MPD: Project measures / variables set: Harrill1 liver

Project measures / variables set: Harrill1 liver_CHOL

ID, description, units	MPD:39526 liver_CHOL hepatic cholesterol (CHOL) [mg/dL] isoniazid study
Measures	• control • isoniazid
Data set, strains	Harrill1 inbred 34 strains sex: f age: 8-10wks
Procedure	lipid profile
Comparison	control group vs. treated group
Ontology mappings	VT:0000609 liver physiology trait VT:0001547 lipid amount VT:0010487 response to xenobiotic stimulus trait MA:0000358 liver MP:0012776 abnormal liver cholesterol level

Values Means Δ Means Z-scores

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Harrill1 - hepatic cholesterol (CHOL)

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	1281.1199	1281.1199	18.0859	< 0.0001
strain	33	12785.9947	387.4544	5.4698	< 0.0001
group:strain	33	5894.6873	178.6269	2.5217	< 0.0001
Residuals	202	14308.75	70.8354

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Harrill1	39526	lipid profile	isoniazid	hepatic cholesterol (CHOL) [mg/dL] control liver_CHOL_ctrl	inbred	34	f	8-10wks
Harrill1	39527	lipid profile	isoniazid	hepatic cholesterol (CHOL) [mg/dL] isoniazid liver_CHOL_trt	inbred	34	f	8-10wks