MPD: Project measures / variables set: GMC16 LDH

Project measures / variables set: GMC16 LDH

ID, description, units	MPD:56532 LDH lactic acid dehydrogenase (plasma LDH) [IU/L]
Measures	• age 16-17wks • 20-21wks
Data set, strains	GMC16 inbred w/CC8 8 strains sex: both
Procedure	metabolic panel
Comparison	multiple cohorts measured at two age timepoints
Ontology mappings	VT:0001570 blood enzyme amount MA:0002501 plasma MP:0002943 abnormal lactate dehydrogenase level

Values Means Δ Means Z-scores

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GMC16 - lactic acid dehydrogenase (plasma LDH)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
age	1	189.3422	189.3422	0.02	0.8879
sex	1	3240.671	3240.671	0.3416	0.5601
strain	4	134736.408	33684.102	3.5508	0.0091
age:sex	1	20731.5741	20731.5741	2.1854	0.1421
age:strain	4	85771.3957	21442.8489	2.2604	0.0669
sex:strain	4	27295.846	6823.9615	0.7194	0.5804
age:sex:strain	4	164740.8374	41185.2094	4.3416	0.0026
Residuals	114	1081432.5949	9486.2508

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
GMC16	56532	metabolic panel	(none)	lactic acid dehydrogenase (plasma LDH) [IU/L] at age 16-17wks LDH_17	inbred w/CC8	7	both	16-17wks
GMC16	56533	metabolic panel	(none)	lactic acid dehydrogenase (plasma LDH) [IU/L] at age 20-21wks LDH_21	inbred w/CC8	8	both	20-21wks