4-phenylbutyrate: Increases lifespan in flies and has major benefits in mouse models of neurodegenerative disease; reduces inflammation due to aging.

astaxanthin: Naturally occurring xanthophyll carotenoid that is an efficient Nrf2 (Nuclear factor erythroid 2-related factor 2) activator with potent anti-oxidant activity. [Wikipedia article]

dimethyl fumarate: Nrf2 (Nuclear factor erythroid 2-related factor 2) stimulator which increases the production of mitochondria and reduces inflammation.

meclizine: Has central anticholinergic actions and binds to mTOR and inhibits mTORC1. [Wikipedia article]

mycophenolic acid: FDA-approved drug to retard organ transplant rejection; used to treat autoimmune diseases. [Wikipedia article]

SG1002: Slowly releases hydrogen sulfide which has numerous beneficial biological effects, including lifespan extension in C. elegans.