MPD: Project measures / variables set: GMC20 IgG1

Project measures / variables set: GMC20 IgG1

ID, description, units	MPD:56906 IgG1 immunoglobulin G1 (plasma IgG1) [µg/mL]
Measures	• age 16-17wks • 20-21wks
Data set, strains	GMC20 inbred w/CC8 8 strains sex: both
Procedure	immunoglobulin quantification
Comparison	multiple cohorts measured at two age timepoints
Ontology mappings	VT:0002144 B cell development trait VT:0008495 blood immunoglobulin G1 amount MA:0002501 plasma MP:0020175 abnormal IgG1 level

Values Means Δ Means Z-scores

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GMC20 - immunoglobulin G1 (plasma IgG1)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
age	1	147572.4562	147572.4562	1.8185	0.1847
sex	1	13009.5286	13009.5286	0.1603	0.6909
strain	2	231761.7824	115880.8912	1.428	0.2512
age:sex	1	319.3799	319.3799	0.0039	0.9503
age:strain	2	149920.7148	74960.3574	0.9237	0.405
sex:strain	2	37590.6557	18795.3279	0.2316	0.7943
age:sex:strain	2	218591.6146	109295.8073	1.3468	0.2711
Residuals	42	3408310.8176	81150.2576

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
GMC20	56906	immunoglobulin quantification	(none)	immunoglobulin G1 (plasma IgG1) [µg/mL] at age 16-17wks IgG1_17	inbred w/CC8	6	both	16-17wks
GMC20	56907	immunoglobulin quantification	(none)	immunoglobulin G1 (plasma IgG1) [µg/mL] at age 20-21wks IgG1_21	inbred w/CC8	8	both	20-21wks