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Project measure / variable:   Seburn1   VO2_light

ID, description, units MPD:9209   VO2_light   oxygen volume, 3 day test   [mL/kg/h]  light  
Data set, strains Seburn1   inbred   16 strains     sex: both     age: 7-9wks
Procedure monitoring system
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  STRAIN COMPARISON PLOT
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Seburn1 - oxygen volume, 3 day test light



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested15 strains16 strains
Mean of the strain means4188   mL/kg/h 3742   mL/kg/h
Median of the strain means4065   mL/kg/h 3687   mL/kg/h
SD of the strain means± 753 ± 769
Coefficient of variation (CV)0.180 0.205
Min–max range of strain means3203   –   5878   mL/kg/h 2625   –   5510   mL/kg/h
Mean sample size per strain8.0   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 12065098.8375 12065098.8375 40.0749 < 0.0001
strain 14 125301940.025 8950138.5732 29.7284 < 0.0001
sex:strain 14 9033388.975 645242.0696 2.1432 0.011
Residuals 210 63223399.625 301063.8077


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 4388.0 520.0   8 184.0 0.118 3674.0, 5276.0 0.27
129S1/SvImJ m 3660.0 417.0   8 147.0 0.114 3277.0, 4486.0 -0.11
A/J f 3759.0 422.0   8 149.0 0.112 3314.0, 4635.0 -0.57
A/J m 3692.0 400.0   8 142.0 0.108 3235.0, 4422.0 -0.07
AKR/J f 4012.0 501.0   8 177.0 0.125 3366.0, 4909.0 -0.23
AKR/J m 3234.0 292.0   8 103.0 0.0902 2870.0, 3766.0 -0.66
BALB/cJ f 4223.0 621.0   8 220.0 0.147 2965.0, 4893.0 0.05
BALB/cJ m 4062.0 453.0   8 160.0 0.112 3364.0, 4659.0 0.42
BTBR T+ Itpr3tf/J f 3283.0 383.0   8 135.0 0.117 2755.0, 3930.0 -1.2
BTBR T+ Itpr3tf/J m 3205.0 231.0   8 81.7 0.0721 2979.0, 3570.0 -0.7
C3H/HeJ f 3664.0 378.0   8 134.0 0.103 3055.0, 4227.0 -0.7
C3H/HeJ m 3682.0 213.0   8 75.4 0.0579 3342.0, 3913.0 -0.08
C57BL/6J f 3518.0 314.0   8 111.0 0.0893 3181.0, 3990.0 -0.89
C57BL/6J m 2764.0 194.0   8 68.6 0.0702 2482.0, 3056.0 -1.27
CAST/EiJ f 5878.0 457.0   8 161.0 0.0777 5139.0, 6494.0 2.25
CAST/EiJ m 5258.0 525.0   8 186.0 0.0999 4458.0, 6257.0 1.97
CBA/J f 4065.0 393.0   8 139.0 0.0966 3582.0, 4543.0 -0.16
CBA/J m 2625.0 344.0   8 122.0 0.131 2045.0, 3082.0 -1.45
FVB/NJ f 3823.0 236.0   8 83.4 0.0617 3529.0, 4210.0 -0.48
FVB/NJ m 3525.0 329.0   8 116.0 0.0933 3032.0, 3920.0 -0.28
LP/J f 4486.0 1323.0   8 468.0 0.295 3078.0, 6750.0 0.4
LP/J m 3813.0 699.0   8 247.0 0.183 2847.0, 4714.0 0.09
NOD/ShiLtJ f 3203.0 658.0   8 233.0 0.205 2535.0, 4653.0 -1.31
NOD/ShiLtJ m 3114.0 264.0   8 93.4 0.0848 2854.0, 3688.0 -0.82
NZB/BlNJ f 4328.0 578.0   8 204.0 0.133 3735.0, 5442.0 0.19
NZB/BlNJ m 3861.0 856.0   8 303.0 0.222 3059.0, 5460.0 0.15
PL/J f 4636.0 595.0   8 210.0 0.128 3524.0, 5537.0 0.6
PL/J m 4080.0 367.0   8 130.0 0.09 3577.0, 4651.0 0.44
SJL/J m 3787.0 355.0   8 125.0 0.0937 3332.0, 4456.0 0.06
SWR/J f 5547.0 724.0   8 256.0 0.131 4538.0, 6793.0 1.81
SWR/J m 5510.0 1026.0   8 363.0 0.186 4006.0, 7369.0 2.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 4387.5 193.9922 4769.9216 4005.0784
129S1/SvImJ m 3660.0 193.9922 4042.4216 3277.5784
A/J f 3759.0 193.9922 4141.4216 3376.5784
A/J m 3691.875 193.9922 4074.2966 3309.4534
AKR/J f 4011.625 193.9922 4394.0466 3629.2034
AKR/J m 3234.125 193.9922 3616.5466 2851.7034
BALB/cJ f 4222.75 193.9922 4605.1716 3840.3284
BALB/cJ m 4061.625 193.9922 4444.0466 3679.2034
BTBR T+ Itpr3tf/J f 3283.125 193.9922 3665.5466 2900.7034
BTBR T+ Itpr3tf/J m 3204.875 193.9922 3587.2966 2822.4534
C3H/HeJ f 3663.875 193.9922 4046.2966 3281.4534
C3H/HeJ m 3682.25 193.9922 4064.6716 3299.8284
C57BL/6J f 3518.125 193.9922 3900.5466 3135.7034
C57BL/6J m 2763.625 193.9922 3146.0466 2381.2034
CAST/EiJ f 5878.0 193.9922 6260.4216 5495.5784
CAST/EiJ m 5258.25 193.9922 5640.6716 4875.8284
CBA/J f 4065.25 193.9922 4447.6716 3682.8284
CBA/J m 2625.25 193.9922 3007.6716 2242.8284
FVB/NJ f 3823.375 193.9922 4205.7966 3440.9534
FVB/NJ m 3524.75 193.9922 3907.1716 3142.3284
LP/J f 4485.5 193.9922 4867.9216 4103.0784
LP/J m 3813.25 193.9922 4195.6716 3430.8284
NOD/ShiLtJ f 3203.125 193.9922 3585.5466 2820.7034
NOD/ShiLtJ m 3114.25 193.9922 3496.6716 2731.8284
NZB/BlNJ f 4328.25 193.9922 4710.6716 3945.8284
NZB/BlNJ m 3861.0 193.9922 4243.4216 3478.5784
PL/J f 4635.625 193.9922 5018.0466 4253.2034
PL/J m 4080.375 193.9922 4462.7966 3697.9534
SWR/J f 5546.625 193.9922 5929.0466 5164.2034
SWR/J m 5509.875 193.9922 5892.2966 5127.4534


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 4023.75 137.1732 4294.1629 3753.3371
A/J both 3725.4375 137.1732 3995.8504 3455.0246
AKR/J both 3622.875 137.1732 3893.2879 3352.4621
BALB/cJ both 4142.1875 137.1732 4412.6004 3871.7746
BTBR T+ Itpr3tf/J both 3244.0 137.1732 3514.4129 2973.5871
C3H/HeJ both 3673.0625 137.1732 3943.4754 3402.6496
C57BL/6J both 3140.875 137.1732 3411.2879 2870.4621
CAST/EiJ both 5568.125 137.1732 5838.5379 5297.7121
CBA/J both 3345.25 137.1732 3615.6629 3074.8371
FVB/NJ both 3674.0625 137.1732 3944.4754 3403.6496
LP/J both 4149.375 137.1732 4419.7879 3878.9621
NOD/ShiLtJ both 3158.6875 137.1732 3429.1004 2888.2746
NZB/BlNJ both 4094.625 137.1732 4365.0379 3824.2121
PL/J both 4358.0 137.1732 4628.4129 4087.5871
SWR/J both 5528.25 137.1732 5798.6629 5257.8371




  GWAS USING LINEAR MIXED MODELS