MPD: Data set: Project1114

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Project1114: Sleep and Circadian Rhythm in Diversity Outbred Mice (2020) [Pending]

Keenan BT, Galante RJ, Lian J, Simecek P, Gatti DM, Zhang L, Lim DC, Svenson KL, Churchill GA, Pack AI. High-throughput sleep phenotyping produces robust and heritable traits in Diversity Outbred mice and their founder strains. Sleep. pii: zsz278. doi: 10.1093/sleep/zsz278. PubMed 32074270 FullText

Project1114 downloads
• Download Project1114 project data set animal data, as uploaded
• Download Project1114 animal data matrix with factor-related expansion applied as necessary
• Download Project1114 strain means, SD, N, etc. one row per strain/sex/measure
• Download Project1114 supplementary file, DO_PACKLAB_PHENOTYPE_DICTIONARY_20220802.xlsx

Ontology terms mapped to Project1114 measures:

MP:0001259 abnormal body weight
MP:0001392 abnormal locomotor behavior
MP:0011396 abnormal sleep behavior
MP:0020467 abnormal circadian behavior
VT:0001259 body mass
VT:0001392 locomotor behavior trait
VT:0001501 sleep behavior trait
VT:0001502 behavioral circadian rhythm trait

Investigators	Allan I Pack University of Pennsylvania School of Medicine, Philadelphia, PA Brendan T Keenan University of Pennsylvania School of Medicine, Philadelphia, PA Daniel M Gatti The Jackson Laboratory, Bar Harbor, ME
Contact	Allan I Pack pack@mail.med.upenn.edu
Funding Provided By	R01 HL111725, R01 GM070683,P01 HL094307
Project type	Phenotype strain survey data set
MPD identifiers	Project1114 MPD:1114
Data changelog	This project has not yet been released.
Formatted citation	Click above to copy-paste the entire citation for this MPD web page.

[No procedure abstracts have been defined yet]

This study describes high-throughput phenotyping strategies for sleep and circadian behavior in mice, including examinations of robustness, reliability, and heritability among Diversity Outbred (DO) mice.

Mice: DO population ♂ age 8-12 wks

Sort/ Pick	Data set	Procedure / Protocol	Treatment	Phenotype Measure / Variable (click to view)	Panel	Sex	Age	Sample Size (Avg)
Project1114:1	Project1114	monitoring system	(none)	total time sleep in 24 h period [min] total_sleep_day24hr 116998 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:8	Project1114	monitoring system	(none)	total time awake in 24 h period [min] total_wake_day24hr 117005 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:15	Project1114	monitoring system	(none)	number of bouts of sleep in 24 h period [n] sleep_bout_day24hr 117012 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:22	Project1114	monitoring system	(none)	number of bouts awake in 24 h period [n] wake_bout_day24hr 117019 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:29	Project1114	monitoring system	(none)	average sleep bout duration in 24 h period [min] avg_s_boutdur_day24hr 117026 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:36	Project1114	monitoring system	(none)	average wake bout duration in 24 h period [min] avg_w_boutdur_day24hr 117033 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:43	Project1114	monitoring system	(none)	standard deviation of total sleep in 24 h period [min] total_sleep_sd_day24hr 117040 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:50	Project1114	monitoring system	(none)	standard deviation of total wake in 24 h period [min] total_wake_sd_day24hr 117047 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:57	Project1114	monitoring system	(none)	standard deviation of number of sleep bouts in 24 h period [n] sleep_bout_sd_day24hr 117054 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:64	Project1114	monitoring system	(none)	standard deviation of number of awake bouts in 24 h period [n] wake_bout_sd_day24hr 117061 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:71	Project1114	monitoring system	(none)	standard deviation of average sleep bout duration in 24 h period [min] avg_s_boutdur_sd_day24hr 117068 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:78	Project1114	monitoring system	(none)	standard deviation of average awake bout duration in 24 h period [min] avg_w_boutdur_sd_day24hr 117075 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:85	Project1114	monitoring system	(none)	total sleep while lights off [min] total_sleep_lightoff 117082 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:92	Project1114	monitoring system	(none)	total time awake while lights off [min] total_wake_lightoff 117089 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:99	Project1114	monitoring system	(none)	number of sleep bouts while lights off [n] sleep_bout_lightoff 117096 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:106	Project1114	monitoring system	(none)	number of bouts awake while lights off [n] wake_bout_lightoff 117103 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:113	Project1114	monitoring system	(none)	average sleep bout duration while lights off [min] avg_s_boutdur_lightoff 117110 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:120	Project1114	monitoring system	(none)	average wake bout duration while lights off [min] avg_w_boutdur_lightoff 117117 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:127	Project1114	monitoring system	(none)	standard deviation of total sleep while lights off [min] total_sleep_sd_lightoff 117124 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

Project1114:134	Project1114	monitoring system	(none)	standard deviation of total wake while lights off [min] total_wake_sd_lightoff 117131 1 2 3 4 5 6 7	DO population	m	8 - 12 wks	N=46

An error occurred on this page.These results could be incomplete or invalid. Staff have been notified.

Project1114: Sleep and Circadian Rhythm in Diversity Outbred Mice (2020) [Pending]

An error occurred on this page.
These results could be incomplete or invalid. Staff have been notified.