBR T+ Itpr3tf/J m 133960.0 0.0   1   0.0 0.0 133960.0, 133960.0 -0.82
BUB/BnJ m 297318.0 0.0   1   0.0 0.0 297318.0, 297318.0 0.26
BXA11/PgnJ m 96637.0 0.0   1   0.0 0.0 96637.0, 96637.0 -1.07
BXA12/PgnJ m 294094.0 0.0   1   0.0 0.0 294094.0, 294094.0 0.24
BXA13/PgnJ m 228108.0 0.0   1   0.0 0.0 228108.0, 228108.0 -0.2
BXA14/PgnJ m 368565.0 0.0   1   0.0 0.0 368565.0, 368565.0 0.73
BXA16/PgnJ m 298142.0 230068.0   2   162683.0 0.772 135459.0, 460825.0 0.26
BXA1/PgnJ m 118416.0 0.0   1   0.0 0.0 118416.0, 118416.0 -0.92
BXA24/PgnJ m 276195.0 0.0   1   0.0 0.0 276195.0, 276195.0 0.12
BXA25/PgnJ m 172758.0 0.0   1   0.0 0.0 172758.0, 172758.0 -0.56
BXA26/PgnJ m 224935.0 0.0   1   0.0 0.0 224935.0, 224935.0 -0.22
BXA2/PgnJ m 186130.0 0.0   1   0.0 0.0 186130.0, 186130.0 -0.48
BXA4/PgnJ m 267751.0 0.0   1   0.0 0.0 267751.0, 267751.0 0.06
BXA7/PgnJ m 192122.0 0.0   1   0.0 0.0 192122.0, 192122.0 -0.44
BXA8/PgnJ m 221672.0 0.0   1   0.0 0.0 221672.0, 221672.0 -0.24
BXD11/TyJ m 236172.0 0.0   1   0.0 0.0 236172.0, 236172.0 -0.15
BXD12/TyJ m 189098.0 0.0   1   0.0 0.0 189098.0, 189098.0 -0.46
BXD13/TyJ m 175618.0 0.0   1   0.0 0.0 175618.0, 175618.0 -0.55
BXD14/TyJ m 258856.0 0.0   1   0.0 0.0 258856.0, 258856.0 0.0
BXD15/TyJ m 226464.0 0.0   1   0.0 0.0 226464.0, 226464.0 -0.21
BXD18/TyJ m 83938.0 0.0   1   0.0 0.0 83938.0, 83938.0 -1.15
BXD19/TyJ m 183274.0 99429.0   2   70307.0 0.543 112968.0, 253581.0 -0.49
BXD1/TyJ m 100239.0 0.0   1   0.0 0.0 100239.0, 100239.0 -1.04
BXD20/TyJ m 317652.0 0.0   1   0.0 0.0 317652.0, 317652.0 0.39
BXD21/TyJ m 89154.0 0.0   1   0.0 0.0 89154.0, 89154.0 -1.12
BXD22/TyJ m 160159.0 0.0   1   0.0 0.0 160159.0, 160159.0 -0.65
BXD24/TyJ m 128959.0 0.0   1   0.0 0.0 128959.0, 128959.0 -0.85
BXD24/TyJ-Cep290rd16/J m 212772.0 0.0   1   0.0 0.0 212772.0, 212772.0 -0.3
BXD28/TyJ m 145140.0 63550.0   2   44936.0 0.438 100203.0, 190076.0 -0.75
BXD29-Tlr4lps-2J/J m 191552.0 0.0   1   0.0 0.0 191552.0, 191552.0 -0.44
BXD2/TyJ m 215769.0 0.0   1   0.0 0.0 215769.0, 215769.0 -0.28
BXD32/TyJ m 376182.0 0.0   1   0.0 0.0 376182.0, 376182.0 0.78
BXD33/TyJ m 324362.0 0.0   1   0.0 0.0 324362.0, 324362.0 0.44
BXD34/TyJ m 239453.0 0.0   1   0.0 0.0 239453.0, 239453.0 -0.12
BXD36/TyJ m 131863.0 0.0   1   0.0 0.0 131863.0, 131863.0 -0.83
BXD38/TyJ m 554219.0 0.0   1   0.0 0.0 554219.0, 554219.0 1.96
BXD39/TyJ m 89339.0 0.0   1   0.0 0.0 89339.0, 89339.0 -1.12
BXD40/TyJ m 207388.0 0.0   1   0.0 0.0 207388.0, 207388.0 -0.34
BXD42/TyJ m 84734.0 0.0   1   0.0 0.0 84734.0, 84734.0 -1.15
BXD5/TyJ m 192491.0 0.0   1   0.0 0.0 192491.0, 192491.0 -0.43
BXD6/TyJ m 223794.0 0.0   1   0.0 0.0 223794.0, 223794.0 -0.23
BXD8/TyJ m 140841.0 0.0   1   0.0 0.0 140841.0, 140841.0 -0.78
BXD9/TyJ m 132501.0 0.0   1   0.0 0.0 132501.0, 132501.0 -0.83
BXH10/TyJ m 354862.0 0.0   1   0.0 0.0 354862.0, 354862.0 0.64
BXH19/TyJ m 202673.0 0.0   1   0.0 0.0 202673.0, 202673.0 -0.37
BXH20/KccJ m 151581.0 0.0   1   0.0 0.0 151581.0, 151581.0 -0.7
BXH22/KccJ m 144375.0 0.0   1   0.0 0.0 144375.0, 144375.0 -0.75
BXH2/TyJ m 221938.0 0.0   1   0.0 0.0 221938.0, 221938.0 -0.24
BXH4/TyJ m 201208.0 27496.0   2   19443.0 0.137 181765.0, 220650.0 -0.38
BXH6/TyJ m 392702.0 0.0   1   0.0 0.0 392702.0, 392702.0 0.89
BXH7/TyJ m 107345.0 0.0   1   0.0 0.0 107345.0, 107345.0 -1.0
BXH8/TyJ m 239122.0 0.0   1   0.0 0.0 239122.0, 239122.0 -0.13
BXH9/TyJ m 193916.0 0.0   1   0.0 0.0 193916.0, 193916.0 -0.42
C3H/HeJ m 235192.0 56097.0   2   39666.0 0.239 195525.0, 274858.0 -0.15
C57BL/6J m 637556.0 149314.0   5 66775.0 0.234 393372.0, 761498.0 2.51
C57L/J m 183018.0 0.0   1   0.0 0.0 183018.0, 183018.0 -0.5
C58/J m 928236.0 0.0   1   0.0 0.0 928236.0, 928236.0 4.43
CAST/EiJ m 83208.0 0.0   1   0.0 0.0 83208.0, 83208.0 -1.16
CBA/J m 122602.0 0.0   1   0.0 0.0 122602.0, 122602.0 -0.9
CE/J m 349477.0 0.0   1   0.0 0.0 349477.0, 349477.0 0.6
CXB11/HiAJ m 157062.0 64630.0   2   45700.0 0.411 111361.0, 202762.0 -0.67
CXB12/HiAJ m 178876.0 15468.0   2   10938.0 0.0865 167939.0, 189814.0 -0.52
CXB13/HiAJ m 763511.0 839291.0   3 484565.0 1.1 178882.0, 1725202.0 3.34
CXB1/ByJ m 247514.0 34658.0   3 20010.0 0.14 218142.0, 285740.0 -0.07
CXB2/ByJ m 435417.0 300803.0   3 173669.0 0.691 217057.0, 778524.0 1.17
CXB3/ByJ m 274676.0 59464.0   2   42047.0 0.216 232629.0, 316724.0 0.11
CXB4/ByJ m 158082.0 86952.0   2   61484.0 0.55 96597.0, 219566.0 -0.66
CXB6/ByJ m 369142.0 138162.0   3 79768.0 0.374 240442.0, 515137.0 0.73
CXB7/ByJ m 173584.0 38275.0   2   27064.0 0.22 146520.0, 200648.0 -0.56
CXB8/HiAJ m 384544.0 211055.0   3 121852.0 0.549 253048.0, 627988.0 0.84
CXB9/HiAJ m 165903.0 46752.0   3 26992.0 0.282 123494.0, 216036.0 -0.61
DBA/2J m 90089.0 19087.0   4 9543.0 0.212 64278.0, 108733.0 -1.11
FVB/NJ m 325097.0 0.0   1   0.0 0.0 325097.0, 325097.0 0.44
I/LnJ m 313317.0 0.0   1   0.0 0.0 313317.0, 313317.0 0.36
KK/HlJ m 303977.0 0.0   1   0.0 0.0 303977.0, 303977.0 0.3
LG/J m 252780.0 0.0   1   0.0 0.0 252780.0, 252780.0 -0.04
LP/J m 257933.0 0.0   1   0.0 0.0 257933.0, 257933.0 0.0
MA/MyJ m 92562.0 0.0   1   0.0 0.0 92562.0, 92562.0 -1.09
NOD/ShiLtJ m 258184.0 0.0   1   0.0 0.0 258184.0, 258184.0 0.0
NON/ShiLtJ m 457476.0 0.0   1   0.0 0.0 457476.0, 457476.0 1.32
NZW/LacJ m 152289.0 0.0   1   0.0 0.0 152289.0, 152289.0 -0.7
PL/J m 380065.0 0.0   1   0.0 0.0 380065.0, 380065.0 0.81
RIIIS/J m 170858.0 0.0   1   0.0 0.0 170858.0, 170858.0 -0.58
SEA/GnJ m 167423.0 0.0   1   0.0 0.0 167423.0, 167423.0 -0.6
SJL/J m 333395.0 0.0   1   0.0 0.0 333395.0, 333395.0 0.5
SM/J m 138576.0 0.0   1   0.0 0.0 138576.0, 138576.0 -0.79
SWR/J m 545034.0 0.0   1   0.0 0.0 545034.0, 545034.0 1.9


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 204534.9 168168.9485 546295.3221 0.0
AXB19b/PgnJ m 404315.6 168168.9485 746076.0221 62555.1779
AXB24/PgnJ m 91966.4 168168.9485 433726.8221 0.0
BALB/cJ m 447497.4667 137309.3714 726543.6828 168451.2505
BXA16/PgnJ m 298142.0 168168.9485 639902.4221 0.0
BXD19/TyJ m 183274.5 168168.9485 525034.9221 0.0
BXD28/TyJ m 145139.7 168168.9485 486900.1221 0.0
BXH4/TyJ m 201207.7 168168.9485 542968.1221 0.0
C3H/HeJ m 235191.75 168168.9485 576952.1721 0.0
C57BL/6J m 637555.58 106359.3818 853703.8496 421407.3104
CXB11/HiAJ m 157061.5 168168.9485 498821.9221 0.0
CXB12/HiAJ m 178876.35 168168.9485 520636.7721 0.0
CXB13/HiAJ m 763510.6333 137309.3714 1042556.8495 484464.4172
CXB1/ByJ m 247514.1 137309.3714 526560.3162 0.0
CXB2/ByJ m 435417.0667 137309.3714 714463.2828 156370.8505
CXB3/ByJ m 274676.35 168168.9485 616436.7721 0.0
CXB4/ByJ m 158081.5 168168.9485 499841.9221 0.0
CXB6/ByJ m 369142.4333 137309.3714 648188.6495 90096.2172
CXB7/ByJ m 173584.15 168168.9485 515344.5721 0.0
CXB8/HiAJ m 384544.3333 137309.3714 663590.5495 105498.1172
CXB9/HiAJ m 165902.8 137309.3714 444949.0162 0.0
DBA/2J m 90089.225 118913.4038 331750.337 0.0




  GWAS USING LINEAR MIXED MODELS