MPD: Data set: Chen1

Chen YG, Tsaih SW, Serreze DV. Genetic control of murine invariant natural killer T-cell development dynamically differs dependent on the examined tissue type. Genes Immun. 2012 Feb;13(2):164-74. doi: 10.1038/gene.2011.68. Epub 2011 Sep 22. PubMed 21938016 FullText

Procedures conducted:

• immune cell quantification

Natural killer T cells in peripheral blood, spleen, thymus.

Chen1 downloads
• Download Chen1 project data set animal data, as uploaded
• Download Chen1 animal data matrix with factor-related expansion applied as necessary
• Download Chen1 strain means, SD, N, etc. one row per strain/sex/measure

Ontology terms mapped to Chen1 measures:

Investigators	Yi-Guang Chen Medical College of Wisconsin, Milwaukee, WI David V Serreze The Jackson Laboratory, Bar Harbor, ME
Participants	Tsaih SW
Contact	Yi-Guang Chen yichen@mcw.edu Lab web site
Acknowledgements	Funding provided by NIH DK46266, DK51090, DK077443
Project type	Phenotype strain survey data set
MPD identifiers	Chen1 MPD:523
Data changelog	No updates/corrections. Initial release date: 10/2014.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	No. of Strains	Sex	Age	Sample Size (Avg)
Chen1:1	Chen1	immune cell quantification	(none)	percentage of total TCRβ+ cells that are invariant NK T cells, peripheral blood [%] pct_iNKT_T_pb 52301	inbred	38	m	8-10wks	N=4

Chen1:2	Chen1	immune cell quantification	(none)	percentage of invariant NK T cells that express CD4, peripheral blood [%] pct_iNKT_CD4_pb 52302	inbred	34	m	8-10wks	N=4

Chen1:3	Chen1	immune cell quantification	(none)	percentage of total TCRβ+ cells that are invariant NK T cells, spleen [%] pct_iNKT_T_spleen 52303	inbred	38	m	8-10wks	N=4

Chen1:4	Chen1	immune cell quantification	(none)	percentage of invariant NK T cells that express CD4, spleen [%] pct_iNKT_CD4_spleen 52304	inbred	35	m	8-10wks	N=4

Chen1:5	Chen1	immune cell quantification	(none)	peripheral blood to spleen ratio of invariant NK T cells [ratio] iNKT_pb_spl_ratio 52305	inbred	38	m	8-10wks	N=4

Chen1:6	Chen1	immune cell quantification	(none)	percentage of total TCRβ^hi cells that are invariant NK T cells, thymus [%] pct_iNKT_T_thymus 52306	inbred	38	m	8-10wks	N=4

Chen1:7	Chen1	immune cell quantification	(none)	percentage of invariant NK T cells that express CD4, thymus [%] pct_iNKT_CD4_thymus 52307	inbred	35	m	8-10wks	N=4

Chen1:8	Chen1	immune cell quantification	(none)	peripheral blood to thymus ratio of invariant NK T cells [ratio] iNKT_pb_thy_ratio 52308	inbred	38	m	8-10wks	N=4

Chen1: Invariant natural killer T-cells in peripheral blood, spleen, and thymus of 38 inbred strains of mice (2011)