MPD: Project measure / variable: Petkova1 LYM

Dimensions Width: px Height: px

Download Plot

Visualization Options Least squares means Alphabetical order Strains on X-axis Individual points

Petkova1 - lymphocyte differential (LYM; percentage of total WBC) at age 12mo

Measure Summary	Female	Male
Number of strains tested	30 strains	30 strains
Mean of the strain means	62.1 %	58.9 %
Median of the strain means	65.3 %	60.3 %
SD of the strain means	± 14.5	± 11.5
Coefficient of variation (CV)	0.234	0.196
Min–max range of strain means	20.4 – 87.6 %	37.1 – 82.0 %
Mean sample size per strain	7.6 mice	7.7 mice

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p value (Pr>F)
sex	1	802.8237	802.8237	12.3858	0.0005
strain	28	59628.1523	2129.5769	32.8548	< 0.0001
sex:strain	28	16310.2353	582.5084	8.9869	< 0.0001
Residuals	389	25214.1365	64.8178

Q-Q normality assessment based on residuals

STRAIN MEANS (UNADJUSTED)

Strain	Sex	Mean	SD	N mice	SEM	CV	Min, Max	Z score
129S1/SvImJ	f	72.0	4.37	8	1.54	0.0607	65.6, 79.1	0.68
129S1/SvImJ	m	37.1	9.17	8	3.24	0.247	20.9, 50.0	-1.89
A/J	f	65.8	8.23	8	2.91	0.125	53.2, 76.9	0.25
A/J	m	68.4	9.7	8	3.43	0.142	48.2, 77.4	0.82
AKR/J	m	60.1	17.3	5	7.74	0.288	42.4, 88.6	0.1
BALB/cByJ	f	68.3	3.39	8	1.2	0.0497	63.9, 73.5	0.43
BALB/cByJ	m	57.6	6.45	8	2.28	0.112	45.0, 66.5	-0.11
BTBR T⁺ Itpr3^tf/J	f	80.5	1.83	8	0.646	0.0227	77.7, 83.8	1.27
BTBR T⁺ Itpr3^tf/J	m	71.6	6.47	7	2.45	0.0905	58.9, 78.0	1.1
BUB/BnJ	f	72.6	8.32	6	3.4	0.115	59.4, 82.2	0.72
BUB/BnJ	m	74.6	4.56	9	1.52	0.0611	68.4, 80.4	1.36
C3H/HeJ	f	20.4	4.29	8	1.52	0.21	16.0, 29.6	-2.88
C3H/HeJ	m	40.1	6.79	8	2.4	0.169	35.5, 55.0	-1.63
C57BL/10J	f	52.5	8.93	8	3.16	0.17	36.1, 61.1	-0.66
C57BL/10J	m	74.4	5.69	7	2.15	0.0765	63.8, 79.2	1.34
C57BL/6J	f	50.3	10.6	8	3.75	0.211	29.2, 62.0	-0.81
C57BL/6J	m	59.4	4.86	8	1.72	0.0818	54.9, 67.3	0.04
C57BLKS/J	f	70.1	8.83	8	3.12	0.126	54.6, 78.4	0.55
C57BLKS/J	m	68.3	4.23	8	1.49	0.0619	61.9, 73.9	0.81
C57BR/cdJ	f	64.3	6.14	8	2.17	0.0953	56.2, 76.4	0.15
C57BR/cdJ	m	69.0	7.69	8	2.72	0.112	55.4, 81.3	0.87
C57L/J	f	64.9	6.65	7	2.51	0.102	51.5, 70.2	0.19
C57L/J	m	68.0	6.88	8	2.43	0.101	53.0, 76.2	0.79
CAST/EiJ	f	78.3	5.67	3	3.27	0.0725	71.8, 82.4	1.12
CBA/J	f	53.9	20.5	8	7.24	0.38	4.82, 67.4	-0.57
CBA/J	m	51.7	8.84	8	3.13	0.171	37.5, 64.8	-0.63
DBA/2J	f	44.6	9.23	6	3.77	0.207	28.6, 54.0	-1.21
DBA/2J	m	59.5	8.71	7	3.29	0.147	42.6, 66.8	0.05
FVB/NJ	f	74.7	5.14	8	1.82	0.0687	66.6, 81.8	0.87
FVB/NJ	m	57.6	10.2	8	3.61	0.177	40.3, 72.3	-0.11
KK/HlJ	f	46.9	2.93	8	1.04	0.0626	40.0, 49.4	-1.05
KK/HlJ	m	41.4	10.4	8	3.66	0.25	25.7, 54.3	-1.52
LP/J	f	68.5	6.44	7	2.44	0.094	55.5, 75.4	0.44
LP/J	m	63.3	8.55	8	3.02	0.135	51.6, 73.4	0.38
MOLF/EiJ	f	60.9	3.34	7	1.26	0.0548	55.9, 64.8	-0.08
MOLF/EiJ	m	46.2	12.4	9	4.15	0.269	22.4, 62.2	-1.1
MRL/MpJ	f	37.1	7.49	8	2.65	0.202	27.4, 48.4	-1.72
MRL/MpJ	m	41.5	12.2	8	4.32	0.295	21.4, 57.6	-1.51
NON/ShiLtJ	f	41.3	6.14	8	2.17	0.149	28.4, 47.4	-1.44
NON/ShiLtJ	m	49.0	9.39	6	3.83	0.191	37.5, 60.2	-0.86
NZO/HlLtJ	f	61.7	8.17	7	3.09	0.132	46.5, 70.6	-0.03
NZO/HlLtJ	m	61.0	15.4	7	5.8	0.252	33.9, 78.3	0.18
NZW/LacJ	f	80.5	1.82	8	0.643	0.0226	77.0, 83.1	1.27
NZW/LacJ	m	52.9	7.33	8	2.59	0.139	40.7, 61.3	-0.52
P/J	f	70.1	7.31	8	2.59	0.104	59.6, 82.0	0.55
P/J	m	66.4	4.02	7	1.52	0.0606	59.5, 72.7	0.65
PL/J	f	52.8	9.62	7	3.64	0.182	42.4, 71.8	-0.64
PL/J	m	46.4	4.0	6	1.63	0.0862	39.6, 50.6	-1.08
PWD/PhJ	f	59.2	10.9	8	3.85	0.184	35.6, 71.9	-0.2
PWD/PhJ	m	65.6	5.35	8	1.89	0.0816	57.9, 74.9	0.58
RIIIS/J	f	87.6	3.44	8	1.22	0.0392	82.6, 92.1	1.76
RIIIS/J	m	82.0	7.5	8	2.65	0.0915	65.1, 88.6	2.0
SJL/J	f	67.5	8.84	8	3.13	0.131	48.6, 74.9	0.37
SJL/J	m	60.5	6.81	9	2.27	0.113	46.0, 69.2	0.14
SM/J	f	72.4	3.7	8	1.31	0.0511	67.9, 76.9	0.71
SM/J	m	66.6	7.03	8	2.49	0.106	52.5, 74.6	0.67
SWR/J	f	66.8	4.89	7	1.85	0.0732	56.1, 70.8	0.32
SWR/J	m	61.5	6.17	7	2.33	0.1	52.5, 67.5	0.22
WSB/EiJ	f	57.1	8.29	8	2.93	0.145	48.1, 67.8	-0.35
WSB/EiJ	m	45.7	10.4	8	3.67	0.228	30.0, 58.9	-1.15

LEAST SQUARES MEANS (MODEL-ADJUSTED)

Strain	Sex	Mean	SEM	UpperCL	LowerCL
129S1/SvImJ	f	72.025	2.8464	77.6213	66.4287
129S1/SvImJ	m	37.1	2.8464	42.6963	31.5037
A/J	f	65.7875	2.8464	71.3838	60.1912
A/J	m	68.4125	2.8464	74.0088	62.8162
BALB/cByJ	f	68.3125	2.8464	73.9088	62.7162
BALB/cByJ	m	57.625	2.8464	63.2213	52.0287
BTBR T⁺ Itpr3^tf/J	f	80.4625	2.8464	86.0588	74.8662
BTBR T⁺ Itpr3^tf/J	m	71.5571	3.043	77.5399	65.5744
BUB/BnJ	f	72.6167	3.2868	79.0788	66.1546
BUB/BnJ	m	74.6	2.6837	79.8763	69.3237
C3H/HeJ	f	20.4125	2.8464	26.0088	14.8162
C3H/HeJ	m	40.125	2.8464	45.7213	34.5287
C57BL/10J	f	52.4875	2.8464	58.0838	46.8912
C57BL/10J	m	74.4286	3.043	80.4113	68.4458
C57BL/6J	f	50.275	2.8464	55.8713	44.6787
C57BL/6J	m	59.45	2.8464	65.0463	53.8537
C57BLKS/J	f	70.1	2.8464	75.6963	64.5037
C57BLKS/J	m	68.325	2.8464	73.9213	62.7287
C57BR/cdJ	f	64.35	2.8464	69.9463	58.7537
C57BR/cdJ	m	69.0	2.8464	74.5963	63.4037
C57L/J	f	64.9143	3.043	70.897	58.9316
C57L/J	m	67.9875	2.8464	73.5838	62.3912
CBA/J	f	53.89	2.8464	59.4863	48.2937
CBA/J	m	51.6625	2.8464	57.2588	46.0662
DBA/2J	f	44.6	3.2868	51.0621	38.1379
DBA/2J	m	59.4571	3.043	65.4399	53.4744
FVB/NJ	f	74.7125	2.8464	80.3088	69.1162
FVB/NJ	m	57.575	2.8464	63.1713	51.9787
KK/HlJ	f	46.8625	2.8464	52.4588	41.2662
KK/HlJ	m	41.3625	2.8464	46.9588	35.7662
LP/J	f	68.5286	3.043	74.5113	62.5458
LP/J	m	63.325	2.8464	68.9213	57.7287
MOLF/EiJ	f	60.9143	3.043	66.897	54.9316
MOLF/EiJ	m	46.2111	2.6837	51.4874	40.9348
MRL/MpJ	f	37.15	2.8464	42.7463	31.5537
MRL/MpJ	m	41.5	2.8464	47.0963	35.9037
NON/ShiLtJ	f	41.275	2.8464	46.8713	35.6787
NON/ShiLtJ	m	49.0333	3.2868	55.4954	42.5712
NZO/HlLtJ	f	61.7	3.043	67.6827	55.7173
NZO/HlLtJ	m	61.0286	3.043	67.0113	55.0458
NZW/LacJ	f	80.5375	2.8464	86.1338	74.9412
NZW/LacJ	m	52.9	2.8464	58.4963	47.3037
P/J	f	70.1125	2.8464	75.7088	64.5162
P/J	m	66.3714	3.043	72.3542	60.3887
PL/J	f	52.8	3.043	58.7827	46.8173
PL/J	m	46.4333	3.2868	52.8954	39.9712
PWD/PhJ	f	59.1875	2.8464	64.7838	53.5912
PWD/PhJ	m	65.575	2.8464	71.1713	59.9787
RIIIS/J	f	87.575	2.8464	93.1713	81.9787
RIIIS/J	m	81.9625	2.8464	87.5588	76.3662
SJL/J	f	67.4875	2.8464	73.0838	61.8912
SJL/J	m	60.5333	2.6837	65.8096	55.2571
SM/J	f	72.3625	2.8464	77.9588	66.7662
SM/J	m	66.575	2.8464	72.1713	60.9787
SWR/J	f	66.7571	3.043	72.7399	60.7744
SWR/J	m	61.5	3.043	67.4827	55.5173
WSB/EiJ	f	57.1375	2.8464	62.7338	51.5412
WSB/EiJ	m	45.6625	2.8464	51.2588	40.0662

LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED

Strain	Sex	Mean	SEM	UpperCL	LowerCL
129S1/SvImJ	both	54.5625	2.0127	58.5197	50.6053
A/J	both	67.1	2.0127	71.0572	63.1428
BALB/cByJ	both	62.9688	2.0127	66.926	59.0115
BTBR T⁺ Itpr3^tf/J	both	76.0098	2.0834	80.1059	71.9137
BUB/BnJ	both	73.6083	2.1216	77.7796	69.4371
C3H/HeJ	both	30.2688	2.0127	34.226	26.3115
C57BL/10J	both	63.458	2.0834	67.5541	59.3619
C57BL/6J	both	54.8625	2.0127	58.8197	50.9053
C57BLKS/J	both	69.2125	2.0127	73.1697	65.2553
C57BR/cdJ	both	66.675	2.0127	70.6322	62.7178
C57L/J	both	66.4509	2.0834	70.547	62.3548
CBA/J	both	52.7762	2.0127	56.7335	48.819
DBA/2J	both	52.0286	2.2396	56.4317	47.6254
FVB/NJ	both	66.1438	2.0127	70.101	62.1865
KK/HlJ	both	44.1125	2.0127	48.0697	40.1553
LP/J	both	65.9268	2.0834	70.0229	61.8307
MOLF/EiJ	both	53.5627	2.0286	57.5512	49.5742
MRL/MpJ	both	39.325	2.0127	43.2822	35.3678
NON/ShiLtJ	both	45.1542	2.174	49.4284	40.8799
NZO/HlLtJ	both	61.3643	2.1517	65.5947	57.1339
NZW/LacJ	both	66.7187	2.0127	70.676	62.7615
P/J	both	68.242	2.0834	72.3381	64.1459
PL/J	both	49.6167	2.2396	54.0198	45.2135
PWD/PhJ	both	62.3813	2.0127	66.3385	58.424
RIIIS/J	both	84.7687	2.0127	88.726	80.8115
SJL/J	both	64.0104	1.956	67.8561	60.1647
SM/J	both	69.4688	2.0127	73.426	65.5115
SWR/J	both	64.1286	2.1517	68.359	59.8981
WSB/EiJ	both	51.4	2.0127	55.3572	47.4428

INDIVIDUAL ANIMAL VALUES

Click here to view individual animal values

GWAS USING LINEAR MIXED MODELS

ID, description, units	MPD:24207 LYM_M12 lymphocyte differential (LYM; percentage of total WBC) [%] at age 12mo
Data set, strains	Petkova1 inbred 31 strains sex: both age: 52wks
Procedure	immune cell quantification
Ontology mappings	MA:0000059 blood MP:0000717 abnormal lymphocyte cell number VT:0000717 lymphocyte quantity