MPD: Project measures / variables set: Crabbe3 ARR1

Project measures / variables set: Crabbe3 ARR1_30rpm

ID, description, units	MPD:15845 ARR1_30rpm latency to-fall, accelerating rotarod, test day 2 30 rpm/min (ARR1) [s] ethanol study
Measures	• baseline • ethanol • difference
Data set, strains	Crabbe3 inbred 8 strains sex: both age: 9-17wks
Procedure	rotarod
Comparison	repeated measures, baseline then treated, same cohort
Ontology mappings	VT:0001516 motor coordination/balance trait VT:0010489 response to alcohol trait MP:0001516 abnormal motor coordination/balance MP:0020157 abnormal behavioral response to alcohol

Values Means Δ Means Z-scores

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Crabbe3 - latency to-fall, accelerating rotarod, test day 2 30 rpm/min (ARR1)

ANOVA Summary "within" = Within error "between" = Between Error (Animal ID)

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
between sex	1	26.6983	26.6983	0.1651	0.6861
between strain	7	9050.7318	1292.9617	7.9954	< 0.0001
between sex:strain	7	1294.7812	184.9687	1.1438	0.3497
between Residuals	56	9055.9753	161.7138
within group	1	314.1756	314.1756	2.0459	0.1582
within group:sex	1	374.0933	374.0933	2.4361	0.1242
within group:strain	7	2924.9068	417.8438	2.721	0.0168
within group:sex:strain	7	377.4527	53.9218	0.3511	0.9263
within Residuals	56	8599.4367	153.5614

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Crabbe3	15845	rotarod	ethanol	latency to-fall, accelerating rotarod, test day 2 30 rpm/min (ARR1) [s] baseline ARR1_pre_30rpm	inbred	8	both	9-17wks
Crabbe3	15846	rotarod	ethanol	latency to-fall, accelerating rotarod, test day 2 30 rpm/min (ARR1) [s] ethanol ARR1_post_30rpm	inbred	8	both	9-17wks
Crabbe3	15847	rotarod	ethanol	latency to-fall, accelerating rotarod, test day 2 30 rpm/min (ARR1) [s] difference ARR1_chg_30rpm	inbred	8	both	9-17wks	(supplemental / summary measure)