MPD: Project measures / variables set: Gould2 FC_immediate

Project measures / variables set: Gould2 FC_immediate_acu

ID, description, units	MPD:47131 FC_immediate_acu acute group, percent immobility in training chamber after first stimulus pairing [%] nicotine study
Measures	• dose (mg): • control • 0.045 • 0.09 • 0.18
Data set, strains	Gould2 inbred 8 strains sex: m age: 8-12wks
Procedure	fear conditioning test
Comparison	control group vs. multiple treatment / dosage groups
Ontology mappings	VT:0010527 associative learning trait VT:0010715 fear-related behavior trait VT:0010721 response to nicotine trait MP:0002062 abnormal associative learning MP:0003106 abnormal fear-related response MP:0020160 abnormal behavioral response to nicotine

Values Means Δ Means Z-scores

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Gould2 - acute group, percent immobility in training chamber after first stimulus pairing

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
dose	3	85.758	28.586	0.3569	0.7842
strain	7	70013.7902	10001.97	124.8623	< 0.0001
dose:strain	21	1184.5848	56.4088	0.7042	0.8289
Residuals	326	26113.8971	80.104

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Gould2	47131	fear conditioning test	nicotine	acute group, percent immobility in training chamber after first stimulus pairing [%] dose control mg FC_immediate_acu_0	inbred	8	m
Gould2	47132	fear conditioning test	nicotine	acute group, percent immobility in training chamber after first stimulus pairing [%] dose 0.045 mg FC_immediate_acu_045	inbred	8	m
Gould2	47133	fear conditioning test	nicotine	acute group, percent immobility in training chamber after first stimulus pairing [%] dose 0.09 mg FC_immediate_acu_09	inbred	8	m
Gould2	47134	fear conditioning test	nicotine	acute group, percent immobility in training chamber after first stimulus pairing [%] dose 0.18 mg FC_immediate_acu_18	inbred	8	m