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Project measure / variable:   GMC16   LDH_17

ID, description, units MPD:56532   LDH_17   lactic acid dehydrogenase (plasma LDH)   [IU/L]  at age 16-17wks  
Data set, strains GMC16   inbred w/CC8   7 strains     sex: both     age: 16-17wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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GMC16 - lactic acid dehydrogenase (plasma LDH) at age 16-17wks



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains7 strains
Mean of the strain means286   IU/L 306   IU/L
Median of the strain means270   IU/L 259   IU/L
SD of the strain means± 73.8 ± 91.3
Coefficient of variation (CV)0.258 0.298
Min–max range of strain means215   –   410   IU/L 241   –   491   IU/L
Mean sample size per strain3.5   mice 3.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 23444.964 23444.964 2.3393 0.1366
strain 4 66687.7465 16671.9366 1.6635 0.1845
sex:strain 4 140682.9835 35170.7459 3.5092 0.0183
Residuals 30 300669.83 10022.3277


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 263.0 88.8   4 44.4 0.338 182.0, 351.0 -0.31
129S1/SvImJ m 251.0 101.0   4 50.5 0.403 155.0, 392.0 -0.6
A/J f 220.0 19.6   4 9.82 0.0894 200.0, 237.0 -0.89
A/J m 244.0 56.6   4 28.3 0.232 177.0, 316.0 -0.68
C57BL/6J f 277.0 68.0   4 34.0 0.246 206.0, 340.0 -0.12
C57BL/6J m 301.0 13.7   4 6.87 0.0456 282.0, 312.0 -0.06
NOD/ShiLtJ f 329.0 73.5   4 36.8 0.224 246.0, 425.0 0.59
NOD/ShiLtJ m 259.0 25.9   4 12.9 0.0998 234.0, 295.0 -0.52
NZO/HlLtJ f 215.0 56.4   4 28.2 0.262 176.0, 296.0 -0.96
NZO/HlLtJ m 491.0 254.0   4 127.0 0.517 274.0, 855.0 2.02
PWK/PhJ m 241.0 0.0   1   0.0 0.0 241.0, 241.0 -0.71
WSB/EiJ f 410.0 0.0   1   0.0 0.0 410.0, 410.0 1.68
WSB/EiJ m 356.0 78.7   3 45.5 0.221 284.0, 440.0 0.55


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 263.1 50.0558 365.3276 160.8724
129S1/SvImJ m 250.8 50.0558 353.0276 148.5724
A/J f 219.65 50.0558 321.8776 117.4224
A/J m 244.225 50.0558 346.4526 141.9974
C57BL/6J f 276.825 50.0558 379.0526 174.5974
C57BL/6J m 301.075 50.0558 403.3026 198.8474
NOD/ShiLtJ f 328.875 50.0558 431.1026 226.6474
NOD/ShiLtJ m 259.05 50.0558 361.2776 156.8224
NZO/HlLtJ f 215.4 50.0558 317.6276 113.1724
NZO/HlLtJ m 490.8 50.0558 593.0276 388.5724


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 256.95 35.3948 329.2358 184.6642
A/J both 231.9375 35.3948 304.2233 159.6517
C57BL/6J both 288.95 35.3948 361.2358 216.6642
NOD/ShiLtJ both 293.9625 35.3948 366.2483 221.6767
NZO/HlLtJ both 353.1 35.3948 425.3858 280.8142




  GWAS USING LINEAR MIXED MODELS