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Project measure / variable:   GMC02   all_paws1

ID, description, units MPD:55121   all_paws1   forelimb and hindlimb grip strength   [g]  trial1  
Data set, strains GMC02   inbred w/CC8   8 strains     sex: both     age: 8-10wks
Procedure grip strength
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  STRAIN COMPARISON PLOT
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GMC02 - forelimb and hindlimb grip strength trial1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means188   g 208   g
Median of the strain means190   g 219   g
SD of the strain means± 32.4 ± 38.3
Coefficient of variation (CV)0.172 0.184
Min–max range of strain means150   –   233   g 159   –   254   g
Mean sample size per strain17.4   mice 16.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 25603.4017 25603.4017 44.5278 < 0.0001
strain 7 298021.5978 42574.514 74.0429 < 0.0001
sex:strain 7 7757.7908 1108.2558 1.9274 0.0656
Residuals 258 148349.4287 574.9978


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 180.0 16.7   16 4.16 0.0926 155.0, 215.0 -0.26
129S1/SvImJ m 221.0 23.6   16 5.91 0.107 187.0, 266.0 0.34
A/J f 214.0 34.5   16 8.64 0.162 149.0, 278.0 0.79
A/J m 230.0 26.2   16 6.55 0.114 183.0, 264.0 0.58
C57BL/6J f 219.0 26.4   16 6.59 0.12 178.0, 258.0 0.95
C57BL/6J m 248.0 37.9   16 9.47 0.153 195.0, 316.0 1.05
CAST/EiJ f 157.0 14.1   19 3.24 0.0901 135.0, 185.0 -0.97
CAST/EiJ m 159.0 20.1   17 4.88 0.127 114.0, 197.0 -1.28
NOD/ShiLtJ f 233.0 33.7   18 7.94 0.144 182.0, 276.0 1.38
NOD/ShiLtJ m 254.0 20.5   16 5.12 0.0805 218.0, 286.0 1.21
NZO/HlLtJ f 199.0 18.2   17 4.42 0.0918 172.0, 238.0 0.33
NZO/HlLtJ m 217.0 22.0   17 5.35 0.102 175.0, 252.0 0.24
PWK/PhJ f 155.0 18.7   19 4.29 0.121 130.0, 191.0 -1.03
PWK/PhJ m 171.0 19.6   21 4.27 0.114 144.0, 214.0 -0.96
WSB/EiJ f 150.0 19.2   18 4.53 0.128 101.0, 179.0 -1.19
WSB/EiJ m 163.0 21.1   16 5.28 0.13 122.0, 198.0 -1.17


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 179.8125 5.9948 191.6174 168.0076
129S1/SvImJ m 221.3125 5.9948 233.1174 209.5076
A/J f 213.6875 5.9948 225.4924 201.8826
A/J m 230.125 5.9948 241.9299 218.3201
C57BL/6J f 219.4375 5.9948 231.2424 207.6326
C57BL/6J m 248.1875 5.9948 259.9924 236.3826
CAST/EiJ f 156.5789 5.5012 167.4119 145.746
CAST/EiJ m 159.0588 5.8158 170.5113 147.6064
NOD/ShiLtJ f 233.2778 5.6519 244.4076 222.148
NOD/ShiLtJ m 254.5 5.9948 266.3049 242.6951
NZO/HlLtJ f 198.7647 5.8158 210.2172 187.3122
NZO/HlLtJ m 217.1765 5.8158 228.6289 205.724
PWK/PhJ f 154.7895 5.5012 165.6224 143.9565
PWK/PhJ m 171.4762 5.2327 181.7804 161.172
WSB/EiJ f 150.0556 5.6519 161.1853 138.9258
WSB/EiJ m 162.5625 5.9948 174.3674 150.7576


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 200.5625 4.2389 208.9098 192.2152
A/J both 221.9063 4.2389 230.2536 213.5589
C57BL/6J both 233.8125 4.2389 242.1598 225.4652
CAST/EiJ both 157.8189 4.0027 165.701 149.9368
NOD/ShiLtJ both 243.8889 4.1195 252.001 235.7767
NZO/HlLtJ both 207.9706 4.1124 216.0687 199.8725
PWK/PhJ both 163.1328 3.7962 170.6083 155.6574
WSB/EiJ both 156.309 4.1195 164.4212 148.1969




  GWAS USING LINEAR MIXED MODELS