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Project measure / variable:   GMC04   LatFall_3

ID, description, units MPD:55313   LatFall_3   latency to fall from accelerating rotarod (8rpm/min)   [s]  trial3  
Data set, strains GMC04   inbred w/CC7   7 strains     sex: both     age: 9-10wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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GMC04 - latency to fall from accelerating rotarod (8rpm/min) trial3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means172   s 144   s
Median of the strain means190   s 155   s
SD of the strain means± 48.9 ± 41.2
Coefficient of variation (CV)0.285 0.287
Min–max range of strain means89.2   –   235   s 86.1   –   200   s
Mean sample size per strain17.4   mice 17.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 48850.8333 48850.8333 7.5049 0.0066
strain 6 376386.9057 62731.1509 9.6373 < 0.0001
sex:strain 6 55307.6319 9217.9387 1.4161 0.2092
Residuals 228 1484091.1291 6509.1716


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 130.0 51.7   16 12.9 0.396 70.0, 279.0 -0.86
129S1/SvImJ m 155.0 48.0   16 12.0 0.309 75.0, 288.0 0.28
A/J f 89.2 23.3   16 5.83 0.261 59.0, 138.0 -1.69
A/J m 86.1 39.1   16 9.77 0.454 19.0, 148.0 -1.4
C57BL/6J f 190.0 71.6   16 17.9 0.378 56.0, 276.0 0.37
C57BL/6J m 175.0 73.5   16 18.4 0.42 41.0, 287.0 0.76
CAST/EiJ f 164.0 88.2   19 20.2 0.537 53.0, 300.0 -0.16
CAST/EiJ m 104.0 61.4   17 14.9 0.588 -0.96
NOD/ShiLtJ f 204.0 111.0   18 26.2 0.546 8.0, 300.0 0.66
NOD/ShiLtJ m 165.0 128.0   16 32.1 0.778 7.0, 300.0 0.52
NZO/HlLtJ f 191.0 35.9   17 8.7 0.188 133.0, 255.0 0.39
NZO/HlLtJ m 120.0 72.4   17 17.6 0.604 12.0, 208.0 -0.57
PWK/PhJ f 235.0 93.5   20 20.9 0.397 29.0, 300.0 1.29
PWK/PhJ m 200.0 118.0   22 25.2 0.589 1.37


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 130.375 20.1699 170.1182 90.6318
129S1/SvImJ m 155.375 20.1699 195.1182 115.6318
A/J f 89.25 20.1699 128.9932 49.5068
A/J m 86.125 20.1699 125.8682 46.3818
C57BL/6J f 189.5 20.1699 229.2432 149.7568
C57BL/6J m 175.125 20.1699 214.8682 135.3818
CAST/EiJ f 164.2105 18.5091 200.6813 127.7397
CAST/EiJ m 104.3529 19.5676 142.9095 65.7964
NOD/ShiLtJ f 203.6111 19.0163 241.0813 166.1409
NOD/ShiLtJ m 165.0625 20.1699 204.8057 125.3193
NZO/HlLtJ f 191.2353 19.5676 229.7918 152.6788
NZO/HlLtJ m 119.8824 19.5676 158.4389 81.3258
PWK/PhJ f 235.35 18.0405 270.8974 199.8026
PWK/PhJ m 200.5 17.2009 234.3931 166.6069


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 142.875 14.2622 170.9777 114.7723
A/J both 87.6875 14.2622 115.7902 59.5848
C57BL/6J both 182.3125 14.2622 210.4152 154.2098
CAST/EiJ both 134.2817 13.4674 160.8182 107.7453
NOD/ShiLtJ both 184.3368 13.8604 211.6477 157.0259
NZO/HlLtJ both 155.5588 13.8364 182.8224 128.2952
PWK/PhJ both 217.925 12.4632 242.4829 193.3671




  GWAS USING LINEAR MIXED MODELS