Project measures / variables set:   Berndt2   tidal_vol

ID, description, units MPD:35168   tidal_vol   tidal volume   [mL]  
methacholine study
Measures
• saline    • 5 MCh    • 10 MCh    • 20 MCh    • response index
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Comparisonrepeated measures, baseline then treated multiple doses, same cohort
Ontology mappings

  SIDE-BY-SIDE STRAIN CURVES


  OVERLAPPING STRAIN CURVES
Data
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Berndt2 - tidal volume
Created with Highcharts 6.0.7measureChart context menuFemale129S1/SvImJA/JAKR/JBALB/cByJBALB/cJBTBR T+ Itpr3tf/JBUB/BnJC3H/HeJC57BL/10JC57BL/6JC57BLKS/JC57BR/cdJC57L/JCBA/JCE/JDBA/1JDBA/2JFVB/NJI/LnJKK/HlJLP/JNOD/ShiLtJNON/ShiLtJNZW/LacJPL/JRIIIS/JSJL/JSM/JSWR/Jsaline5 MCh10 MCh20 MCh0.10.20.30.40.50.6
mL

Created with Highcharts 6.0.7measureChart context menuMale129S1/SvImJA/JAKR/JBALB/cByJBALB/cJBTBR T+ Itpr3tf/JBUB/BnJC3H/HeJC57BL/10JC57BL/6JC57BLKS/JC57BR/cdJC57L/JCBA/JCE/JDBA/1JDBA/2JFVB/NJI/LnJKK/HlJLP/JNOD/ShiLtJNON/ShiLtJNZW/LacJPL/JRIIIS/JSJL/JSM/JSWR/Jsaline5 MCh10 MCh20 MCh0.10.20.30.40.50.6
mL


  ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary          "within" = Within error     "between" = Between Error (Animal ID)

Factor DF Sum of squares Mean sum of squares F value p-value (Pr>F)
between   sex 1 0.2814 0.2814 83.4471 < 0.0001
between   strain 28 3.7211 0.1329 39.4058 < 0.0001
between   sex:strain 28 0.2447 0.0087 2.5909 < 0.0001
between   Residuals 412 1.3895 0.0034
within   group 3 1.3243 0.4414 333.277 < 0.0001
within   group:sex 3 0.0354 0.0118 8.9147 < 0.0001
within   group:strain 84 1.2483 0.0149 11.2199 < 0.0001
within   group:sex:strain 84 0.1908 0.0023 1.715 0.0001
within   Residuals 1236 1.6371 0.0013

Q-Q normality assessment based on residuals

  


  INDIVIDUAL MEASURES
ProjectIDTreatmentMeasure / Variable Description PanelStrains
tested		SexAge
Berndt2 35168 plethysmography methacholine tidal volume   [mL]   saline  tidal_vol_saline inbred 29 both 9-12wks
Berndt2 35169 plethysmography methacholine tidal volume   [mL]   5 MCh  tidal_vol_mch5 inbred 29 both 9-12wks
Berndt2 35170 plethysmography methacholine tidal volume   [mL]   10 MCh  tidal_vol_mch10 inbred 29 both 9-12wks
Berndt2 35171 plethysmography methacholine tidal volume   [mL]   20 MCh  tidal_vol_mch20 inbred 29 both 9-12wks
Berndt2 35172 plethysmography methacholine tidal volume   [mL]   response index  tidal_vol_slope inbred 29 both 9-12wks (supplemental /
  summary measure)



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