MPD: Project measures / variables set: GMC16 CHOL

Project measures / variables set: GMC16 CHOL

ID, description, units	MPD:56546 CHOL total cholesterol (plasma CHOL) [mmol/L]
Measures	• age 16-17wks • 20-21wks
Data set, strains	GMC16 inbred w/CC8 8 strains sex: both
Procedure	lipid profile
Comparison	multiple cohorts measured at two age timepoints
Ontology mappings	VT:0000180 blood cholesterol amount MA:0002501 plasma MP:0000180 abnormal circulating cholesterol level

Values Means Δ Means Z-scores

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GMC16 - total cholesterol (plasma CHOL)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
age	1	4.742	4.742	10.5891	0.0015
sex	1	6.5376	6.5376	14.5988	0.0002
strain	4	318.656	79.664	177.8943	< 0.0001
age:sex	1	0.7648	0.7648	1.7078	0.1936
age:strain	4	8.2259	2.0565	4.5922	0.0017
sex:strain	4	0.5327	0.1332	0.2974	0.8792
age:sex:strain	4	2.6912	0.6728	1.5024	0.2053
Residuals	128	57.3205	0.4478

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
GMC16	56546	lipid profile	(none)	total cholesterol (plasma CHOL) [mmol/L] at age 16-17wks CHOL_17	inbred w/CC8	7	both	16-17wks
GMC16	56547	lipid profile	(none)	total cholesterol (plasma CHOL) [mmol/L] at age 20-21wks CHOL_21	inbred w/CC8	8	both	20-21wks