Project measure / variable:   Shimomura2   DD_amplitude

ID, description, units MPD:52702   DD_amplitude   amplitude of circadian rhythm in constant darkness   [%]  
Data set, strains Shimomura2   inbred w/CC7   38 strains     sex: both     age: 10wks
Procedure monitoring system
Ontology mappings

  STRAIN COMPARISON PLOT
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Shimomura2 - amplitude of circadian rhythm in constant darkness



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested38 strains38 strains
Mean of the strain means10.2   % 9.49   %
Median of the strain means10.8   % 10.4   %
SD of the strain means± 4.13 ± 4.19
Coefficient of variation (CV)0.403 0.441
Min–max range of strain means0.250   –   17.3   % 0.786   –   18.6   %
Mean sample size per strain9.5   mice 8.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 195.9648 195.9648 7.5117 0.0063
strain 36 8179.5623 227.2101 8.7094 < 0.0001
sex:strain 36 1209.6349 33.601 1.288 0.1245
Residuals 604 15757.122 26.088


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.94 3.92   18 0.923 0.493 1.6, 15.5 -0.56
129S1/SvImJ m 6.66 4.05   18 0.955 0.609 1.6, 14.3 -0.68
A/J f 10.0 5.79   15 1.49 0.578 0.7, 19.2 -0.06
A/J m 11.2 5.69   12 1.64 0.508 4.0, 21.7 0.41
AKR/J f 5.51 3.51   12 1.01 0.637 2.4, 13.8 -1.14
AKR/J m 7.64 5.09   7 1.92 0.665 2.2, 18.1 -0.44
BALB/cByJ f 13.0 3.79   10 1.2 0.291 7.6, 17.4 0.67
BALB/cByJ m 11.8 4.38   10 1.39 0.373 1.4, 16.6 0.55
BTBR T+ Itpr3tf/J f 15.8 4.9   14 1.31 0.31 7.1, 23.7 1.35
BTBR T+ Itpr3tf/J m 14.4 8.44   10 2.67 0.587 0.4, 22.6 1.17
BUB/BnJ f 5.68 4.19   6 1.71 0.738 0.8, 10.3 -1.1
BUB/BnJ m 5.76 2.66   5 1.19 0.461 3.2, 9.6 -0.89
C3H/HeJ f 10.7 5.61   13 1.56 0.527 0.5, 17.5 0.11
C3H/HeJ m 9.46 6.76   11 2.04 0.714 1.5, 19.6 -0.01
C57BL/10J f 11.0 4.63   8 1.64 0.419 4.8, 17.3 0.19
C57BL/10J m 13.0 4.08   7 1.54 0.314 8.6, 19.6 0.84
C57BL/6J f 17.3 4.57   15 1.18 0.265 8.0, 23.2 1.71
C57BL/6J m 15.4 5.91   11 1.78 0.384 1.4, 24.4 1.41
C57BLKS/J f 6.09 3.69   7 1.39 0.606 1.5, 10.9 -1.0
C57BLKS/J m 4.72 1.68   4 0.84 0.356 3.0, 6.8 -1.14
C57BR/cdJ f 13.2 6.75   12 1.95 0.51 3.4, 22.6 0.72
C57BR/cdJ m 5.02 1.59   12 0.459 0.316 2.1, 7.4 -1.07
C57L/J f 14.5 7.13   6 2.91 0.491 5.8, 23.8 1.03
C57L/J m 10.9 5.52   22 1.18 0.505 3.7, 22.9 0.34
C58/J f 7.13 4.83   10 1.53 0.677 0.8, 13.7 -0.75
C58/J m 10.4 6.33   14 1.69 0.606 0.2, 18.7 0.22
CAST/EiJ f 13.1 5.26   16 1.31 0.401 4.8, 22.2 0.7
CAST/EiJ m 13.1 6.85   9 2.28 0.525 4.1, 21.5 0.86
CBA/J f 10.8 7.28   7 2.75 0.671 2.7, 20.5 0.14
CBA/J m 14.5 3.99   8 1.41 0.275 7.7, 20.7 1.2
CZECHII/EiJ f 14.3 6.55   10 2.07 0.459 3.5, 25.2 0.99
CZECHII/EiJ m 5.58 0.907   4 0.453 0.163 4.5, 6.7 -0.93
DBA/1J f 12.0 5.03   12 1.45 0.419 0.2, 18.6 0.43
DBA/1J m 11.1 2.63   10 0.83 0.236 7.9, 16.5 0.38
DBA/2J f 9.42 6.27   17 1.52 0.666 0.2, 20.5 -0.2
DBA/2J m 10.5 6.07   15 1.57 0.578 0.1, 18.3 0.24
FVB/NJ f 11.5 5.98   13 1.66 0.519 2.5, 20.4 0.31
FVB/NJ m 11.7 5.07   20 1.13 0.433 1.2, 18.8 0.53
I/LnJ f 7.49 3.43   7 1.29 0.458 1.8, 11.3 -0.66
I/LnJ m 9.15 3.45   6 1.41 0.377 6.0, 15.7 -0.08
JF1/MsJ f 11.3 7.22   10 2.28 0.639 2.7, 22.6 0.26
JF1/MsJ m 10.3 8.15   4 4.07 0.793 0.7, 20.5 0.19
LP/J f 7.46 4.14   11 1.25 0.554 3.0, 16.4 -0.67
LP/J m 3.56 2.78   10 0.881 0.782 1.1, 8.5 -1.42
MA/MyJ f 8.8 1.88   7 0.71 0.213 6.2, 11.1 -0.35
MA/MyJ m 9.5 6.93   2   4.9 0.729 4.6, 14.4 0.0
MOLF/EiJ f 14.5 5.27   3 3.04 0.364 10.0, 20.3 1.03
MOLF/EiJ m 11.6 2.69   2   1.9 0.232 9.7, 13.5 0.5
MSM/MsJ f 15.9 0.985   3 0.569 0.0619 14.8, 16.7 1.37
MSM/MsJ m 18.6 0.0   1   0.0 0.0 18.6, 18.6 2.18
NOD/ShiLtJ f 14.5 3.89   3 2.25 0.269 11.6, 18.9 1.03
NOD/ShiLtJ m 13.4 5.55   3 3.2 0.414 7.0, 16.9 0.93
NZB/BlNJ f 8.0 9.12   7 3.45 1.14 0.7, 21.5 -0.54
NZB/BlNJ m 0.786 0.348   7 0.132 0.444 0.3, 1.4 -2.08
NZW/LacJ f 7.65 2.61   4 1.3 0.341 4.2, 10.2 -0.63
NZW/LacJ m 4.2 3.12   4 1.56 0.743 1.5, 7.1 -1.26
PERA/EiJ f 16.4 4.42   12 1.28 0.27 9.6, 23.2 1.5
PERA/EiJ m 15.0 5.79   11 1.74 0.387 7.2, 22.7 1.32
PL/J f 4.38 3.19   4 1.59 0.728 1.6, 8.8 -1.42
PL/J m 6.45 2.19   2   1.55 0.34 4.9, 8.0 -0.73
PWK/PhJ f 11.4 6.76   5 3.02 0.592 4.5, 22.3 0.28
PWK/PhJ m 11.1 10.7   4 5.34 0.964 0.4, 25.3 0.38
RIIIS/J f 4.95 2.67   4 1.34 0.54 1.8, 8.3 -1.28
RIIIS/J m 8.17 4.38   12 1.26 0.536 2.7, 16.5 -0.32
SEA/GnJ f 9.95 3.65   12 1.06 0.367 4.6, 19.4 -0.07
SEA/GnJ m 10.2 4.61   12 1.33 0.451 4.3, 16.9 0.17
SJL/J f 3.95 4.46   14 1.19 1.13 0.2, 11.6 -1.52
SJL/J m 2.14 3.58   10 1.13 1.67 0.2, 11.8 -1.76
SM/J f 4.3 0.283   2   0.2 0.0658 4.1, 4.5 -1.44
SM/J m 3.73 0.969   6 0.396 0.26 2.4, 4.9 -1.38
SPRET/EiJ f 14.1 4.87   19 1.12 0.345 6.9, 25.8 0.94
SPRET/EiJ m 13.4 3.94   5 1.76 0.294 8.6, 19.1 0.93
SWR/J f 0.25 0.191   4 0.0957 0.766 0.1, 0.5 -2.42
SWR/J m 3.63 5.43   3 3.14 1.49 0.3, 9.9 -1.4
WSB/EiJ f 14.5 5.07   11 1.53 0.35 7.4, 22.0 1.03
WSB/EiJ m 13.0 2.39   6 0.976 0.184 11.2, 16.7 0.84


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.9389 1.2039 10.3032 5.5746
129S1/SvImJ m 6.6556 1.2039 9.0199 4.2913
A/J f 10.0133 1.3188 12.6033 7.4234
A/J m 11.1917 1.4744 14.0873 8.296
AKR/J f 5.5083 1.4744 8.404 2.6127
AKR/J m 7.6429 1.9305 11.4342 3.8515
BALB/cByJ f 13.01 1.6152 16.182 9.838
BALB/cByJ m 11.75 1.6152 14.922 8.578
BTBR T+ Itpr3tf/J f 15.8 1.3651 18.4809 13.1191
BTBR T+ Itpr3tf/J m 14.38 1.6152 17.552 11.208
BUB/BnJ f 5.6833 2.0852 9.7784 1.5882
BUB/BnJ m 5.76 2.2842 10.2459 1.2741
C3H/HeJ f 10.6538 1.4166 13.4359 7.8718
C3H/HeJ m 9.4636 1.54 12.4881 6.4392
C57BL/10J f 11.05 1.8058 14.5965 7.5035
C57BL/10J m 13.0286 1.9305 16.8199 9.2373
C57BL/6J f 17.26 1.3188 19.85 14.67
C57BL/6J m 15.3909 1.54 18.4153 12.3665
C57BLKS/J f 6.0857 1.9305 9.877 2.2944
C57BLKS/J m 4.725 2.5538 9.7404 0.0
C57BR/cdJ f 13.2417 1.4744 16.1373 10.346
C57BR/cdJ m 5.025 1.4744 7.9207 2.1293
C57L/J f 14.5333 2.0852 18.6284 10.4382
C57L/J m 10.9364 1.089 13.075 8.7978
C58/J f 7.13 1.6152 10.302 3.958
C58/J m 10.4429 1.3651 13.1237 7.762
CAST/EiJ f 13.1313 1.2769 15.639 10.6235
CAST/EiJ m 13.0556 1.7025 16.3992 9.7119
CBA/J f 10.8429 1.9305 14.6342 7.0515
CBA/J m 14.5125 1.8058 18.059 10.966
CZECHII/EiJ f 14.26 1.6152 17.432 11.088
CZECHII/EiJ m 5.575 2.5538 10.5904 0.5596
DBA/1J f 12.0 1.4744 14.8957 9.1043
DBA/1J m 11.14 1.6152 14.312 7.968
DBA/2J f 9.4176 1.2388 11.8505 6.9848
DBA/2J m 10.5067 1.3188 13.0966 7.9167
FVB/NJ f 11.5308 1.4166 14.3128 8.7487
FVB/NJ m 11.725 1.1421 13.968 9.482
I/LnJ f 7.4857 1.9305 11.277 3.6944
I/LnJ m 9.15 2.0852 13.2451 5.0549
JF1/MsJ f 11.3 1.6152 14.472 8.128
JF1/MsJ m 10.275 2.5538 15.2904 5.2596
LP/J f 7.4636 1.54 10.4881 4.4392
LP/J m 3.56 1.6152 6.732 0.388
MA/MyJ f 8.8 1.9305 12.5913 5.0087
MA/MyJ m 9.5 3.6116 16.5929 2.4071
MOLF/EiJ f 14.5 2.9489 20.2913 8.7087
MOLF/EiJ m 11.6 3.6116 18.6929 4.5071
NOD/ShiLtJ f 14.4667 2.9489 20.258 8.6753
NOD/ShiLtJ m 13.4 2.9489 19.1913 7.6087
NZB/BlNJ f 8.0 1.9305 11.7913 4.2087
NZB/BlNJ m 0.7857 1.9305 4.577 0.0
NZW/LacJ f 7.65 2.5538 12.6654 2.6346
NZW/LacJ m 4.2 2.5538 9.2154 0.0
PERA/EiJ f 16.4167 1.4744 19.3123 13.521
PERA/EiJ m 14.9636 1.54 17.9881 11.9392
PL/J f 4.375 2.5538 9.3904 0.0
PL/J m 6.45 3.6116 13.5429 0.0
PWK/PhJ f 11.42 2.2842 15.9059 6.9341
PWK/PhJ m 11.075 2.5538 16.0904 6.0596
RIIIS/J f 4.95 2.5538 9.9654 0.0
RIIIS/J m 8.175 1.4744 11.0707 5.2793
SEA/GnJ f 9.95 1.4744 12.8457 7.0543
SEA/GnJ m 10.2167 1.4744 13.1123 7.321
SJL/J f 3.95 1.3651 6.6309 1.2691
SJL/J m 2.14 1.6152 5.312 0.0
SM/J f 4.3 3.6116 11.3929 0.0
SM/J m 3.7333 2.0852 7.8284 0.0
SPRET/EiJ f 14.1368 1.1718 16.4381 11.8356
SPRET/EiJ m 13.38 2.2842 17.8659 8.8941
SWR/J f 0.25 2.5538 5.2654 0.0
SWR/J m 3.6333 2.9489 9.4247 0.0
WSB/EiJ f 14.4636 1.54 17.4881 11.4392
WSB/EiJ m 13.0167 2.0852 17.1118 8.9216


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 7.2972 0.8513 8.969 5.6254
A/J both 10.6025 0.9891 12.545 8.66
AKR/J both 6.5756 1.2146 8.9609 4.1903
BALB/cByJ both 12.38 1.1421 14.623 10.137
BTBR T+ Itpr3tf/J both 15.09 1.0574 17.1666 13.0134
BUB/BnJ both 5.7217 1.5464 8.7587 2.6847
C3H/HeJ both 10.0587 1.0462 12.1134 8.004
C57BL/10J both 12.0393 1.3217 14.635 9.4435
C57BL/6J both 16.3255 1.0138 18.3164 14.3345
C57BLKS/J both 5.4054 1.6007 8.549 2.2618
C57BR/cdJ both 9.1333 1.0426 11.1809 7.0858
C57L/J both 12.7348 1.1762 15.0448 10.4249
C58/J both 8.7864 1.0574 10.863 6.7098
CAST/EiJ both 13.0934 1.0641 15.1832 11.0036
CBA/J both 12.6777 1.3217 15.2734 10.0819
CZECHII/EiJ both 9.9175 1.5109 12.8847 6.9503
DBA/1J both 11.57 1.0935 13.7175 9.4225
DBA/2J both 9.9622 0.9047 11.7389 8.1855
FVB/NJ both 11.6279 0.9098 13.4147 9.8411
I/LnJ both 8.3179 1.4208 11.1082 5.5275
JF1/MsJ both 10.7875 1.5109 13.7547 7.8203
LP/J both 5.5118 1.1158 7.7032 3.3204
MA/MyJ both 9.15 2.0476 13.1713 5.1287
MOLF/EiJ both 13.05 2.3313 17.6285 8.4715
NOD/ShiLtJ both 13.9333 2.0852 18.0284 9.8382
NZB/BlNJ both 4.3929 1.3651 7.0737 1.712
NZW/LacJ both 5.925 1.8058 9.4715 2.3785
PERA/EiJ both 15.6902 1.066 17.7837 13.5966
PL/J both 5.4125 2.2117 9.756 1.069
PWK/PhJ both 11.2475 1.7132 14.612 7.883
RIIIS/J both 6.5625 1.4744 9.4582 3.6668
SEA/GnJ both 10.0833 1.0426 12.1309 8.0358
SJL/J both 3.045 1.0574 5.1216 0.9684
SM/J both 4.0167 2.0852 8.1118 0.0
SPRET/EiJ both 13.7584 1.2836 16.2793 11.2375
SWR/J both 1.9417 1.9505 5.7723 0.0
WSB/EiJ both 13.7402 1.2961 16.2856 11.1947




  GWAS USING LINEAR MIXED MODELS