Project measure / variable:   CSNA03   dist_f30_cocaine_in_d1

ID, description, units MPD:90331   dist_f30_cocaine_in_d1   distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders   [cm]  day 1  
cocaine study
Data set, strains CSNA03   inbred w/CC8   10 strains     sex: both     age: 8-14wks
Procedure open field test
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  STRAIN COMPARISON PLOT
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CSNA03 - distance traveled, first 30 min (pre-injection), on successive days, cocaine group, founders day 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means7904.0   cm 6120.0   cm
Median of the strain means6438.0   cm 5700.0   cm
SD of the strain means± 6039.0 ± 3684.0
Coefficient of variation (CV)0.764 0.6019
Min–max range of strain means686.9   –   20515.0   cm 1656.0   –   12929.0   cm
Mean sample size per strain6.2   mice 6.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 104648113.7358 104648113.7358 4.2486 0.0417
strain 8 2630448745.2828 328806093.1603 13.3491 < 0.0001
sex:strain 8 424113041.114 53014130.1392 2.1523 0.037
Residuals 106 2610918263.1078 24631304.3689


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 686.9 839.5   6 342.7 1.2222 -1.2
129S1/SvImJ m 1656.0 1479.0   6 603.8 0.893 60.2, 3668.0 -1.21
A/J f 2701.0 1600.0   12 461.9 0.5924 650.8, 5912.0 -0.86
A/J m 2654.0 1235.0   12 356.7 0.4655 89.89, 5309.0 -0.94
C57BL/6J f 6994.0 1821.0   6 743.4 0.2604 4631.0, 9288.0 -0.15
C57BL/6J m 5876.0 476.9   7 180.2 0.0812 5097.0, 6595.0 -0.07
C57BL/6NJ f 5881.0 0.0   1   0.0 0.0 5881.0, 5881.0 -0.34
C57BL/6NJ m 3615.0 0.0   1   0.0 0.0 3615.0, 3615.0 -0.68
CAST/EiJ f 12700.0 3073.0   6 1254.0 0.2419 7818.0, 16082.0 0.79
CAST/EiJ m 8890.0 3028.0   5 1354.0 0.3406 6472.0, 13888.0 0.75
DBA/2J f 5623.0 714.9   3 412.7 0.1271 4801.0, 6097.0 -0.38
DBA/2J m 5523.0 2430.0   4 1215.0 0.44 2627.0, 8160.0 -0.16
NOD/ShiLtJ f 12946.0 2056.0   6 839.4 0.1588 10643.0, 16666.0 0.83
NOD/ShiLtJ m 12929.0 3228.0   6 1318.0 0.2497 9297.0, 18263.0 1.85
NZO/HlLtJ f 2340.0 755.2   6 308.3 0.3228 1085.0, 3246.0 -0.92
NZO/HlLtJ m 2330.0 792.5   7 299.5 0.3402 1463.0, 3581.0 -1.03
PWK/PhJ f 8658.0 2693.0   9 897.8 0.3111 4656.0, 13252.0 0.12
PWK/PhJ m 8729.0 2300.0   9 766.7 0.2635 5124.0, 12186.0 0.71
WSB/EiJ f 20515.0 18849.0   7 7124.0 0.9188 9170.0, 62695.0 2.09
WSB/EiJ m 9003.0 4455.0   7 1684.0 0.4948 5349.0, 18736.0 0.78


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 686.8616666667 2026.1336073477 4703.8686085652 -3330.1452752319
129S1/SvImJ m 1656.25 2026.1336073477 5673.2569418985 -2360.7569418985
A/J f 2701.0916666667 1432.6928133455 5541.5445153566 -139.3611820232
A/J m 2654.3241666667 1432.6928133455 5494.7770153566 -186.1286820232
C57BL/6J f 6993.8333333333 2026.1336073477 11010.8402752319 2976.8263914348
C57BL/6J m 5876.1428571429 1875.8352185071 9595.1686248784 2157.1170894073
CAST/EiJ f 12700.0 2026.1336073477 16717.0069418986 8682.9930581015
CAST/EiJ m 8890.4 2219.5181625273 13290.8106314654 4489.9893685347
DBA/2J f 5623.3333333333 2865.385626691 11304.2390307131 -57.5723640464
DBA/2J m 5523.25 2481.4967443532 10443.0586504346 603.4413495654
NOD/ShiLtJ f 12946.5 2026.1336073477 16963.5069418985 8929.4930581015
NOD/ShiLtJ m 12929.0 2026.1336073477 16946.0069418985 8911.9930581015
NZO/HlLtJ f 2339.8333333333 2026.1336073477 6356.8402752319 -1677.1736085652
NZO/HlLtJ m 2329.7142857143 1875.8352185071 6048.7400534498 -1389.3114820212
PWK/PhJ f 8657.8888888889 1654.3311629021 11937.761322512 5378.0164552658
PWK/PhJ m 8729.3333333333 1654.3311629021 12009.2057669564 5449.4608997102
WSB/EiJ f 20514.5714285714 1875.8352185071 24233.597196307 16795.5456608359
WSB/EiJ m 9003.4285714286 1875.8352185071 12722.4543391641 5284.402803693


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1171.5558333333 1432.6928133455 4012.0086820232 -1668.8970153566
A/J both 2677.7079166667 1013.0668036738 4686.2113876159 669.2044457174
C57BL/6J both 6434.9880952381 1380.5773395409 9172.1169482674 3697.8592422088
CAST/EiJ both 10795.2 1502.6208993465 13774.2920805161 7816.1079194839
DBA/2J both 5573.2916666667 1895.2744446308 9330.8575908859 1815.7257424475
NOD/ShiLtJ both 12937.75 1432.6928133455 15778.2028486899 10097.2971513101
NZO/HlLtJ both 2334.7738095238 1380.5773395409 5071.9026625531 -402.3550435055
PWK/PhJ both 8693.6111111111 1169.7887836163 11012.8311503528 6374.3910718694
WSB/EiJ both 14759.0 1326.4158033949 17388.7483397733 12129.2516602267




  GWAS USING LINEAR MIXED MODELS