MPD: Project measures / variables set: Gershenfeld1 OFTcenter

Project measures / variables set: Gershenfeld1 OFTcenter

ID, description, units	MPD:16216 OFTcenter average center time, 2 trials [s] imipramine study
Measures	• baseline • imipramine 30mg/kg
Data set, strains	Gershenfeld1 inbred 12 strains sex: m age: 5-10wks
Procedure	open field test
Comparison	control group vs. treated group
Ontology mappings	VT:0010471 exploratory behavior trait VT:0010487 response to xenobiotic stimulus trait VT:0010716 anxiety-related behavior trait MP:0001362 abnormal anxiety-related response MP:0001392 abnormal locomotor behavior MP:0009745 abnormal behavioral response to xenobiotic MP:0013189 abnormal exploration in a new environment

Values Means Δ Means Z-scores

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Gershenfeld1 - average center time, 2 trials

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA Summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p-value (Pr>F)
group	1	165.2494	165.2494	0.0754	0.7842
strain	11	459637.5519	41785.232	19.0713	< 0.0001
group:strain	11	13411.314	1219.2104	0.5565	0.8593
Residuals	99	216909.4651	2191.0047

Q-Q normality assessment based on residuals

INDIVIDUAL MEASURES

Project	ID		Treatment	Measure / Variable Description	Panel	Strains tested	Sex	Age
Gershenfeld1	16216	open field test	imipramine	average center time, 2 trials [s] baseline OFTcenter	inbred	12	m	5-10wks
Gershenfeld1	16217	open field test	imipramine	average center time, 2 trials [s] imipramine 30mg/kg OFTcenter_Rx	inbred	12	m	5-10wks