Project measure / variable:   Wiltshire4   Bcells_Sel_A

ID, description, units MPD:52462   Bcells_Sel_A   B cells, percent viability   [%]  dose: 0.046 µM  
selumetinib study
Data set, strains Wiltshire4   inbred w/CC7   34 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - B cells, percent viability dose: 0.046 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested34 strains
Mean of the strain means98.8   %
Median of the strain means99.5   %
SD of the strain means± 13.3
Coefficient of variation (CV)0.135
Min–max range of strain means74.4   –   140   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 33 23152.6007 701.594 1.2721 0.1822
Residuals 99 54599.8154 551.5133


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 102.0 6.2   4 3.1 0.0608 97.9, 111.0 0.24
129X1/SvJ m 105.0 18.9   4 9.46 0.18 76.7, 116.0 0.46
A/J m 97.4 14.1   4 7.04 0.145 85.9, 118.0 -0.11
AKR/J m 102.0 10.0   4 5.02 0.0983 87.0, 107.0 0.24
BALB/cByJ m 99.2 1.64   4 0.821 0.0166 97.1, 101.0 0.03
BTBR T+ Itpr3tf/J m 95.3 24.2   4 12.1 0.254 59.7, 114.0 -0.26
BUB/BnJ m 102.0 8.31   4 4.15 0.0818 94.0, 109.0 0.24
C3H/HeJ m 92.0 4.74   4 2.37 0.0515 88.2, 98.9 -0.51
C57BL/6J m 99.5 4.93   4 2.46 0.0495 92.2, 103.0 0.05
C57BLKS/J m 75.9 22.5   4 11.2 0.296 48.2, 103.0 -1.72
C58/J m 91.4 1.03   2   0.725 0.0112 90.7, 92.1 -0.56
CBA/J m 89.9 31.7   4 15.9 0.353 55.8, 130.0 -0.67
CZECHII/EiJ m 81.0 24.8   4 12.4 0.307 60.7, 112.0 -1.33
DBA/2J m 115.0 63.9   4 31.9 0.558 47.7, 190.0 1.21
FVB/NJ m 99.3 10.4   4 5.19 0.104 88.3, 113.0 0.04
I/LnJ m 111.0 10.9   4 5.45 0.0985 94.9, 118.0 0.91
KK/HlJ m 94.1 11.1   4 5.56 0.118 78.1, 104.0 -0.35
LG/J m 74.4 63.2   4 31.6 0.849 -1.83
LP/J m 105.0 7.26   4 3.63 0.0692 98.1, 114.0 0.46
MA/MyJ m 101.0 7.19   4 3.59 0.0714 90.4, 106.0 0.16
NOD/ShiLtJ m 116.0 48.6   4 24.3 0.42 79.2, 186.0 1.29
NON/ShiLtJ m 104.0 18.3   4 9.14 0.175 87.7, 130.0 0.39
NZB/BlNJ m 98.4 7.04   4 3.52 0.0715 87.9, 103.0 -0.03
NZO/HlLtJ m 85.5 22.5   4 11.2 0.263 58.9, 105.0 -1.0
NZW/LacJ m 77.5 16.9   4 8.45 0.218 61.9, 101.0 -1.6
PERA/EiJ m 78.8 18.2   4 9.12 0.231 56.4, 101.0 -1.5
PL/J m 99.9 9.6   4 4.8 0.0961 88.2, 109.0 0.08
PWD/PhJ m 140.0 26.3   4 13.1 0.188 115.0, 168.0 3.09
PWK/PhJ m 103.0 7.02   4 3.51 0.0683 94.5, 111.0 0.31
RIIIS/J m 99.5 1.76   4 0.88 0.0177 97.1, 101.0 0.05
SEA/GnJ m 90.7 14.9   4 7.45 0.164 78.6, 112.0 -0.61
SJL/J m 119.0 20.6   4 10.3 0.173 94.2, 138.0 1.51
SM/J m 109.0 23.7   4 11.8 0.217 73.6, 123.0 0.76
WSB/EiJ m 106.0 18.4   3 10.6 0.173 89.7, 126.0 0.54


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 101.9675 11.7422 125.2665 78.6685
129X1/SvJ m 104.92 11.7422 128.219 81.621
A/J m 97.39 11.7422 120.689 74.091
AKR/J m 102.075 11.7422 125.374 78.776
BALB/cByJ m 99.185 11.7422 122.484 75.886
BTBR T+ Itpr3tf/J m 95.26 11.7422 118.559 71.961
BUB/BnJ m 101.5875 11.7422 124.8865 78.2885
C3H/HeJ m 92.045 11.7422 115.344 68.746
C57BL/6J m 99.505 11.7422 122.804 76.206
C57BLKS/J m 75.9225 11.7422 99.2215 52.6235
C58/J m 91.415 16.6059 124.3648 58.4652
CBA/J m 89.92 11.7422 113.219 66.621
CZECHII/EiJ m 81.0425 11.7422 104.3415 57.7435
DBA/2J m 114.585 11.7422 137.884 91.286
FVB/NJ m 99.305 11.7422 122.604 76.006
I/LnJ m 110.705 11.7422 134.004 87.406
KK/HlJ m 94.085 11.7422 117.384 70.786
LG/J m 74.4325 11.7422 97.7315 51.1335
LP/J m 104.93 11.7422 128.229 81.631
MA/MyJ m 100.5975 11.7422 123.8965 77.2985
NOD/ShiLtJ m 115.8175 11.7422 139.1165 92.5185
NON/ShiLtJ m 104.2075 11.7422 127.5065 80.9085
NZB/BlNJ m 98.44 11.7422 121.739 75.141
NZO/HlLtJ m 85.54 11.7422 108.839 62.241
NZW/LacJ m 77.4625 11.7422 100.7615 54.1635
PERA/EiJ m 78.84 11.7422 102.139 55.541
PL/J m 99.8625 11.7422 123.1615 76.5635
PWD/PhJ m 139.9025 11.7422 163.2015 116.6035
PWK/PhJ m 102.8725 11.7422 126.1715 79.5735
RIIIS/J m 99.5425 11.7422 122.8415 76.2435
SEA/GnJ m 90.7475 11.7422 114.0465 67.4485
SJL/J m 118.87 11.7422 142.169 95.571
SM/J m 109.0325 11.7422 132.3315 85.7335
WSB/EiJ m 106.11 13.5587 133.0134 79.2066




  GWAS USING LINEAR MIXED MODELS