Project measure / variable:   Wiltshire4   Bcells_Dox_C

ID, description, units MPD:52424   Bcells_Dox_C   B cells, percent viability   [%]  dose: 1.235 µM  
doxorubicin study
Data set, strains Wiltshire4   inbred w/CC7   35 strains     sex: m     age: 10wks
Procedure immune cell quantification
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  STRAIN COMPARISON PLOT
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Wiltshire4 - B cells, percent viability dose: 1.235 µM



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested35 strains
Mean of the strain means37.4   %
Median of the strain means32.6   %
SD of the strain means± 23.8
Coefficient of variation (CV)0.636
Min–max range of strain means6.69   –   95.6   %
Mean sample size per strain4.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 72961.7444 2145.9337 11.1463 < 0.0001
Residuals 102 19637.508 192.5246


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 72.1 26.2   4 13.1 0.363 50.0, 102.0 1.46
129X1/SvJ m 58.0 6.12   4 3.06 0.106 52.8, 65.2 0.87
A/J m 60.4 5.53   4 2.77 0.0917 53.1, 66.2 0.97
AKR/J m 40.3 7.52   4 3.76 0.186 31.5, 47.9 0.12
BALB/cByJ m 84.6 10.9   4 5.45 0.129 75.5, 98.0 1.99
BTBR T+ Itpr3tf/J m 26.3 9.21   4 4.61 0.35 17.0, 38.3 -0.47
C3H/HeJ m 19.6 5.07   4 2.54 0.259 14.3, 26.5 -0.75
C57BL/6J m 15.6 8.76   4 4.38 0.562 7.74, 28.1 -0.92
C57BLKS/J m 14.3 1.1   4 0.549 0.0767 13.5, 15.9 -0.97
C57BR/cdJ m 27.8 14.6   4 7.29 0.525 17.1, 49.0 -0.4
C58/J m 21.9 0.184   2   0.13 0.00839 21.8, 22.1 -0.65
CBA/J m 37.5 36.7   4 18.4 0.98 11.2, 91.8 0.0
CZECHII/EiJ m 17.4 1.59   4 0.797 0.0915 15.9, 19.2 -0.84
DBA/2J m 12.4 5.14   4 2.57 0.413 6.22, 18.3 -1.05
FVB/NJ m 41.5 13.0   4 6.49 0.313 27.9, 55.5 0.17
I/LnJ m 32.5 11.6   4 5.82 0.358 18.1, 45.2 -0.21
KK/HlJ m 79.7 2.89   4 1.45 0.0363 76.4, 82.7 1.78
LG/J m 28.0 12.9   4 6.44 0.46 18.4, 46.1 -0.4
LP/J m 16.7 10.6   4 5.29 0.634 8.0, 31.8 -0.87
MA/MyJ m 20.4 8.33   4 4.16 0.407 8.76, 27.3 -0.71
NOD/ShiLtJ m 30.6 6.1   4 3.05 0.199 24.0, 37.5 -0.29
NON/ShiLtJ m 33.8 6.8   4 3.4 0.201 27.8, 43.3 -0.15
NZB/BlNJ m 8.67 5.75   4 2.87 0.663 2.59, 15.2 -1.21
NZO/HlLtJ m 16.9 12.1   4 6.06 0.717 6.01, 34.2 -0.86
NZW/LacJ m 41.4 16.0   4 8.0 0.386 22.7, 61.6 0.17
PERA/EiJ m 40.0 23.1   4 11.6 0.578 18.8, 69.3 0.11
PL/J m 37.6 12.6   4 6.3 0.335 28.0, 55.1 0.01
PWD/PhJ m 36.8 15.6   4 7.81 0.424 17.3, 55.5 -0.02
PWK/PhJ m 79.4 8.96   4 4.48 0.113 66.5, 87.2 1.77
RIIIS/J m 32.6 16.5   4 8.27 0.508 14.6, 54.5 -0.2
SEA/GnJ m 73.4 14.4   4 7.18 0.196 51.9, 82.1 1.52
SJL/J m 6.69 7.62   4 3.81 1.14 2.05, 18.1 -1.29
SM/J m 12.4 5.81   4 2.91 0.47 3.74, 16.1 -1.05
SWR/J m 35.8 28.7   4 14.3 0.801 9.28, 76.4 -0.07
WSB/EiJ m 95.6 19.3   3 11.2 0.202 74.7, 113.0 2.45


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 72.1225 6.9377 85.8833 58.3617
129X1/SvJ m 58.01 6.9377 71.7708 44.2492
A/J m 60.355 6.9377 74.1158 46.5942
AKR/J m 40.3425 6.9377 54.1033 26.5817
BALB/cByJ m 84.605 6.9377 98.3658 70.8442
BTBR T+ Itpr3tf/J m 26.29 6.9377 40.0508 12.5292
C3H/HeJ m 19.5725 6.9377 33.3333 5.8117
C57BL/6J m 15.585 6.9377 29.3458 1.8242
C57BLKS/J m 14.3125 6.9377 28.0733 0.5517
C57BR/cdJ m 27.79 6.9377 41.5508 14.0292
C58/J m 21.92 9.8113 41.3807 2.4593
CBA/J m 37.495 6.9377 51.2558 23.7342
CZECHII/EiJ m 17.4325 6.9377 31.1933 3.6717
DBA/2J m 12.4275 6.9377 26.1883 0.0
FVB/NJ m 41.52 6.9377 55.2808 27.7592
I/LnJ m 32.47 6.9377 46.2308 18.7092
KK/HlJ m 79.695 6.9377 93.4558 65.9342
LG/J m 28.015 6.9377 41.7758 14.2542
LP/J m 16.68 6.9377 30.4408 2.9192
MA/MyJ m 20.435 6.9377 34.1958 6.6742
NOD/ShiLtJ m 30.645 6.9377 44.4058 16.8842
NON/ShiLtJ m 33.8025 6.9377 47.5633 20.0417
NZB/BlNJ m 8.665 6.9377 22.4258 0.0
NZO/HlLtJ m 16.91 6.9377 30.6708 3.1492
NZW/LacJ m 41.45 6.9377 55.2108 27.6892
PERA/EiJ m 39.9575 6.9377 53.7183 26.1967
PL/J m 37.5975 6.9377 51.3583 23.8367
PWD/PhJ m 36.835 6.9377 50.5958 23.0742
PWK/PhJ m 79.44 6.9377 93.2008 65.6792
RIIIS/J m 32.555 6.9377 46.3158 18.7942
SEA/GnJ m 73.36 6.9377 87.1208 59.5992
SJL/J m 6.69 6.9377 20.4508 0.0
SM/J m 12.37 6.9377 26.1308 0.0
SWR/J m 35.78 6.9377 49.5408 22.0192
WSB/EiJ m 95.64 8.0109 111.5296 79.7504




  GWAS USING LINEAR MIXED MODELS