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Project measure / variable:   Schwartz2   pctEOS_ova72

ID, description, units MPD:9809   pctEOS_ova72   alveolar eosinophils (percentage of total lavage cells), 72h post-challenge   [%]  OVA-sensitized  
ovalbumin study
Data set, strains Schwartz2   inbred   8 strains     sex: m     age: 6-8wks
Procedure bronchoalveolar lavage assessment
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  STRAIN COMPARISON PLOT
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Schwartz2 - alveolar eosinophils (percentage of total lavage cells), 72h post-challenge OVA-sensitized



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested8 strains
Mean of the strain means42.5   %
Median of the strain means36.4   %
SD of the strain means± 18.4
Coefficient of variation (CV)0.434
Min–max range of strain means27.2   –   81.2   %
Mean sample size per strain4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 7 11848.6421 1692.6632 5.8853 0.0002
Residuals 30 8628.2 287.6067


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 53.2 24.4   5 10.9 0.46 18.0, 76.0 0.58
A/J m 42.0 4.32   4 2.16 0.103 38.0, 48.0 -0.03
BALB/cJ m 27.2 11.0   5 4.93 0.406 11.0, 41.0 -0.83
BTBR T+ Itpr3tf/J m 30.0 17.6   5 7.89 0.588 2.0, 46.0 -0.68
C3H/HeJ m 30.8 23.3   5 10.4 0.758 5.0, 58.0 -0.63
C57BL/6J m 81.2 11.1   5 4.97 0.137 64.0, 94.0 2.1
DBA/2J m 28.0 15.0   5 6.72 0.536 10.0, 44.0 -0.79
FVB/NJ m 47.5 17.1   4 8.53 0.359 33.0, 72.0 0.27


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 53.2 7.5843 68.6892 37.7108
A/J m 42.0 8.4795 59.3174 24.6826
BALB/cJ m 27.2 7.5843 42.6892 11.7108
BTBR T+ Itpr3tf/J m 30.0 7.5843 45.4892 14.5108
C3H/HeJ m 30.8 7.5843 46.2892 15.3108
C57BL/6J m 81.2 7.5843 96.6892 65.7108
DBA/2J m 28.0 7.5843 43.4892 12.5108
FVB/NJ m 47.5 8.4795 64.8174 30.1826




  GWAS USING LINEAR MIXED MODELS