Project measure / variable:   HMDPpheno8   cholesterol

ID, description, units MPD:50387   cholesterol   liver cholesterol (16h fast), relative abundance    
Data set, strains HMDPpheno8   HMDP   106 strains     sex: m     age: 16wks
Procedure metabolite quantification
Ontology mappings


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  STRAIN COMPARISON PLOT
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HMDPpheno8 - liver cholesterol (16h fast), relative abundance



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested106 strains
Mean of the strain means13274408   None
Median of the strain means13145704   None
SD of the strain means± 2158388
Coefficient of variation (CV)0.163
Min–max range of strain means8455217   –   19791924   None
Mean sample size per strain1.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 101705846255217.0 4843135535962.73 2.4847 0.0088
Residuals 34 66272601175888.1 1949194152232.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129X1/SvJ m 11317790.0 0.0   1   0.0 0.0 11317790.0, 11317790.0 -0.91
A/J m 12921856.0 182682.0   2   129176.0 0.0141 12792680.0, 13051032.0 -0.16
AKR/J m 13616331.0 0.0   1   0.0 0.0 13616331.0, 13616331.0 0.16
AXB10/PgnJ m 10941655.0 0.0   1   0.0 0.0 10941655.0, 10941655.0 -1.08
AXB12/PgnJ m 8455217.0 0.0   1   0.0 0.0 8455217.0, 8455217.0 -2.23
AXB13/PgnJ m 11891775.0 0.0   1   0.0 0.0 11891775.0, 11891775.0 -0.64
AXB15/PgnJ m 13051416.0 0.0   1   0.0 0.0 13051416.0, 13051416.0 -0.1
AXB19a/PgnJ m 15767576.0 0.0   1   0.0 0.0 15767576.0, 15767576.0 1.16
AXB19b/PgnJ m 18022685.0 1334592.0   2   943699.0 0.0741 17078986.0, 18966384.0 2.2
AXB19/PgnJ m 15628221.0 0.0   1   0.0 0.0 15628221.0, 15628221.0 1.09
AXB1/PgnJ m 18712218.0 0.0   1   0.0 0.0 18712218.0, 18712218.0 2.52
AXB23/PgnJ m 13838890.0 0.0   1   0.0 0.0 13838890.0, 13838890.0 0.26
AXB24/PgnJ m 11775080.0 2302024.0   2   1627776.0 0.195 10147303.0, 13402856.0 -0.69
AXB2/PgnJ m 10724854.0 0.0   1   0.0 0.0 10724854.0, 10724854.0 -1.18
AXB4/PgnJ m 13182719.0 0.0   1   0.0 0.0 13182719.0, 13182719.0 -0.04
AXB5/PgnJ m 9391448.0 0.0   1   0.0 0.0 9391448.0, 9391448.0 -1.8
AXB6/PgnJ m 15047019.0 0.0   1   0.0 0.0 15047019.0, 15047019.0 0.82
AXB8/PgnJ m 10984972.0 0.0   1   0.0 0.0 10984972.0, 10984972.0 -1.06
BALB/cJ m 12893730.0 614065.0   3 354531.0 0.0476 12292355.0, 13519744.0 -0.18
BTBR T+ Itpr3tf/J m 12397460.0 0.0   1   0.0 0.0 12397460.0, 12397460.0 -0.41
BUB/BnJ m 14369051.0 0.0   1   0.0 0.0 14369051.0, 14369051.0 0.51
BXA11/PgnJ m 12200252.0 0.0   1   0.0 0.0 12200252.0, 12200252.0 -0.5
BXA12/PgnJ m 9185125.0 0.0   1   0.0 0.0 9185125.0, 9185125.0 -1.89
BXA13/PgnJ m 15735315.0 0.0   1   0.0 0.0 15735315.0, 15735315.0 1.14
BXA14/PgnJ m 12760364.0 0.0   1   0.0 0.0 12760364.0, 12760364.0 -0.24
BXA16/PgnJ m 12767372.0 684948.0   2   484331.0 0.0536 12283041.0, 13251704.0 -0.23
BXA1/PgnJ m 13864562.0 0.0   1   0.0 0.0 13864562.0, 13864562.0 0.27
BXA24/PgnJ m 14257475.0 0.0   1   0.0 0.0 14257475.0, 14257475.0 0.46
BXA25/PgnJ m 10312410.0 0.0   1   0.0 0.0 10312410.0, 10312410.0 -1.37
BXA26/PgnJ m 10834038.0 0.0   1   0.0 0.0 10834038.0, 10834038.0 -1.13
BXA2/PgnJ m 12588579.0 0.0   1   0.0 0.0 12588579.0, 12588579.0 -0.32
BXA4/PgnJ m 10991705.0 0.0   1   0.0 0.0 10991705.0, 10991705.0 -1.06
BXA7/PgnJ m 12736297.0 0.0   1   0.0 0.0 12736297.0, 12736297.0 -0.25
BXA8/PgnJ m 9802426.0 0.0   1   0.0 0.0 9802426.0, 9802426.0 -1.61
BXD11/TyJ m 12167507.0 0.0   1   0.0 0.0 12167507.0, 12167507.0 -0.51
BXD12/TyJ m 16830158.0 0.0   1   0.0 0.0 16830158.0, 16830158.0 1.65
BXD13/TyJ m 11908871.0 0.0   1   0.0 0.0 11908871.0, 11908871.0 -0.63
BXD14/TyJ m 14373169.0 0.0   1   0.0 0.0 14373169.0, 14373169.0 0.51
BXD15/TyJ m 13327836.0 0.0   1   0.0 0.0 13327836.0, 13327836.0 0.02
BXD18/TyJ m 13145512.0 0.0   1   0.0 0.0 13145512.0, 13145512.0 -0.06
BXD19/TyJ m 12362678.0 830244.0   2   587072.0 0.0672 11775606.0, 12949749.0 -0.42
BXD1/TyJ m 12408498.0 0.0   1   0.0 0.0 12408498.0, 12408498.0 -0.4
BXD20/TyJ m 15042374.0 0.0   1   0.0 0.0 15042374.0, 15042374.0 0.82
BXD21/TyJ m 9424265.0 0.0   1   0.0 0.0 9424265.0, 9424265.0 -1.78
BXD22/TyJ m 14144596.0 0.0   1   0.0 0.0 14144596.0, 14144596.0 0.4
BXD24/TyJ m 10664074.0 0.0   1   0.0 0.0 10664074.0, 10664074.0 -1.21
BXD24/TyJ-Cep290rd16/J m 11566861.0 0.0   1   0.0 0.0 11566861.0, 11566861.0 -0.79
BXD28/TyJ m 12645461.0 1735407.0   2   1227118.0 0.137 11418343.0, 13872579.0 -0.29
BXD29-Tlr4lps-2J/J m 14933011.0 0.0   1   0.0 0.0 14933011.0, 14933011.0 0.77
BXD2/TyJ m 17018288.0 0.0   1   0.0 0.0 17018288.0, 17018288.0 1.73
BXD32/TyJ m 11426087.0 0.0   1   0.0 0.0 11426087.0, 11426087.0 -0.86
BXD33/TyJ m 16544806.0 0.0   1   0.0 0.0 16544806.0, 16544806.0 1.52
BXD34/TyJ m 12185299.0 0.0   1   0.0 0.0 12185299.0, 12185299.0 -0.5
BXD36/TyJ m 11573526.0 0.0   1   0.0 0.0 11573526.0, 11573526.0 -0.79
BXD38/TyJ m 8905954.0 0.0   1   0.0 0.0 8905954.0, 8905954.0 -2.02
BXD39/TyJ m 13014208.0 0.0   1   0.0 0.0 13014208.0, 13014208.0 -0.12
BXD40/TyJ m 13983799.0 0.0   1   0.0 0.0 13983799.0, 13983799.0 0.33
BXD42/TyJ m 13255105.0 0.0   1   0.0 0.0 13255105.0, 13255105.0 -0.01
BXD5/TyJ m 13145896.0 0.0   1   0.0 0.0 13145896.0, 13145896.0 -0.06
BXD6/TyJ m 14414963.0 0.0   1   0.0 0.0 14414963.0, 14414963.0 0.53
BXD8/TyJ m 9495834.0 0.0   1   0.0 0.0 9495834.0, 9495834.0 -1.75
BXD9/TyJ m 12238930.0 0.0   1   0.0 0.0 12238930.0, 12238930.0 -0.48
BXH10/TyJ m 10401631.0 0.0   1   0.0 0.0 10401631.0, 10401631.0 -1.33
BXH19/TyJ m 14420806.0 0.0   1   0.0 0.0 14420806.0, 14420806.0 0.53
BXH20/KccJ m 15194984.0 0.0   1   0.0 0.0 15194984.0, 15194984.0 0.89
BXH22/KccJ m 15542988.0 0.0   1   0.0 0.0 15542988.0, 15542988.0 1.05
BXH2/TyJ m 13521324.0 0.0   1   0.0 0.0 13521324.0, 13521324.0 0.11
BXH4/TyJ m 13756535.0 1346535.0   2   952144.0 0.0979 12804391.0, 14708679.0 0.22
BXH6/TyJ m 14662679.0 0.0   1   0.0 0.0 14662679.0, 14662679.0 0.64
BXH7/TyJ m 14682615.0 0.0   1   0.0 0.0 14682615.0, 14682615.0 0.65
BXH8/TyJ m 16346040.0 0.0   1   0.0 0.0 16346040.0, 16346040.0 1.42
BXH9/TyJ m 14582746.0 0.0   1   0.0 0.0 14582746.0, 14582746.0 0.61
C3H/HeJ m 14333182.0 3119.0   2   2206.0 0.000218 14330976.0, 14335387.0 0.49
C57BL/6J m 13785639.0 1491242.0   5 666904.0 0.108 12374545.0, 15700899.0 0.24
C57L/J m 10116415.0 0.0   1   0.0 0.0 10116415.0, 10116415.0 -1.46
C58/J m 19791924.0 0.0   1   0.0 0.0 19791924.0, 19791924.0 3.02
CAST/EiJ m 15879049.0 0.0   1   0.0 0.0 15879049.0, 15879049.0 1.21
CBA/J m 11779896.0 0.0   1   0.0 0.0 11779896.0, 11779896.0 -0.69
CE/J m 12162687.0 0.0   1   0.0 0.0 12162687.0, 12162687.0 -0.52
CXB11/HiAJ m 14283542.0 4022325.0   2   2844213.0 0.282 11439329.0, 17127756.0 0.47
CXB12/HiAJ m 11355844.0 823879.0   2   582570.0 0.0726 10773273.0, 11938414.0 -0.89
CXB13/HiAJ m 14849637.0 1850553.0   3 1068417.0 0.125 12714526.0, 15991495.0 0.73
CXB1/ByJ m 14200824.0 1019718.0   3 588735.0 0.0718 13102230.0, 15117060.0 0.43
CXB2/ByJ m 13135429.0 1150798.0   3 664414.0 0.0876 11851926.0, 14075178.0 -0.06
CXB3/ByJ m 11881494.0 264744.0   2   187202.0 0.0223 11694292.0, 12068697.0 -0.65
CXB4/ByJ m 11692130.0 358908.0   2   253786.0 0.0307 11438344.0, 11945916.0 -0.73
CXB6/ByJ m 11726364.0 621653.0   3 358911.0 0.053 11146459.0, 12382697.0 -0.72
CXB7/ByJ m 12663355.0 30492.0   2   21561.0 0.00241 12641794.0, 12684916.0 -0.28
CXB8/HiAJ m 14465522.0 498868.0   3 288022.0 0.0345 13940868.0, 14933818.0 0.55
CXB9/HiAJ m 12637113.0 1752559.0   3 1011840.0 0.139 10789444.0, 14275827.0 -0.3
DBA/2J m 12445054.0 1578761.0   4 789380.0 0.127 10904675.0, 14478914.0 -0.38
FVB/NJ m 16529480.0 0.0   1   0.0 0.0 16529480.0, 16529480.0 1.51
I/LnJ m 16338330.0 0.0   1   0.0 0.0 16338330.0, 16338330.0 1.42
KK/HlJ m 13522052.0 0.0   1   0.0 0.0 13522052.0, 13522052.0 0.11
LG/J m 13753585.0 0.0   1   0.0 0.0 13753585.0, 13753585.0 0.22
LP/J m 14144599.0 0.0   1   0.0 0.0 14144599.0, 14144599.0 0.4
MA/MyJ m 13883700.0 0.0   1   0.0 0.0 13883700.0, 13883700.0 0.28
NOD/ShiLtJ m 12218269.0 0.0   1   0.0 0.0 12218269.0, 12218269.0 -0.49
NON/ShiLtJ m 14393407.0 0.0   1   0.0 0.0 14393407.0, 14393407.0 0.52
NZW/LacJ m 10941473.0 0.0   1   0.0 0.0 10941473.0, 10941473.0 -1.08
PL/J m 15227980.0 0.0   1   0.0 0.0 15227980.0, 15227980.0 0.91
RIIIS/J m 12414108.0 0.0   1   0.0 0.0 12414108.0, 12414108.0 -0.4
SEA/GnJ m 15052950.0 0.0   1   0.0 0.0 15052950.0, 15052950.0 0.82
SJL/J m 13519788.0 0.0   1   0.0 0.0 13519788.0, 13519788.0 0.11
SM/J m 16461713.0 0.0   1   0.0 0.0 16461713.0, 16461713.0 1.48
SWR/J m 17272926.0 0.0   1   0.0 0.0 17272926.0, 17272926.0 1.85


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J m 12921856.0 987216.8334 14928121.9891 10915590.0109
AXB19b/PgnJ m 18022685.0 987216.8334 20028950.9891 16016419.0109
AXB24/PgnJ m 11775079.5 987216.8334 13781345.4891 9768813.5109
BALB/cJ m 12893730.3333 806059.1691 14531839.6539 11255621.0128
BXA16/PgnJ m 12767372.5 987216.8334 14773638.4891 10761106.5109
BXD19/TyJ m 12362677.5 987216.8334 14368943.4891 10356411.5109
BXD28/TyJ m 12645461.0 987216.8334 14651726.9891 10639195.0109
BXH4/TyJ m 13756535.0 987216.8334 15762800.9891 11750269.0109
C3H/HeJ m 14333181.5 987216.8334 16339447.4891 12326915.5109
C57BL/6J m 13785638.8 624370.7476 15054512.8236 12516764.7764
CXB11/HiAJ m 14283542.5 987216.8334 16289808.4891 12277276.5109
CXB12/HiAJ m 11355843.5 987216.8334 13362109.4891 9349577.5109
CXB13/HiAJ m 14849637.0 806059.1691 16487746.3206 13211527.6794
CXB1/ByJ m 14200824.0 806059.1691 15838933.3206 12562714.6794
CXB2/ByJ m 13135428.6667 806059.1691 14773537.9872 11497319.3461
CXB3/ByJ m 11881494.5 987216.8334 13887760.4891 9875228.5109
CXB4/ByJ m 11692130.0 987216.8334 13698395.9891 9685864.0109
CXB6/ByJ m 11726364.0 806059.1691 13364473.3206 10088254.6794
CXB7/ByJ m 12663355.0 987216.8334 14669620.9891 10657089.0109
CXB8/HiAJ m 14465521.6667 806059.1691 16103630.9872 12827412.3461
CXB9/HiAJ m 12637112.6667 806059.1691 14275221.9872 10999003.3461
DBA/2J m 12445054.5 698067.7174 13863698.7858 11026410.2142




  GWAS USING LINEAR MIXED MODELS