Project measure / variable:   GMC16   CHOL_17

ID, description, units MPD:56546   CHOL_17   total cholesterol (plasma CHOL)   [mmol/L]  at age 16-17wks  
Data set, strains GMC16   inbred w/CC8   7 strains     sex: both     age: 16-17wks
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  STRAIN COMPARISON PLOT
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GMC16 - total cholesterol (plasma CHOL) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means2.59   mmol/L 2.65   mmol/L
Median of the strain means2.29   mmol/L 2.32   mmol/L
SD of the strain means± 1.28 ± 0.888
Coefficient of variation (CV)0.493 0.335
Min–max range of strain means1.60   –   5.09   mmol/L 1.84   –   4.39   mmol/L
Mean sample size per strain3.5   mice 3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3402 0.3402 0.4049 0.5294
strain 4 47.0491 11.7623 13.9992 < 0.0001
sex:strain 4 2.6639 0.666 0.7926 0.5393
Residuals 30 25.2063 0.8402


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 2.44 0.0419   4 0.0209 0.0172 2.39, 2.48 -0.12
129S1/SvImJ m 3.24 0.13   4 0.0652 0.0402 3.1, 3.41 0.66
A/J f 1.6 0.132   4 0.0662 0.083 1.41, 1.69 -0.78
A/J m 1.84 0.0934   4 0.0467 0.0507 1.74, 1.95 -0.92
C57BL/6J f 1.77 0.149   4 0.0745 0.0842 1.59, 1.93 -0.64
C57BL/6J m 2.32 0.137   4 0.0686 0.0591 2.2, 2.5 -0.38
NOD/ShiLtJ f 2.13 0.555   4 0.277 0.26 1.69, 2.94 -0.36
NOD/ShiLtJ m 2.15 0.153   4 0.0767 0.0714 2.02, 2.3 -0.57
NZO/HlLtJ f 5.09 0.0973   4 0.0486 0.0191 4.94, 5.15 1.96
NZO/HlLtJ m 4.39 2.82   4 1.41 0.643 0.582, 6.62 1.95
PWK/PhJ m 2.07 0.0   1   0.0 0.0 2.07, 2.07 -0.66
WSB/EiJ f 2.51 0.0   1   0.0 0.0 2.51, 2.51 -0.06
WSB/EiJ m 2.57 0.226   3 0.13 0.0881 2.36, 2.81 -0.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 2.4365 0.4583 3.3725 1.5005
129S1/SvImJ m 3.244 0.4583 4.18 2.308
A/J f 1.5963 0.4583 2.5323 0.6602
A/J m 1.8418 0.4583 2.7778 0.9057
C57BL/6J f 1.7683 0.4583 2.7043 0.8322
C57BL/6J m 2.319 0.4583 3.255 1.383
NOD/ShiLtJ f 2.1333 0.4583 3.0693 1.1972
NOD/ShiLtJ m 2.149 0.4583 3.085 1.213
NZO/HlLtJ f 5.0873 0.4583 6.0233 4.1512
NZO/HlLtJ m 4.39 0.4583 5.326 3.454


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 2.8403 0.3241 3.5021 2.1784
A/J both 1.719 0.3241 2.3809 1.0571
C57BL/6J both 2.0436 0.3241 2.7055 1.3818
NOD/ShiLtJ both 2.1411 0.3241 2.803 1.4793
NZO/HlLtJ both 4.7386 0.3241 5.4005 4.0768




  GWAS USING LINEAR MIXED MODELS