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Project measure / variable:   GMC17   pip_18

ID, description, units MPD:56614   pip_18   auditory brainstem response (ABR) threshold, sound pressure level   [dB]  18 kHz sound stimulus  
Data set, strains GMC17   inbred w/CC7   7 strains     sex: both     age: 17-18wks
Procedure ABR test
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  STRAIN COMPARISON PLOT
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GMC17 - auditory brainstem response (ABR) threshold, sound pressure level 18 kHz sound stimulus



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means60.3   dB 57.3   dB
Median of the strain means42.2   dB 32.2   dB
SD of the strain means± 32.1 ± 33.3
Coefficient of variation (CV)0.532 0.582
Min–max range of strain means27.5   –   100   dB 30.0   –   100   dB
Mean sample size per strain13.0   mice 13.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 969.2308 969.2308 3.5917 0.0598
strain 6 162550.6407 27091.7735 100.3951 < 0.0001
sex:strain 6 652.2267 108.7045 0.4028 0.8764
Residuals 168 45335.0446 269.8515


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 37.2 5.15   16 1.29 0.139 30.0, 45.0 -0.72
129S1/SvImJ m 31.2 5.92   16 1.48 0.189 20.0, 45.0 -0.78
A/J f 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.24
A/J m 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.28
C57BL/6J f 42.2 13.8   16 3.45 0.327 20.0, 65.0 -0.56
C57BL/6J m 32.2 7.06   16 1.77 0.219 20.0, 45.0 -0.75
CAST/EiJ f 34.4 11.5   8 4.06 0.334 25.0, 55.0 -0.81
CAST/EiJ m 32.1 11.1   7 4.21 0.346 20.0, 50.0 -0.76
NOD/ShiLtJ f 100.0 0.0   17 0.0 0.0 100.0, 100.0 1.24
NOD/ShiLtJ m 100.0 0.0   16 0.0 0.0 100.0, 100.0 1.28
NZO/HlLtJ f 80.6 34.7   16 8.67 0.43 20.0, 100.0 0.63
NZO/HlLtJ m 75.6 37.4   16 9.34 0.494 20.0, 100.0 0.55
WSB/EiJ f 27.5 3.54   2   2.5 0.129 25.0, 30.0 -1.02
WSB/EiJ m 30.0 7.07   4 3.54 0.236 25.0, 40.0 -0.82


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 37.1875 4.1068 45.2951 29.0799
129S1/SvImJ m 31.25 4.1068 39.3576 23.1424
A/J f 100.0 4.1068 108.1076 91.8924
A/J m 100.0 4.1068 108.1076 91.8924
C57BL/6J f 42.1875 4.1068 50.2951 34.0799
C57BL/6J m 32.1875 4.1068 40.2951 24.0799
CAST/EiJ f 34.375 5.8079 45.8408 22.9092
CAST/EiJ m 32.1429 6.2089 44.4003 19.8854
NOD/ShiLtJ f 100.0 3.9842 107.8655 92.1345
NOD/ShiLtJ m 100.0 4.1068 108.1076 91.8924
NZO/HlLtJ f 80.625 4.1068 88.7326 72.5174
NZO/HlLtJ m 75.625 4.1068 83.7326 67.5174
WSB/EiJ f 27.5 11.6158 50.4316 4.5684
WSB/EiJ m 30.0 8.2136 46.2151 13.7849


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 34.2188 2.9039 39.9517 28.4858
A/J both 100.0 2.9039 105.7329 94.2671
C57BL/6J both 37.1875 2.9039 42.9204 31.4546
CAST/EiJ both 33.2589 4.2509 41.6511 24.8668
NOD/ShiLtJ both 100.0 2.8609 105.648 94.352
NZO/HlLtJ both 78.125 2.9039 83.8579 72.3921
WSB/EiJ both 28.75 7.1132 42.7927 14.7073




  GWAS USING LINEAR MIXED MODELS