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Project measure / variable:   GMC11   GLU_15

ID, description, units MPD:56012   GLU_15   intraperitoneal glucose tolerance test (20% glucose i.p., 16h fast)   [mmol/L]  at 15 min  
Data set, strains GMC11   inbred   6 strains     sex: both     age: 13-14wks
Procedure glucose tolerance
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  STRAIN COMPARISON PLOT
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GMC11 - intraperitoneal glucose tolerance test (20% glucose i.p., 16h fast) at 15 min



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested6 strains6 strains
Mean of the strain means14.0   mmol/L 16.6   mmol/L
Median of the strain means13.0   mmol/L 16.4   mmol/L
SD of the strain means± 3.70 ± 3.60
Coefficient of variation (CV)0.263 0.217
Min–max range of strain means10.3   –   20.9   mmol/L 12.0   –   22.2   mmol/L
Mean sample size per strain13.8   mice 15.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 123.8224 123.8224 9.2973 0.0027
strain 4 1939.2042 484.801 36.4018 < 0.0001
sex:strain 4 36.3747 9.0937 0.6828 0.6049
Residuals 153 2037.6611 13.318


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 10.3 1.51   16 0.377 0.146 7.72, 13.2 -1.01
129S1/SvImJ m 12.0 3.25   16 0.812 0.271 6.49, 17.0 -1.29
A/J f 12.3 1.73   15 0.446 0.14 10.3, 16.9 -0.47
A/J m 14.1 3.59   16 0.896 0.255 8.33, 22.1 -0.7
C57BL/6J f 20.9 2.45   16 0.612 0.117 16.1, 24.9 1.85
C57BL/6J m 22.2 3.91   16 0.977 0.176 15.7, 29.1 1.55
NOD/ShiLtJ f 14.9 5.37   18 1.27 0.36 5.05, 27.2 0.23
NOD/ShiLtJ m 15.6 3.1   16 0.776 0.199 11.0, 21.4 -0.29
NZO/HlLtJ f 13.7 3.55   17 0.86 0.26 6.77, 20.4 -0.09
NZO/HlLtJ m 17.1 5.34   17 1.29 0.312 11.2, 32.4 0.13
PWK/PhJ f 12.2 0.0   1   0.0 0.0 12.2, 12.2 -0.5
PWK/PhJ m 18.8 3.88   12 1.12 0.207 9.49, 23.5 0.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 10.3194 0.9123 12.1218 8.517
129S1/SvImJ m 11.9925 0.9123 13.7949 10.1901
A/J f 12.3333 0.9423 14.1949 10.4718
A/J m 14.0825 0.9123 15.8849 12.2801
C57BL/6J f 20.905 0.9123 22.7074 19.1026
C57BL/6J m 22.2144 0.9123 24.0168 20.412
NOD/ShiLtJ f 14.93 0.8602 16.6293 13.2307
NOD/ShiLtJ m 15.5625 0.9123 17.3649 13.7601
NZO/HlLtJ f 13.6612 0.8851 15.4098 11.9126
NZO/HlLtJ m 17.0988 0.8851 18.8474 15.3502


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 11.1559 0.6451 12.4304 9.8814
A/J both 13.2079 0.6558 14.5035 11.9123
C57BL/6J both 21.5597 0.6451 22.8342 20.2852
NOD/ShiLtJ both 15.2463 0.627 16.4848 14.0077
NZO/HlLtJ both 15.38 0.6259 16.6165 14.1435




  GWAS USING LINEAR MIXED MODELS