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Project measure / variable:   Wiltshire4   Tcells_Dox_C

ID, description, units MPD:52430   Tcells_Dox_C   T cells, percent viability   [%]  dose: 1.235 µM  
doxorubicin study
Data set, strains Wiltshire4   inbred w/CC7   35 strains     sex: m     age: 10wks
Procedure immune cell quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Wiltshire4 - T cells, percent viability dose: 1.235 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means92.3   %
Median of the strain means93.0   %
SD of the strain means± 7.96
Coefficient of variation (CV)0.0862
Min–max range of strain means80.0   –   120   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 8457.2855 248.7437 10.5915 < 0.0001
Residuals 102 2395.4911 23.4852


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 105.0 4.32   4 2.16 0.041 100.0, 111.0 1.6
129X1/SvJ m 83.1 6.94   4 3.47 0.0836 77.2, 93.0 -1.16
A/J m 90.5 3.66   4 1.83 0.0404 88.1, 96.0 -0.23
AKR/J m 93.0 3.51   4 1.75 0.0377 90.1, 97.9 0.09
BALB/cByJ m 97.4 2.99   4 1.5 0.0307 94.8, 100.0 0.64
BTBR T+ Itpr3tf/J m 96.2 1.67   4 0.837 0.0174 94.9, 98.7 0.49
C3H/HeJ m 90.1 1.23   4 0.615 0.0137 88.4, 91.3 -0.28
C57BL/6J m 93.1 2.32   4 1.16 0.0249 90.9, 96.3 0.1
C57BLKS/J m 83.4 1.52   4 0.761 0.0182 81.7, 85.4 -1.12
C57BR/cdJ m 96.6 2.42   4 1.21 0.025 93.7, 98.7 0.54
C58/J m 95.7 1.42   2   1.0 0.0148 94.7, 96.7 0.43
CBA/J m 95.0 4.0   4 2.0 0.0421 91.1, 101.0 0.34
CZECHII/EiJ m 87.0 1.38   4 0.69 0.0159 85.3, 88.7 -0.67
DBA/2J m 93.7 3.28   4 1.64 0.035 89.9, 97.9 0.18
FVB/NJ m 94.6 0.982   4 0.491 0.0104 93.2, 95.4 0.29
I/LnJ m 94.8 3.37   4 1.68 0.0355 91.4, 98.9 0.31
KK/HlJ m 96.1 0.946   4 0.473 0.00985 95.2, 97.4 0.48
LG/J m 81.5 7.36   4 3.68 0.0904 72.6, 90.5 -1.36
LP/J m 90.4 2.89   4 1.44 0.032 86.1, 92.1 -0.24
MA/MyJ m 80.8 4.78   4 2.39 0.0591 77.5, 87.6 -1.45
NOD/ShiLtJ m 95.1 3.52   4 1.76 0.037 90.7, 99.3 0.35
NON/ShiLtJ m 82.6 6.71   4 3.36 0.0812 76.0, 89.9 -1.22
NZB/BlNJ m 92.4 2.45   4 1.22 0.0265 89.3, 95.2 0.01
NZO/HlLtJ m 87.3 5.05   4 2.53 0.0579 82.1, 94.2 -0.63
NZW/LacJ m 89.2 3.23   4 1.62 0.0363 86.5, 93.2 -0.39
PERA/EiJ m 94.9 8.61   4 4.3 0.0907 88.2, 107.0 0.33
PL/J m 87.0 6.53   4 3.27 0.0751 79.3, 93.5 -0.67
PWD/PhJ m 90.7 12.5   4 6.24 0.138 72.9, 102.0 -0.2
PWK/PhJ m 82.2 10.3   4 5.17 0.126 66.7, 88.2 -1.27
RIIIS/J m 101.0 5.59   4 2.79 0.0554 95.4, 109.0 1.09
SEA/GnJ m 96.4 1.19   4 0.597 0.0124 95.2, 97.4 0.52
SJL/J m 89.8 4.48   4 2.24 0.0499 83.6, 94.3 -0.31
SM/J m 80.0 4.01   4 2.01 0.0502 74.2, 83.2 -1.55
SWR/J m 120.0 0.993   4 0.497 0.00828 119.0, 121.0 3.48
WSB/EiJ m 104.0 2.08   3 1.2 0.02 102.0, 106.0 1.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 105.32 2.4231 110.1262 100.5138
129X1/SvJ m 83.0625 2.4231 87.8687 78.2563
A/J m 90.5325 2.4231 95.3387 85.7263
AKR/J m 92.9875 2.4231 97.7937 88.1813
BALB/cByJ m 97.415 2.4231 102.2212 92.6088
BTBR T+ Itpr3tf/J m 96.21 2.4231 101.0162 91.4038
C3H/HeJ m 90.105 2.4231 94.9112 85.2988
C57BL/6J m 93.05 2.4231 97.8562 88.2438
C57BLKS/J m 83.4 2.4231 88.2062 78.5938
C57BR/cdJ m 96.5775 2.4231 101.3837 91.7713
C58/J m 95.715 3.4267 102.5119 88.9181
CBA/J m 94.995 2.4231 99.8012 90.1888
CZECHII/EiJ m 86.995 2.4231 91.8012 82.1888
DBA/2J m 93.7375 2.4231 98.5437 88.9313
FVB/NJ m 94.5975 2.4231 99.4037 89.7913
I/LnJ m 94.7925 2.4231 99.5987 89.9863
KK/HlJ m 96.0825 2.4231 100.8887 91.2763
LG/J m 81.455 2.4231 86.2612 76.6488
LP/J m 90.39 2.4231 95.1962 85.5838
MA/MyJ m 80.82 2.4231 85.6262 76.0138
NOD/ShiLtJ m 95.085 2.4231 99.8912 90.2788
NON/ShiLtJ m 82.595 2.4231 87.4012 77.7888
NZB/BlNJ m 92.4375 2.4231 97.2437 87.6313
NZO/HlLtJ m 87.3075 2.4231 92.1137 82.5013
NZW/LacJ m 89.1575 2.4231 93.9637 84.3513
PERA/EiJ m 94.92 2.4231 99.7262 90.1138
PL/J m 87.0025 2.4231 91.8087 82.1963
PWD/PhJ m 90.7175 2.4231 95.5237 85.9113
PWK/PhJ m 82.1875 2.4231 86.9937 77.3813
RIIIS/J m 100.895 2.4231 105.7012 96.0888
SEA/GnJ m 96.3625 2.4231 101.1687 91.5563
SJL/J m 89.7625 2.4231 94.5687 84.9563
SM/J m 80.025 2.4231 84.8312 75.2188
SWR/J m 119.9 2.4231 124.7062 115.0938
WSB/EiJ m 104.09 2.7979 109.6397 98.5403




  GWAS USING LINEAR MIXED MODELS