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Project measure / variable:   Neuner1   cfc_6mo_shock4

ID, description, units MPD:65966   cfc_6mo_shock4   percentage of time spent freezing during 40 s interval post shock at 6 mo of age, day 1 contextual fear conditioning   [%]  4th shock  
Data set, strains Neuner1   F1 AD-BXD   50 strains     sex: both     age: 23-25wks
Procedure fear conditioning test
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  STRAIN COMPARISON PLOT
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Neuner1 - percentage of time spent freezing during 40 s interval post shock at 6 mo of age, day 1 contextual fear conditioning 4th shock



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested50 strains27 strains
Mean of the strain means40.191   % 36.888   %
Median of the strain means42.084   % 42.078   %
SD of the strain means± 15.627 ± 16.466
Coefficient of variation (CV)0.3888 0.4464
Min–max range of strain means10.0   –   77.33   % 5.665   –   58.85   %
Mean sample size per strain3.7   mice 2.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 266.2028 266.2028 0.6871 0.4092
strain 13 11352.7629 873.2895 2.2542 0.0126
sex:strain 13 3692.7796 284.06 0.7332 0.7264
Residuals 95 36804.1677 387.4123


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
(B6.5XFAD x B6)F1-ADtg f 46.875 21.984   2   15.545 0.469 31.33, 62.42 0.43
(B6.5XFAD x B6)F1-ADtg m 43.719 10.136   7 3.8311 0.2318 26.0, 54.67 0.41
(B6.5XFAD x B6)F1-Ntg f 44.945 17.887   6 7.3023 0.398 23.33, 75.33 0.3
(B6.5XFAD x B6)F1-Ntg m 46.832 18.536   4 9.2678 0.3958 19.33, 59.33 0.6
(B6.5XFAD x BXD100)F1-ADtg f 33.0 6.4503   4 3.2251 0.1955 24.67, 40.0 -0.46
(B6.5XFAD x BXD100)F1-ADtg m 17.335 15.083   2   10.665 0.8701 6.67, 28.0 -1.19
(B6.5XFAD x BXD100)F1-Ntg f 28.67 5.6569   2   4.0 0.1973 24.67, 32.67 -0.74
(B6.5XFAD x BXD14)F1-ADtg f 28.408 24.101   5 10.778 0.8484 -0.75
(B6.5XFAD x BXD14)F1-Ntg f 73.66 0.47376   2   0.335 0.0064 73.33, 74.0 2.14
(B6.5XFAD x BXD16)F1-ADtg f 18.668 18.191   4 9.0953 0.9744 -1.38
(B6.5XFAD x BXD22)F1-ADtg f 31.603 10.933   3 6.3119 0.3459 20.81, 42.67 -0.55
(B6.5XFAD x BXD22)F1-Ntg f 75.84 0.0   1   0.0 0.0 75.84, 75.84 2.28
(B6.5XFAD x BXD2)F1-ADtg f 34.875 12.305   4 6.1523 0.3528 23.33, 48.0 -0.34
(B6.5XFAD x BXD2)F1-Ntg f 34.994 7.0986   5 3.1746 0.2029 28.0, 44.3 -0.33
(B6.5XFAD x BXD32)F1-ADtg f 34.168 27.514   4 13.757 0.8053 6.0, 60.67 -0.39
(B6.5XFAD x BXD32)F1-ADtg m 18.33 9.8995   2   7.0 0.5401 11.33, 25.33 -1.13
(B6.5XFAD x BXD32)F1-Ntg f 10.0 0.0   1   0.0 0.0 10.0, 10.0 -1.93
(B6.5XFAD x BXD32)F1-Ntg m 44.335 11.787   2   8.335 0.2659 36.0, 52.67 0.45
(B6.5XFAD x BXD34)F1-ADtg f 41.944 20.164   9 6.7213 0.4807 18.0, 78.0 0.11
(B6.5XFAD x BXD34)F1-Ntg f 55.88 21.706   11 6.5446 0.3885 25.5, 86.67 1.0
(B6.5XFAD x BXD42)F1-ADtg f 21.385 20.282   6 8.2803 0.9484 -1.2
(B6.5XFAD x BXD42)F1-Ntg f 16.068 15.305   4 7.6525 0.9525 -1.54
(B6.5XFAD x BXD44)F1-ADtg f 65.0 3.2951   2   2.33 0.0507 62.67, 67.33 1.59
(B6.5XFAD x BXD44)F1-ADtg m 39.93 3.3234   2   2.35 0.0832 37.58, 42.28 0.18
(B6.5XFAD x BXD44)F1-Ntg f 56.66 12.254   2   8.665 0.2163 48.0, 65.33 1.05
(B6.5XFAD x BXD44)F1-Ntg m 14.0 0.0   1   0.0 0.0 14.0, 14.0 -1.39
(B6.5XFAD x BXD51)F1-ADtg f 44.297 10.888   3 6.2862 0.2458 33.56, 55.33 0.26
(B6.5XFAD x BXD51)F1-Ntg f 56.67 16.166   3 9.3333 0.2853 42.0, 74.0 1.05
(B6.5XFAD x BXD55)F1-ADtg f 16.0 16.0   3 9.2376 1.0 -1.55
(B6.5XFAD x BXD55)F1-Ntg f 31.332 9.155   4 4.5775 0.2922 20.0, 41.33 -0.57
(B6.5XFAD x BXD56)F1-ADtg f 48.995 6.6397   2   4.695 0.1355 44.3, 53.69 0.56
(B6.5XFAD x BXD56)F1-Ntg f 46.493 31.111   3 17.962 0.6691 21.48, 81.33 0.4
(B6.5XFAD x BXD60)F1-ADtg f 50.52 5.4377   2   3.845 0.1076 46.67, 54.36 0.66
(B6.5XFAD x BXD60)F1-ADtg m 34.71 29.161   2   20.62 0.8401 14.09, 55.33 -0.13
(B6.5XFAD x BXD60)F1-Ntg f 36.015 46.181   2   32.655 1.2823 3.36, 68.67 -0.27
(B6.5XFAD x BXD61)F1-ADtg f 28.67 16.971   2   12.0 0.5919 16.67, 40.67 -0.74
(B6.5XFAD x BXD61)F1-ADtg m 58.85 5.4023   2   3.82 0.0918 55.03, 62.67 1.33
(B6.5XFAD x BXD61)F1-Ntg f 58.67 0.0   1   0.0 0.0 58.67, 58.67 1.18
(B6.5XFAD x BXD61)F1-Ntg m 43.8 5.9397   2   4.2 0.1356 39.6, 48.0 0.42
(B6.5XFAD x BXD62)F1-ADtg f 24.0 0.0   1   0.0 0.0 24.0, 24.0 -1.04
(B6.5XFAD x BXD62)F1-ADtg m 55.0 0.46669   2   0.33 0.0085 54.67, 55.33 1.1
(B6.5XFAD x BXD62)F1-Ntg f 50.66 17.911   2   12.665 0.3535 38.0, 63.33 0.67
(B6.5XFAD x BXD62)F1-Ntg m 20.0 0.0   1   0.0 0.0 20.0, 20.0 -1.03
(B6.5XFAD x BXD65)F1-ADtg f 42.223 25.036   3 14.455 0.5929 18.0, 68.0 0.13
(B6.5XFAD x BXD65)F1-ADtg m 47.67 18.385   2   13.0 0.3857 34.67, 60.67 0.65
(B6.5XFAD x BXD65)F1-Ntg f 77.33 0.0   1   0.0 0.0 77.33, 77.33 2.38
(B6.5XFAD x BXD65)F1-Ntg m 45.927 9.7311   4 4.8656 0.2119 35.33, 57.72 0.55
(B6.5XFAD x BXD66)F1-ADtg f 32.0 0.0   1   0.0 0.0 32.0, 32.0 -0.52
(B6.5XFAD x BXD66)F1-ADtg m 57.17 12.912   4 6.4558 0.2259 39.33, 66.67 1.23
(B6.5XFAD x BXD66)F1-Ntg f 48.0 0.0   1   0.0 0.0 48.0, 48.0 0.5
(B6.5XFAD x BXD66)F1-Ntg m 39.33 0.0   1   0.0 0.0 39.33, 39.33 0.15
(B6.5XFAD x BXD68)F1-ADtg f 34.668 15.482   6 6.3206 0.4466 11.33, 56.67 -0.35
(B6.5XFAD x BXD68)F1-ADtg m 56.0 0.0   1   0.0 0.0 56.0, 56.0 1.16
(B6.5XFAD x BXD68)F1-Ntg f 54.79 13.348   9 4.4493 0.2436 34.0, 76.67 0.93
(B6.5XFAD x BXD68)F1-Ntg m 53.0 15.556   2   11.0 0.2935 42.0, 64.0 0.98
(B6.5XFAD x BXD69)F1-ADtg f 43.335 7.5448   2   5.335 0.1741 38.0, 48.67 0.2
(B6.5XFAD x BXD69)F1-ADtg m 56.67 0.0   1   0.0 0.0 56.67, 56.67 1.2
(B6.5XFAD x BXD69)F1-Ntg f 44.67 0.0   1   0.0 0.0 44.67, 44.67 0.29
(B6.5XFAD x BXD75)F1-ADtg f 18.52 13.771   4 6.8853 0.7436 2.67, 31.33 -1.39
(B6.5XFAD x BXD75)F1-ADtg m 5.665 8.0115   2   5.665 1.4142 -1.9
(B6.5XFAD x BXD75)F1-Ntg f 31.43 27.446   3 15.846 0.8733 -0.56
(B6.5XFAD x BXD75)F1-Ntg m 15.33 0.0   1   0.0 0.0 15.33, 15.33 -1.31
(B6.5XFAD x BXD77)F1-ADtg f 44.145 0.74246   2   0.525 0.0168 43.62, 44.67 0.25
(B6.5XFAD x BXD77)F1-ADtg m 12.67 0.0   1   0.0 0.0 12.67, 12.67 -1.47
(B6.5XFAD x BXD77)F1-Ntg f 21.335 10.373   2   7.335 0.4862 14.0, 28.67 -1.21
(B6.5XFAD x BXD77)F1-Ntg m 15.665 0.47376   2   0.335 0.0302 15.33, 16.0 -1.29
(B6.5XFAD x BXD81)F1-ADtg f 19.372 16.243   6 6.6311 0.8385 -1.33
(B6.5XFAD x BXD81)F1-Ntg f 30.223 26.734   3 15.435 0.8846 4.67, 58.0 -0.64
(B6.5XFAD x BXD87)F1-ADtg f 44.667 34.144   3 19.713 0.7644 6.0, 70.67 0.29
(B6.5XFAD x BXD87)F1-ADtg m 50.0 0.0   1   0.0 0.0 50.0, 50.0 0.8
(B6.5XFAD x BXD87)F1-Ntg f 43.167 17.609   3 10.167 0.4079 26.17, 61.33 0.19
(B6.5XFAD x BXD87)F1-Ntg m 25.333 43.879   3 25.333 1.7321 -0.7
(B6.5XFAD x BXD99)F1-ADtg f 54.89 8.7027   3 5.0245 0.1585 48.0, 64.67 0.94
(B6.5XFAD x D2)F1-ADtg f 34.787 22.446   16 5.6116 0.6453 -0.35
(B6.5XFAD x D2)F1-ADtg m 42.078 19.217   13 5.3298 0.4567 11.33, 76.0 0.32
(B6.5XFAD x D2)F1-Ntg f 45.031 22.507   11 6.7862 0.4998 4.67, 80.67 0.31
(B6.5XFAD x D2)F1-Ntg m 36.619 22.703   8 8.0269 0.62 6.0, 72.67 -0.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg f 46.875 13.9178 74.5054 19.2446
(B6.5XFAD x B6)F1-ADtg m 43.7186 7.4394 58.4876 28.9495
(B6.5XFAD x B6)F1-Ntg f 44.945 8.0355 60.8974 28.9926
(B6.5XFAD x B6)F1-Ntg m 46.8325 9.8414 66.3701 27.2949
(B6.5XFAD x BXD100)F1-ADtg f 33.0 9.8414 52.5376 13.4624
(B6.5XFAD x BXD100)F1-ADtg m 17.335 13.9178 44.9654 -10.2954
(B6.5XFAD x BXD32)F1-ADtg f 34.1675 9.8414 53.7051 14.6299
(B6.5XFAD x BXD32)F1-ADtg m 18.33 13.9178 45.9604 -9.3004
(B6.5XFAD x BXD44)F1-ADtg f 65.0 13.9178 92.6304 37.3696
(B6.5XFAD x BXD44)F1-ADtg m 39.93 13.9178 67.5604 12.2996
(B6.5XFAD x BXD60)F1-ADtg f 50.515 13.9178 78.1454 22.8846
(B6.5XFAD x BXD60)F1-ADtg m 34.71 13.9178 62.3404 7.0796
(B6.5XFAD x BXD61)F1-ADtg f 28.67 13.9178 56.3004 1.0396
(B6.5XFAD x BXD61)F1-ADtg m 58.85 13.9178 86.4804 31.2196
(B6.5XFAD x BXD65)F1-ADtg f 42.2233 11.3639 64.7835 19.6632
(B6.5XFAD x BXD65)F1-ADtg m 47.67 13.9178 75.3004 20.0396
(B6.5XFAD x BXD68)F1-Ntg f 54.7889 6.5609 67.814 41.7638
(B6.5XFAD x BXD68)F1-Ntg m 53.0 13.9178 80.6304 25.3696
(B6.5XFAD x BXD75)F1-ADtg f 18.52 9.8414 38.0576 -1.0176
(B6.5XFAD x BXD75)F1-ADtg m 5.665 13.9178 33.2954 -21.9654
(B6.5XFAD x BXD77)F1-Ntg f 21.335 13.9178 48.9654 -6.2954
(B6.5XFAD x BXD77)F1-Ntg m 15.665 13.9178 43.2954 -11.9654
(B6.5XFAD x BXD87)F1-Ntg f 43.1667 11.3639 65.7268 20.6065
(B6.5XFAD x BXD87)F1-Ntg m 25.3333 11.3639 47.8935 2.7732
(B6.5XFAD x D2)F1-ADtg f 34.7869 4.9207 44.5557 25.0181
(B6.5XFAD x D2)F1-ADtg m 42.0777 5.459 52.9152 31.2402
(B6.5XFAD x D2)F1-Ntg f 45.0309 5.9346 56.8125 33.2493
(B6.5XFAD x D2)F1-Ntg m 36.6187 6.9589 50.4339 22.8036


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
(B6.5XFAD x B6)F1-ADtg both 45.2968 7.8907 60.9617 29.6318
(B6.5XFAD x B6)F1-Ntg both 45.8887 6.3526 58.5002 33.2773
(B6.5XFAD x BXD100)F1-ADtg both 25.1675 8.5229 42.0876 8.2474
(B6.5XFAD x BXD32)F1-ADtg both 26.2487 8.5229 43.1688 9.3287
(B6.5XFAD x BXD44)F1-ADtg both 52.465 9.8414 72.0026 32.9274
(B6.5XFAD x BXD60)F1-ADtg both 42.6125 9.8414 62.1501 23.0749
(B6.5XFAD x BXD61)F1-ADtg both 43.76 9.8414 63.2976 24.2224
(B6.5XFAD x BXD65)F1-ADtg both 44.9467 8.9839 62.782 27.1113
(B6.5XFAD x BXD68)F1-Ntg both 53.8944 7.6934 69.1677 38.6212
(B6.5XFAD x BXD75)F1-ADtg both 12.0925 8.5229 29.0126 -4.8276
(B6.5XFAD x BXD77)F1-Ntg both 18.5 9.8414 38.0376 -1.0376
(B6.5XFAD x BXD87)F1-Ntg both 34.25 8.0355 50.2024 18.2976
(B6.5XFAD x D2)F1-ADtg both 38.4323 3.6747 45.7275 31.137
(B6.5XFAD x D2)F1-Ntg both 40.8248 4.5729 49.9032 31.7465




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA