Project measure / variable:   Willott1   PPI_tot

ID, description, units MPD:9111   PPI_tot   mean prepulse inhibition (PPI), 70dB   [ratio]  all tones  
Data set, strains Willott1   inbred w/CC7   40 strains     sex: both     age: 5-6wks
Procedure acoustic startle test
Ontology mappings

  STRAIN COMPARISON PLOT
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Willott1 - mean prepulse inhibition (PPI), 70dB all tones



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested40 strains40 strains
Mean of the strain means1.89   ratio 1.92   ratio
Median of the strain means1.82   ratio 1.87   ratio
SD of the strain means± 0.477 ± 0.465
Coefficient of variation (CV)0.253 0.242
Min–max range of strain means1.18   –   2.99   ratio 1.26   –   3.33   ratio
Mean sample size per strain10.1   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.2615 0.2615 0.8937 0.3448
strain 39 164.0449 4.2063 14.3763 < 0.0001
sex:strain 39 8.0846 0.2073 0.7085 0.9094
Residuals 725 212.1239 0.2926


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.49 0.814   10 0.257 0.547 0.554, 2.77 -0.83
129S1/SvImJ m 1.48 0.673   10 0.213 0.455 0.714, 2.88 -0.95
A/J f 2.21 0.519   10 0.164 0.235 1.69, 3.02 0.68
A/J m 2.12 0.615   10 0.194 0.29 1.02, 3.04 0.43
AKR/J f 1.33 0.383   10 0.121 0.287 0.993, 2.21 -1.17
AKR/J m 1.26 0.37   10 0.117 0.293 0.727, 2.0 -1.42
BALB/cJ f 1.87 0.508   18 0.12 0.272 1.02, 2.85 -0.04
BALB/cJ m 1.93 0.363   10 0.115 0.188 1.31, 2.62 0.02
BTBR T+ Itpr3tf/J f 1.84 0.665   10 0.21 0.362 0.856, 2.95 -0.1
BTBR T+ Itpr3tf/J m 1.7 0.522   10 0.165 0.306 1.15, 2.82 -0.48
BUB/BnJ f 1.79 0.269   10 0.0852 0.15 1.39, 2.19 -0.2
BUB/BnJ m 1.87 0.634   10 0.2 0.339 1.3, 3.45 -0.11
C3H/HeJ f 2.42 0.478   10 0.151 0.198 1.6, 3.32 1.12
C3H/HeJ m 2.26 0.507   10 0.16 0.224 1.44, 3.16 0.73
C57BL/10J f 1.22 0.298   10 0.0942 0.244 0.968, 2.0 -1.4
C57BL/10J m 1.38 0.191   10 0.0605 0.138 1.13, 1.66 -1.16
C57BL/6J f 1.84 0.316   11 0.0953 0.172 1.29, 2.3 -0.1
C57BL/6J m 1.91 0.576   10 0.182 0.301 0.964, 2.85 -0.03
C57BLKS/J f 1.26 0.286   10 0.0906 0.227 0.878, 1.86 -1.31
C57BLKS/J m 1.61 0.414   10 0.131 0.258 1.03, 2.38 -0.67
C57BR/cdJ f 2.17 0.591   10 0.187 0.273 1.05, 2.91 0.59
C57BR/cdJ m 2.7 0.546   10 0.173 0.202 1.98, 3.58 1.67
C57L/J f 2.99 0.393   10 0.124 0.132 2.32, 3.59 2.31
C57L/J m 3.33 1.01   10 0.32 0.304 2.17, 5.25 3.03
C58/J f 1.32 0.497   10 0.157 0.378 0.693, 2.26 -1.19
C58/J m 1.35 0.476   10 0.151 0.353 0.651, 2.1 -1.23
CAST/EiJ f 2.2 0.503   10 0.159 0.229 1.37, 3.15 0.66
CAST/EiJ m 2.26 0.616   10 0.195 0.272 1.01, 3.28 0.73
CBA/J f 1.58 0.348   9 0.116 0.22 1.19, 2.21 -0.64
CBA/J m 1.82 0.776   10 0.245 0.427 1.12, 3.8 -0.22
CE/J f 1.31 0.282   10 0.089 0.216 0.987, 1.94 -1.21
CE/J m 1.42 0.147   10 0.0466 0.104 1.19, 1.66 -1.08
CZECHII/EiJ f 1.68 0.537   9 0.179 0.319 1.05, 2.5 -0.43
CZECHII/EiJ m 1.61 0.586   11 0.177 0.365 1.13, 3.08 -0.67
DBA/2J f 2.62 0.533   10 0.168 0.204 1.86, 3.56 1.54
DBA/2J m 2.24 0.585   10 0.185 0.261 1.6, 3.4 0.68
FVB/NJ f 1.74 0.474   10 0.15 0.272 1.0, 2.76 -0.31
FVB/NJ m 1.6 0.479   10 0.152 0.3 0.907, 2.46 -0.69
I/LnJ f 2.11 0.542   10 0.171 0.257 1.29, 3.08 0.47
I/LnJ m 2.4 0.659   10 0.208 0.274 1.48, 3.65 1.03
JF1/MsJ f 2.68 1.05   10 0.332 0.391 1.21, 4.64 1.66
JF1/MsJ m 2.47 1.06   10 0.336 0.43 1.03, 3.67 1.18
KK/HlJ f 1.67 0.548   10 0.173 0.328 1.07, 2.92 -0.45
KK/HlJ m 1.81 0.347   10 0.11 0.192 1.32, 2.3 -0.24
LP/J f 1.35 0.652   10 0.206 0.485 0.817, 2.95 -1.13
LP/J m 1.59 0.491   10 0.155 0.309 0.649, 2.04 -0.71
MA/MyJ f 1.72 0.446   10 0.141 0.259 1.23, 2.42 -0.35
MA/MyJ m 1.6 0.327   10 0.104 0.204 1.16, 2.23 -0.69
MOLF/EiJ f 2.54 0.394   10 0.125 0.155 2.04, 3.12 1.37
MOLF/EiJ m 2.58 0.344   10 0.109 0.134 1.78, 2.9 1.41
MSM/MsJ f 2.32 0.615   10 0.194 0.265 1.31, 3.02 0.91
MSM/MsJ m 2.14 0.798   10 0.252 0.373 1.23, 3.75 0.47
NOD/ShiLtJ f 2.47 0.548   10 0.173 0.222 1.69, 3.45 1.22
NOD/ShiLtJ m 2.38 1.07   10 0.34 0.452 0.936, 4.29 0.98
NON/ShiLtJ f 2.33 0.426   11 0.128 0.183 1.69, 3.15 0.93
NON/ShiLtJ m 2.43 0.725   9 0.242 0.299 1.23, 3.56 1.09
NZB/BlNJ f 2.08 0.513   10 0.162 0.247 1.34, 2.79 0.41
NZB/BlNJ m 2.08 0.695   10 0.22 0.335 1.26, 3.72 0.34
NZW/LacJ f 1.44 0.34   10 0.108 0.236 0.783, 2.07 -0.94
NZW/LacJ m 1.47 0.45   10 0.142 0.305 1.06, 2.33 -0.97
PERA/EiJ f 2.22 0.268   10 0.0847 0.121 1.87, 2.69 0.7
PERA/EiJ m 2.16 0.37   10 0.117 0.172 1.61, 2.75 0.51
PL/J f 1.53 0.619   10 0.196 0.404 1.0, 3.08 -0.75
PL/J m 1.36 0.284   10 0.0897 0.209 0.983, 1.93 -1.21
PWK/PhJ f 2.11 0.527   8 0.186 0.249 1.47, 2.85 0.47
PWK/PhJ m 1.98 0.416   10 0.132 0.21 1.1, 2.71 0.13
RIIIS/J f 1.54 0.731   10 0.231 0.475 0.732, 2.99 -0.73
RIIIS/J m 1.39 0.507   10 0.16 0.364 0.886, 2.57 -1.14
SEA/GnJ f 1.8 0.454   14 0.121 0.253 0.902, 2.58 -0.18
SEA/GnJ m 2.0 0.594   10 0.188 0.297 1.15, 2.88 0.17
SJL/J f 2.53 0.533   10 0.168 0.211 1.83, 3.52 1.35
SJL/J m 2.61 0.494   10 0.156 0.189 2.0, 3.67 1.48
SM/J f 1.18 0.176   10 0.0557 0.149 0.994, 1.55 -1.48
SM/J m 1.28 0.283   10 0.0896 0.22 0.704, 1.64 -1.38
SPRET/EiJ f 1.33 0.361   10 0.114 0.271 0.841, 2.14 -1.17
SPRET/EiJ m 1.87 0.583   10 0.184 0.312 1.06, 2.73 -0.11
SWR/J f 1.41 0.333   10 0.105 0.237 1.09, 2.12 -1.0
SWR/J m 1.56 0.336   10 0.106 0.215 1.1, 2.08 -0.78
WSB/EiJ f 2.23 0.48   7 0.181 0.215 1.41, 2.89 0.72
WSB/EiJ m 1.86 0.406   8 0.143 0.218 1.54, 2.55 -0.13


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.4868 0.1711 1.8226 1.151
129S1/SvImJ m 1.4783 0.1711 1.8142 1.1425
A/J f 2.2135 0.1711 2.5493 1.8777
A/J m 2.1227 0.1711 2.4586 1.7869
AKR/J f 1.3325 0.1711 1.6683 0.9967
AKR/J m 1.2625 0.1711 1.5983 0.9267
BALB/cJ f 1.8669 0.1275 2.1172 1.6166
BALB/cJ m 1.9335 0.1711 2.2693 1.5977
BTBR T+ Itpr3tf/J f 1.8366 0.1711 2.1724 1.5008
BTBR T+ Itpr3tf/J m 1.705 0.1711 2.0408 1.3692
BUB/BnJ f 1.793 0.1711 2.1288 1.4572
BUB/BnJ m 1.8679 0.1711 2.2037 1.532
C3H/HeJ f 2.4156 0.1711 2.7514 2.0797
C3H/HeJ m 2.2605 0.1711 2.5963 1.9247
C57BL/10J f 1.2218 0.1711 1.5577 0.886
C57BL/10J m 1.3845 0.1711 1.7203 1.0487
C57BL/6J f 1.84 0.1631 2.1602 1.5198
C57BL/6J m 1.9144 0.1711 2.2502 1.5786
C57BLKS/J f 1.2596 0.1711 1.5954 0.9238
C57BLKS/J m 1.6057 0.1711 1.9416 1.2699
C57BR/cdJ f 2.167 0.1711 2.5028 1.8312
C57BR/cdJ m 2.698 0.1711 3.0338 2.3622
C57L/J f 2.986 0.1711 3.3218 2.6502
C57L/J m 3.327 0.1711 3.6628 2.9912
C58/J f 1.3163 0.1711 1.6521 0.9804
C58/J m 1.3479 0.1711 1.6837 1.0121
CAST/EiJ f 2.2 0.1711 2.5358 1.8642
CAST/EiJ m 2.2642 0.1711 2.6 1.9284
CBA/J f 1.5846 0.1803 1.9386 1.2306
CBA/J m 1.8154 0.1711 2.1513 1.4796
CE/J f 1.3062 0.1711 1.642 0.9704
CE/J m 1.4245 0.1711 1.7603 1.0887
CZECHII/EiJ f 1.6819 0.1803 2.0359 1.3279
CZECHII/EiJ m 1.6061 0.1631 1.9263 1.2859
DBA/2J f 2.616 0.1711 2.9518 2.2802
DBA/2J m 2.2419 0.1711 2.5777 1.9061
FVB/NJ f 1.7428 0.1711 2.0786 1.407
FVB/NJ m 1.5994 0.1711 1.9353 1.2636
I/LnJ f 2.1125 0.1711 2.4483 1.7767
I/LnJ m 2.403 0.1711 2.7388 2.0672
JF1/MsJ f 2.6832 0.1711 3.019 2.3473
JF1/MsJ m 2.473 0.1711 2.8088 2.1372
KK/HlJ f 1.6707 0.1711 2.0065 1.3349
KK/HlJ m 1.8085 0.1711 2.1443 1.4727
LP/J f 1.3459 0.1711 1.6817 1.01
LP/J m 1.5895 0.1711 1.9253 1.2537
MA/MyJ f 1.721 0.1711 2.0568 1.3852
MA/MyJ m 1.602 0.1711 1.9378 1.2662
MOLF/EiJ f 2.5405 0.1711 2.8763 2.2047
MOLF/EiJ m 2.5755 0.1711 2.9113 2.2397
MSM/MsJ f 2.325 0.1711 2.6608 1.9892
MSM/MsJ m 2.1366 0.1711 2.4724 1.8008
NOD/ShiLtJ f 2.4665 0.1711 2.8023 2.1307
NOD/ShiLtJ m 2.3751 0.1711 2.7109 2.0393
NON/ShiLtJ f 2.3291 0.1631 2.6493 2.0089
NON/ShiLtJ m 2.4282 0.1803 2.7822 2.0742
NZB/BlNJ f 2.079 0.1711 2.4148 1.7432
NZB/BlNJ m 2.076 0.1711 2.4118 1.7402
NZW/LacJ f 1.4412 0.1711 1.7771 1.1054
NZW/LacJ m 1.4737 0.1711 1.8095 1.1379
PERA/EiJ f 2.2205 0.1711 2.5563 1.8847
PERA/EiJ m 2.156 0.1711 2.4918 1.8202
PL/J f 1.5322 0.1711 1.868 1.1964
PL/J m 1.3575 0.1711 1.6934 1.0217
PWK/PhJ f 2.1131 0.1912 2.4886 1.7377
PWK/PhJ m 1.9768 0.1711 2.3127 1.641
RIIIS/J f 1.5389 0.1711 1.8747 1.203
RIIIS/J m 1.3919 0.1711 1.7278 1.0561
SEA/GnJ f 1.7976 0.1446 2.0815 1.5138
SEA/GnJ m 1.9979 0.1711 2.3337 1.6621
SJL/J f 2.527 0.1711 2.8628 2.1912
SJL/J m 2.607 0.1711 2.9428 2.2712
SM/J f 1.1779 0.1711 1.5137 0.842
SM/J m 1.285 0.1711 1.6208 0.9492
SPRET/EiJ f 1.3337 0.1711 1.6695 0.9979
SPRET/EiJ m 1.8671 0.1711 2.2029 1.5313
SWR/J f 1.4077 0.1711 1.7436 1.0719
SWR/J m 1.5642 0.1711 1.9001 1.2284
WSB/EiJ f 2.2329 0.2044 2.6342 1.8315
WSB/EiJ m 1.8631 0.1912 2.2386 1.4877


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.4826 0.121 1.72 1.2451
A/J both 2.1681 0.121 2.4056 1.9307
AKR/J both 1.2975 0.121 1.535 1.06
BALB/cJ both 1.9002 0.1067 2.1096 1.6908
BTBR T+ Itpr3tf/J both 1.7708 0.121 2.0083 1.5333
BUB/BnJ both 1.8304 0.121 2.0679 1.593
C3H/HeJ both 2.338 0.121 2.5755 2.1006
C57BL/10J both 1.3032 0.121 1.5406 1.0657
C57BL/6J both 1.8772 0.1182 2.1092 1.6452
C57BLKS/J both 1.4327 0.121 1.6701 1.1952
C57BR/cdJ both 2.4325 0.121 2.67 2.195
C57L/J both 3.1565 0.121 3.394 2.919
C58/J both 1.3321 0.121 1.5695 1.0946
CAST/EiJ both 2.2321 0.121 2.4696 1.9946
CBA/J both 1.7 0.1243 1.944 1.4561
CE/J both 1.3653 0.121 1.6028 1.1279
CZECHII/EiJ both 1.644 0.1216 1.8826 1.4053
DBA/2J both 2.4289 0.121 2.6664 2.1915
FVB/NJ both 1.6711 0.121 1.9086 1.4337
I/LnJ both 2.2577 0.121 2.4952 2.0203
JF1/MsJ both 2.5781 0.121 2.8155 2.3406
KK/HlJ both 1.7396 0.121 1.9771 1.5021
LP/J both 1.4677 0.121 1.7051 1.2302
MA/MyJ both 1.6615 0.121 1.899 1.424
MOLF/EiJ both 2.558 0.121 2.7955 2.3205
MSM/MsJ both 2.2308 0.121 2.4683 1.9933
NOD/ShiLtJ both 2.4208 0.121 2.6583 2.1833
NON/ShiLtJ both 2.3787 0.1216 2.6173 2.14
NZB/BlNJ both 2.0775 0.121 2.315 1.84
NZW/LacJ both 1.4575 0.121 1.6949 1.22
PERA/EiJ both 2.1883 0.121 2.4257 1.9508
PL/J both 1.4449 0.121 1.6823 1.2074
PWK/PhJ both 2.045 0.1283 2.2968 1.7931
RIIIS/J both 1.4654 0.121 1.7029 1.2279
SEA/GnJ both 1.8978 0.112 2.1176 1.6779
SJL/J both 2.567 0.121 2.8045 2.3295
SM/J both 1.2314 0.121 1.4689 0.994
SPRET/EiJ both 1.6004 0.121 1.8379 1.3629
SWR/J both 1.486 0.121 1.7235 1.2485
WSB/EiJ both 2.048 0.14 2.3228 1.7732




  GWAS USING LINEAR MIXED MODELS