Project measure / variable:   Lesage1   CD4_neg_CD8_pos_of_tot

ID, description, units MPD:63519   CD4_neg_CD8_pos_of_tot   percentage of splenic lymphocytes that are CD8+ T cells   [%]  
Data set, strains Lesage1   CC w/par   76 strains     sex: both     age: 5-8wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Lesage1 - percentage of splenic lymphocytes that are CD8+ T cells



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested46 strains65 strains
Mean of the strain means8.9359   % 9.1038   %
Median of the strain means7.425   % 7.93   %
SD of the strain means± 3.9968 ± 4.5939
Coefficient of variation (CV)0.4473 0.5046
Min–max range of strain means1.815   –   20.65   % 1.9   –   23.6   %
Mean sample size per strain2.2   mice 2.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3.5653 3.5653 2.1089 0.1551
strain 12 439.4797 36.6233 21.663 < 0.0001
sex:strain 12 15.4365 1.2864 0.7609 0.6845
Residuals 36 60.8613 1.6906


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.01 1.8668   2   1.32 0.2663 5.69, 8.33 -0.48
129S1/SvImJ m 9.635 2.0718   2   1.465 0.215 8.17, 11.1 0.12
A/J f 4.78 0.05657   2   0.04 0.0118 4.74, 4.82 -1.04
A/J m 5.18 0.08485   2   0.06 0.0164 5.12, 5.24 -0.85
C57BL/6J f 8.455 2.6818   4 1.3409 0.3172 5.96, 11.6 -0.12
C57BL/6J m 10.4 0.0   1   0.0 0.0 10.4, 10.4 0.28
CAST/EiJ f 1.815 0.24749   2   0.175 0.1364 1.64, 1.99 -1.78
CAST/EiJ m 1.9 0.42426   2   0.3 0.2233 1.6, 2.2 -1.57
CC008/Geni m 4.7833 2.5731   3 1.4856 0.5379 2.98, 7.73 -0.94
CC010/Geni f 20.65 0.6364   2   0.45 0.0308 20.2, 21.1 2.93
CC010/Geni m 23.6 0.0   1   0.0 0.0 23.6, 23.6 3.16
CC012/Geni f 5.575 0.95459   2   0.675 0.1712 4.9, 6.25 -0.84
CC012/Geni m 5.3267 0.9487   3 0.54773 0.1781 4.24, 5.99 -0.82
CC013/Geni m 7.93 0.59632   3 0.34429 0.0752 7.29, 8.47 -0.26
CC016/Geni m 18.633 0.90738   3 0.52387 0.0487 17.8, 19.6 2.07
CC020/Geni f 6.62 0.0   1   0.0 0.0 6.62, 6.62 -0.58
CC020/Geni m 5.875 0.79903   2   0.565 0.136 5.31, 6.44 -0.7
CC023/Geni m 4.43 0.68352   3 0.39463 0.1543 3.79, 5.15 -1.02
CC024/Geni f 12.45 1.7678   2   1.25 0.142 11.2, 13.7 0.88
CC024/Geni m 7.41 0.0   1   0.0 0.0 7.41, 7.41 -0.37
CC025/Geni f 13.467 0.32146   3 0.18559 0.0239 13.1, 13.7 1.13
CC026/Geni m 8.58 0.77929   3 0.44993 0.0908 7.69, 9.14 -0.11
CC027/Geni f 12.9 0.0   1   0.0 0.0 12.9, 12.9 0.99
CC027/Geni m 16.0 1.2728   2   0.9 0.0795 15.1, 16.9 1.5
CC030/Geni f 4.585 1.393   2   0.985 0.3038 3.6, 5.57 -1.09
CC031/Geni f 10.2 0.0   1   0.0 0.0 10.2, 10.2 0.32
CC031/Geni m 10.5 0.42426   2   0.3 0.0404 10.2, 10.8 0.3
CC032/Geni m 4.1733 0.24786   3 0.1431 0.0594 3.89, 4.35 -1.07
CC033/Geni f 4.8 0.25515   3 0.14731 0.0532 4.55, 5.06 -1.03
CC038/Geni f 7.025 0.20506   2   0.145 0.0292 6.88, 7.17 -0.48
CC038/Geni m 6.16 0.0   1   0.0 0.0 6.16, 6.16 -0.64
CC042/Geni m 5.9233 0.08737   3 0.05044 0.0147 5.85, 6.02 -0.69
CC043/Geni m 7.61 0.73021   3 0.42158 0.096 7.03, 8.43 -0.33
CC056/Geni f 12.2 0.0   1   0.0 0.0 12.2, 12.2 0.82
CC056/Geni m 10.05 0.07071   2   0.05 0.007 10.0, 10.1 0.21
CC061/Geni m 14.8 1.9468   3 1.124 0.1315 13.3, 17.0 1.24
CIV2_FE f 6.0667 0.43822   3 0.253 0.0722 5.77, 6.57 -0.72
DET3_GA m 8.3433 0.89673   3 0.51773 0.1075 7.39, 9.17 -0.17
DONNELL_HA f 11.0 0.28284   2   0.2 0.0257 10.8, 11.2 0.52
DONNELL_HA m 10.13 1.2733   3 0.73514 0.1257 9.37, 11.6 0.22
FIV_AC m 22.975 1.7877   4 0.89384 0.0778 20.7, 24.8 3.02
FUF_HE f 7.2533 0.52937   3 0.30563 0.073 6.65, 7.64 -0.42
GALASUPREME_CE m 8.4267 0.98027   3 0.56596 0.1163 7.46, 9.42 -0.15
GIT_GC f 6.27 0.0   1   0.0 0.0 6.27, 6.27 -0.67
GIT_GC m 5.76 0.07071   2   0.05 0.0123 5.71, 5.81 -0.73
HAX2_EF f 8.34 0.24434   3 0.14107 0.0293 8.17, 8.62 -0.15
HAZ_FE f 7.59 0.0   1   0.0 0.0 7.59, 7.59 -0.34
HAZ_FE m 5.975 0.3182   2   0.225 0.0533 5.75, 6.2 -0.68
HIP_GA f 15.9 0.0   1   0.0 0.0 15.9, 15.9 1.74
HIP_GA m 16.2 1.6971   2   1.2 0.1048 15.0, 17.4 1.54
HOE_GC f 7.26 0.0   1   0.0 0.0 7.26, 7.26 -0.42
HOE_GC m 8.85 0.3677   2   0.26 0.0415 8.59, 9.11 -0.06
JUD_EF m 4.095 0.54495   4 0.27247 0.1331 3.33, 4.62 -1.09
KAV_AF f 4.065 0.00707107   2   0.005 0.0017 4.06, 4.07 -1.22
KAV_AF m 3.52 0.0   1   0.0 0.0 3.52, 3.52 -1.22
LAM_DC f 15.0 0.0   1   0.0 0.0 15.0, 15.0 1.52
LAM_DC m 20.3 0.0   1   0.0 0.0 20.3, 20.3 2.44
LAT_HD f 8.01 1.7336   5 0.77529 0.2164 6.55, 10.9 -0.23
LAT_HD m 10.18 1.1597   2   0.82 0.1139 9.36, 11.0 0.23
LAX_FC m 4.545 0.41719   2   0.295 0.0918 4.25, 4.84 -0.99
LEL_FH m 5.91 1.1031   2   0.78 0.1866 5.13, 6.69 -0.7
LIP_BG f 14.0 0.46904   4 0.23452 0.0335 13.4, 14.5 1.27
LIP_BG m 11.9 0.0   1   0.0 0.0 11.9, 11.9 0.61
LIV_DA f 16.1 0.0   1   0.0 0.0 16.1, 16.1 1.79
LIV_DA m 12.2 0.98995   2   0.7 0.0811 11.5, 12.9 0.67
LOD_AE f 6.5767 0.82373   3 0.47558 0.1253 5.89, 7.49 -0.59
LOM_BG m 11.777 1.5993   3 0.92333 0.1358 9.93, 12.7 0.58
LOT_FC f 6.9033 0.24786   3 0.1431 0.0359 6.62, 7.08 -0.51
LOT_FC m 6.24 1.3152   2   0.93 0.2108 5.31, 7.17 -0.62
LOX_GF m 17.433 0.47258   3 0.27285 0.0271 16.9, 17.8 1.81
LUF_AD m 7.488 3.2709   5 1.4628 0.4368 4.82, 12.2 -0.35
LUG_EH m 7.1067 2.5494   3 1.4719 0.3587 5.19, 10.0 -0.43
LUS_AH f 5.79 0.26627   3 0.15373 0.046 5.54, 6.07 -0.79
LUV_DG m 13.925 0.51235   4 0.25617 0.0368 13.4, 14.5 1.05
LUZ_FH f 6.04 0.25456   2   0.18 0.0421 5.86, 6.22 -0.72
LUZ_FH m 6.16 0.0   1   0.0 0.0 6.16, 6.16 -0.64
MERCURI_HF m 8.46 0.43405   3 0.2506 0.0513 7.96, 8.74 -0.14
NOD/ShiLtJ f 10.81 1.5415   2   1.09 0.1426 9.72, 11.9 0.47
NOD/ShiLtJ m 11.0 0.84853   2   0.6 0.0771 10.4, 11.6 0.41
NZO/HlLtJ f 4.74 1.7819   2   1.26 0.3759 3.48, 6.0 -1.05
NZO/HlLtJ m 5.705 0.03536   2   0.025 0.0062 5.68, 5.73 -0.74
PAT_CD m 10.69 0.62554   3 0.36116 0.0585 9.97, 11.1 0.35
PEF_EC f 11.343 1.7403   3 1.0048 0.1534 9.53, 13.0 0.6
PEF_EC m 11.6 0.98489   3 0.56862 0.0849 10.8, 12.7 0.54
POH_DC f 8.83 1.3709   3 0.79148 0.1553 7.87, 10.4 -0.03
PWK/PhJ f 5.405 0.65761   2   0.465 0.1217 4.94, 5.87 -0.88
PWK/PhJ m 5.155 1.987   2   1.405 0.3854 3.75, 6.56 -0.86
SEH_AH f 15.5 0.0   1   0.0 0.0 15.5, 15.5 1.64
SEH_AH m 12.8 0.0   1   0.0 0.0 12.8, 12.8 0.8
STUCKY_HF f 7.0967 2.0887   3 1.2059 0.2943 4.94, 9.11 -0.46
STUCKY_HF m 5.62 0.0   1   0.0 0.0 5.62, 5.62 -0.76
VIT_ED f 13.567 0.65064   3 0.37565 0.048 12.9, 14.2 1.16
VUX2_HF m 6.2633 0.67099   3 0.3874 0.1071 5.65, 6.98 -0.62
WAD f 6.0633 0.63446   3 0.3663 0.1046 5.39, 6.65 -0.72
WSB/EiJ f 7.955 1.8314   2   1.295 0.2302 6.66, 9.25 -0.25
WSB/EiJ m 9.345 2.9062   2   2.055 0.311 7.29, 11.4 0.05
XAD8_BG f 13.0 0.0   1   0.0 0.0 13.0, 13.0 1.02
XAD8_BG m 10.4 0.43589   3 0.25166 0.0419 10.1, 10.9 0.28
XAH3_GH m 4.9333 0.50013   3 0.28875 0.1014 4.36, 5.28 -0.91
XAS4_AF m 11.7 0.36056   3 0.20817 0.0308 11.3, 12.0 0.57
XAV_AH m 6.4633 0.60476   3 0.34916 0.0936 6.01, 7.15 -0.57
XAW2_CD m 11.34 2.0648   2   1.46 0.1821 9.88, 12.8 0.49
XEB2_AG f 5.2 0.7496   3 0.43278 0.1442 4.38, 5.85 -0.93
XEB2_AG m 6.2767 0.05033   3 0.02906 0.008 6.23, 6.33 -0.62
XEB_AF f 7.245 1.1384   2   0.805 0.1571 6.44, 8.05 -0.42
XEB_AF m 7.17 0.0   1   0.0 0.0 7.17, 7.17 -0.42
XEQ_EH m 11.067 1.0263   3 0.59255 0.0927 10.2, 12.2 0.43
XXEN2_DC m 5.8133 0.38553   3 0.22259 0.0663 5.49, 6.24 -0.72
XXEN3_DC f 9.6 0.0   1   0.0 0.0 9.6, 9.6 0.17
XXEN3_DC m 6.9 0.0   1   0.0 0.0 6.9, 6.9 -0.48
YOX_DE m 4.7033 0.33546   3 0.19368 0.0713 4.49, 5.09 -0.96


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.01 0.9194 8.8746 5.1454
129S1/SvImJ m 9.635 0.9194 11.4996 7.7704
A/J f 4.78 0.9194 6.6446 2.9154
A/J m 5.18 0.9194 7.0446 3.3154
CAST/EiJ f 1.815 0.9194 3.6796 -0.0496
CAST/EiJ m 1.9 0.9194 3.7646 0.0354
CC012/Geni f 5.575 0.9194 7.4396 3.7104
CC012/Geni m 5.3267 0.7507 6.8491 3.8042
DONNELL_HA f 11.0 0.9194 12.8646 9.1354
DONNELL_HA m 10.13 0.7507 11.6525 8.6075
LAT_HD f 8.01 0.5815 9.1893 6.8307
LAT_HD m 10.18 0.9194 12.0446 8.3154
LOT_FC f 6.9033 0.7507 8.4258 5.3809
LOT_FC m 6.24 0.9194 8.1046 4.3754
NOD/ShiLtJ f 10.81 0.9194 12.6746 8.9454
NOD/ShiLtJ m 11.0 0.9194 12.8646 9.1354
NZO/HlLtJ f 4.74 0.9194 6.6046 2.8754
NZO/HlLtJ m 5.705 0.9194 7.5696 3.8404
PEF_EC f 11.3433 0.7507 12.8658 9.8209
PEF_EC m 11.6 0.7507 13.1225 10.0775
PWK/PhJ f 5.405 0.9194 7.2696 3.5404
PWK/PhJ m 5.155 0.9194 7.0196 3.2904
WSB/EiJ f 7.955 0.9194 9.8196 6.0904
WSB/EiJ m 9.345 0.9194 11.2096 7.4804
XEB2_AG f 5.2 0.7507 6.7225 3.6775
XEB2_AG m 6.2767 0.7507 7.7991 4.7542


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8.3225 0.6501 9.641 7.004
A/J both 4.98 0.6501 6.2985 3.6615
CAST/EiJ both 1.8575 0.6501 3.176 0.539
CC012/Geni both 5.4508 0.5935 6.6544 4.2472
DONNELL_HA both 10.565 0.5935 11.7686 9.3614
LAT_HD both 9.095 0.5439 10.1981 7.9919
LOT_FC both 6.5717 0.5935 7.7753 5.3681
NOD/ShiLtJ both 10.905 0.6501 12.2235 9.5865
NZO/HlLtJ both 5.2225 0.6501 6.541 3.904
PEF_EC both 11.4717 0.5308 12.5482 10.3951
PWK/PhJ both 5.28 0.6501 6.5985 3.9615
WSB/EiJ both 8.65 0.6501 9.9685 7.3315
XEB2_AG both 5.7383 0.5308 6.8149 4.6618




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA