Project measure / variable:   Seburn1   VO2_dark

ID, description, units MPD:9210   VO2_dark   oxygen volume, 3 day test   [mL/kg/h]  dark  
Data set, strains Seburn1   inbred   16 strains     sex: both     age: 7-9wks
Procedure monitoring system
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  STRAIN COMPARISON PLOT
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Seburn1 - oxygen volume, 3 day test dark



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested15 strains16 strains
Mean of the strain means5207   mL/kg/h 4607   mL/kg/h
Median of the strain means5162   mL/kg/h 4610   mL/kg/h
SD of the strain means± 911 ± 849
Coefficient of variation (CV)0.175 0.184
Min–max range of strain means3899   –   6706   mL/kg/h 3078   –   6444   mL/kg/h
Mean sample size per strain8.0   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 21092417.5042 21092417.5042 45.0248 < 0.0001
strain 14 168161011.975 12011500.8554 25.6403 < 0.0001
sex:strain 14 11038049.0583 788432.0756 1.683 0.0609
Residuals 210 98377106.625 468462.4125


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 5606.0 693.0   8 245.0 0.124 4492.0, 6629.0 0.44
129S1/SvImJ m 4804.0 284.0   8 101.0 0.0592 4350.0, 5242.0 0.23
A/J f 5377.0 829.0   8 293.0 0.154 3880.0, 6382.0 0.19
A/J m 4974.0 424.0   8 150.0 0.0853 4508.0, 5639.0 0.43
AKR/J f 4386.0 521.0   8 184.0 0.119 3580.0, 5317.0 -0.9
AKR/J m 4093.0 758.0   8 268.0 0.185 3105.0, 5139.0 -0.61
BALB/cJ f 5162.0 491.0   8 174.0 0.0952 4349.0, 5842.0 -0.05
BALB/cJ m 4881.0 443.0   8 157.0 0.0907 4147.0, 5625.0 0.32
BTBR T+ Itpr3tf/J f 4050.0 896.0   8 317.0 0.221 3137.0, 5456.0 -1.27
BTBR T+ Itpr3tf/J m 3977.0 424.0   8 150.0 0.107 3444.0, 4652.0 -0.74
C3H/HeJ f 5564.0 1621.0   8 573.0 0.291 4286.0, 8456.0 0.39
C3H/HeJ m 4722.0 384.0   8 136.0 0.0812 4254.0, 5506.0 0.14
C57BL/6J f 4123.0 362.0   8 128.0 0.0878 3500.0, 4746.0 -1.19
C57BL/6J m 3078.0 262.0   8 92.8 0.0852 2694.0, 3374.0 -1.8
CAST/EiJ f 6706.0 613.0   8 217.0 0.0913 5911.0, 7541.0 1.65
CAST/EiJ m 6444.0 255.0   8 90.2 0.0396 5997.0, 6796.0 2.16
CBA/J f 4780.0 446.0   8 158.0 0.0933 4201.0, 5602.0 -0.47
CBA/J m 3333.0 630.0   8 223.0 0.189 2550.0, 4377.0 -1.5
FVB/NJ f 3899.0 744.0   8 263.0 0.191 3236.0, 5588.0 -1.44
FVB/NJ m 4077.0 364.0   8 129.0 0.0894 3439.0, 4500.0 -0.62
LP/J f 5872.0 848.0   8 300.0 0.144 4070.0, 6684.0 0.73
LP/J m 5071.0 642.0   8 227.0 0.127 4507.0, 6544.0 0.55
NOD/ShiLtJ f 4631.0 1559.0   8 551.0 0.337 3219.0, 8058.0 -0.63
NOD/ShiLtJ m 4353.0 559.0   8 198.0 0.129 3816.0, 5276.0 -0.3
NZB/BlNJ f 5074.0 474.0   8 168.0 0.0934 4232.0, 5698.0 -0.15
NZB/BlNJ m 4271.0 390.0   8 138.0 0.0913 3676.0, 4915.0 -0.4
PL/J f 6690.0 658.0   8 233.0 0.0983 5792.0, 7797.0 1.63
PL/J m 5519.0 543.0   8 192.0 0.0983 4829.0, 6566.0 1.07
SJL/J m 4498.0 270.0   8 95.6 0.0601 4088.0, 4918.0 -0.13
SWR/J f 6192.0 612.0   8 217.0 0.0989 5412.0, 7020.0 1.08
SWR/J m 5620.0 556.0   8 197.0 0.099 4875.0, 6627.0 1.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 5606.125 241.9872 6083.1604 5129.0896
129S1/SvImJ m 4804.25 241.9872 5281.2854 4327.2146
A/J f 5376.875 241.9872 5853.9104 4899.8396
A/J m 4973.875 241.9872 5450.9104 4496.8396
AKR/J f 4385.625 241.9872 4862.6604 3908.5896
AKR/J m 4093.25 241.9872 4570.2854 3616.2146
BALB/cJ f 5161.5 241.9872 5638.5354 4684.4646
BALB/cJ m 4881.375 241.9872 5358.4104 4404.3396
BTBR T+ Itpr3tf/J f 4049.5 241.9872 4526.5354 3572.4646
BTBR T+ Itpr3tf/J m 3976.75 241.9872 4453.7854 3499.7146
C3H/HeJ f 5563.875 241.9872 6040.9104 5086.8396
C3H/HeJ m 4722.25 241.9872 5199.2854 4245.2146
C57BL/6J f 4123.0 241.9872 4600.0354 3645.9646
C57BL/6J m 3078.25 241.9872 3555.2854 2601.2146
CAST/EiJ f 6706.125 241.9872 7183.1604 6229.0896
CAST/EiJ m 6443.75 241.9872 6920.7854 5966.7146
CBA/J f 4779.5 241.9872 5256.5354 4302.4646
CBA/J m 3332.625 241.9872 3809.6604 2855.5896
FVB/NJ f 3898.625 241.9872 4375.6604 3421.5896
FVB/NJ m 4077.25 241.9872 4554.2854 3600.2146
LP/J f 5872.125 241.9872 6349.1604 5395.0896
LP/J m 5070.625 241.9872 5547.6604 4593.5896
NOD/ShiLtJ f 4631.25 241.9872 5108.2854 4154.2146
NOD/ShiLtJ m 4352.625 241.9872 4829.6604 3875.5896
NZB/BlNJ f 5074.125 241.9872 5551.1604 4597.0896
NZB/BlNJ m 4270.625 241.9872 4747.6604 3793.5896
PL/J f 6690.0 241.9872 7167.0354 6212.9646
PL/J m 5519.0 241.9872 5996.0354 5041.9646
SWR/J f 6192.25 241.9872 6669.2854 5715.2146
SWR/J m 5620.375 241.9872 6097.4104 5143.3396


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 5205.1875 171.1108 5542.5024 4867.8726
A/J both 5175.375 171.1108 5512.6899 4838.0601
AKR/J both 4239.4375 171.1108 4576.7524 3902.1226
BALB/cJ both 5021.4375 171.1108 5358.7524 4684.1226
BTBR T+ Itpr3tf/J both 4013.125 171.1108 4350.4399 3675.8101
C3H/HeJ both 5143.0625 171.1108 5480.3774 4805.7476
C57BL/6J both 3600.625 171.1108 3937.9399 3263.3101
CAST/EiJ both 6574.9375 171.1108 6912.2524 6237.6226
CBA/J both 4056.0625 171.1108 4393.3774 3718.7476
FVB/NJ both 3987.9375 171.1108 4325.2524 3650.6226
LP/J both 5471.375 171.1108 5808.6899 5134.0601
NOD/ShiLtJ both 4491.9375 171.1108 4829.2524 4154.6226
NZB/BlNJ both 4672.375 171.1108 5009.6899 4335.0601
PL/J both 6104.5 171.1108 6441.8149 5767.1851
SWR/J both 5906.3125 171.1108 6243.6274 5568.9976




  GWAS USING LINEAR MIXED MODELS