Project measure / variable:   Rusyn6   Cyp4a10_liver_tce

ID, description, units MPD:51228   Cyp4a10_liver_tce   Cyp4a10, mRNA in liver, relative to control group   [ratio]  
trichloroethylene study
Data set, strains Rusyn6   inbred   7 strains     sex: m     age: 6-7wks
Procedure RNA expression profiling
Ontology mappings

  STRAIN COMPARISON PLOT
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Rusyn6 - Cyp4a10, mRNA in liver, relative to control group

NZW/LacJNOD/ShiLtJA/JC57BL/6JBTBR T<+> Itpr3<tf>/J129S1/SvImJCAST/EiJ ratio -20020406080100120140160femalemale


  MEASURE SUMMARY
Measure Summary Male
Number of strains tested7 strains
Mean of the strain means32.5   ratio
Median of the strain means10.8   ratio
SD of the strain means± 49.4
Coefficient of variation (CV)1.52
Min–max range of strain means2.70   –   141   ratio
Mean sample size per strain2.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 6 43224.107 7204.0178 51.7654 < 0.0001
Residuals 13 1809.165 139.1665


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Strain
Sex
Mean
SD
N mice
SEM
CV
Min, Max
Z score
129S1/SvImJ m 9.15 0.636   2   0.45 0.0696 8.7, 9.6 -0.47
A/J m 12.2 5.98   3 3.45 0.49 5.5, 17.0 -0.41
BTBR T+ Itpr3tf/J m 10.1 1.16   3 0.669 0.114 8.8, 10.9 -0.45
C57BL/6J m 10.8 9.67   3 5.58 0.895 4.2, 21.9 -0.44
CAST/EiJ m 2.7 2.8   3 1.62 1.04 0.7, 5.9 -0.6
NOD/ShiLtJ m 41.5 20.0   3 11.6 0.482 19.9, 59.4 0.18
NZW/LacJ m 141.0 19.1   3 11.0 0.136 123.0, 161.0 2.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 9.15 8.3417 27.1711 0.0
A/J m 12.2 6.8109 26.9141 0.0
BTBR T+ Itpr3tf/J m 10.1333 6.8109 24.8475 0.0
C57BL/6J m 10.8 6.8109 25.5141 0.0
CAST/EiJ m 2.7 6.8109 17.4141 0.0
NOD/ShiLtJ m 41.5333 6.8109 56.2475 26.8192
NZW/LacJ m 140.6667 6.8109 155.3808 125.9525




  GWAS USING LINEAR MIXED MODELS

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