Project measure / variable:   Chesler2   BUN

ID, description, units MPD:43409   BUN   blood urea nitrogen (BUN)   [mg/dL]  
Data set, strains Chesler2   CC diallel w/par   48 strains     sex: both     age: 7-15wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Chesler2 - blood urea nitrogen (BUN)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — 12.0 18.5 15.5 — — 25.0 —
A ♀ — — 18.0 — — 15.0 — —
B6 ♀ 16.5 18.0 19.4 — 15.0 15.0 22.0 —
CAST ♀ — 20.0 19.0 26.0 — 12.2 20.8 23.5
NOD ♀ — 14.0 14.0 — 17.0 14.5 — —
NZO ♀ 13.0 16.0 — — — — — 13.3
PWK ♀ 18.0 30.0 — — 23.0 — — —
WSB ♀ 16.0 19.0 21.0 — 17.0 16.0 22.0 14.0

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — 23.0 20.0 — 19.5 17.5 — —
A ♀ — 20.0 20.0 — 20.4 — 27.0 20.0
B6 ♀ — 23.0 24.5 — 20.5 19.0 — —
CAST ♀ 23.0 25.5 22.3 23.0 30.0 20.0 24.7 —
NOD ♀ — — — — 13.0 17.5 — —
NZO ♀ — — 14.0 — 14.0 16.0 — —
PWK ♀ — 19.0 — — — — 53.0 —
WSB ♀ — 21.0 19.7 20.7 16.0 18.8 — 16.5

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested35 strains33 strains
Mean of the strain means18.0   mg/dL 21.3   mg/dL
Median of the strain means17.0   mg/dL 20.0   mg/dL
SD of the strain means± 4.19 ± 6.80
Coefficient of variation (CV)0.233 0.320
Min–max range of strain means12.0   –   30.0   mg/dL 13.0   –   53.0   mg/dL
Mean sample size per strain1.8   mice 2.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 294.8299 294.8299 25.9946 < 0.0001
strain 7 645.3412 92.1916 8.1284 < 0.0001
sex:strain 7 119.7444 17.1063 1.5082 0.1771
Residuals 77 873.3318 11.342


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129SAF1 f 12.0 0.0   1   0.0 0.0 12.0, 12.0 -1.43
129SAF1 m 23.0 4.24   2   3.0 0.184 20.0, 26.0 0.25
129SB6F1 f 18.5 3.54   2   2.5 0.191 16.0, 21.0 0.12
129SB6F1 m 20.0 1.41   2   1.0 0.0707 19.0, 21.0 -0.19
129SCASTF1 f 15.5 2.12   2   1.5 0.137 14.0, 17.0 -0.59
129SNODF1 m 19.5 0.707   2   0.5 0.0363 19.0, 20.0 -0.26
129SNZOF1 m 17.5 2.12   2   1.5 0.121 16.0, 19.0 -0.55
129SPWKF1 f 25.0 0.0   1   0.0 0.0 25.0, 25.0 1.68
AB6F1 f 18.0 0.0   1   0.0 0.0 18.0, 18.0 0.01
AB6F1 m 20.0 4.76   4 2.38 0.238 15.0, 25.0 -0.19
A/J m 20.0 2.16   4 1.08 0.108 17.0, 22.0 -0.19
ANODF1 m 20.4 1.62   7 0.612 0.0792 18.0, 23.0 -0.13
ANZOF1 f 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.71
APWKF1 m 27.0 0.0   1   0.0 0.0 27.0, 27.0 0.84
AWSBF1 m 20.0 0.0   1   0.0 0.0 20.0, 20.0 -0.19
B6129SF1/J f 16.5 0.707   2   0.5 0.0429 16.0, 17.0 -0.35
B6AF1/J f 18.0 0.0   1   0.0 0.0 18.0, 18.0 0.01
B6AF1/J m 23.0 0.0   1   0.0 0.0 23.0, 23.0 0.25
B6NODF1 f 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.71
B6NODF1 m 20.5 2.12   2   1.5 0.103 19.0, 22.0 -0.11
B6NZOF1 f 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.71
B6NZOF1 m 19.0 0.0   1   0.0 0.0 19.0, 19.0 -0.33
B6PWKF1 f 22.0 0.0   1   0.0 0.0 22.0, 22.0 0.96
C57BL/6J f 19.4 2.87   15 0.742 0.148 15.0, 24.0 0.34
C57BL/6J m 24.5 3.66   33 0.637 0.15 18.0, 32.0 0.47
CAST129SF1 m 23.0 4.24   2   3.0 0.184 20.0, 26.0 0.25
CASTAF1 f 20.0 0.0   1   0.0 0.0 20.0, 20.0 0.48
CASTAF1 m 25.5 2.12   2   1.5 0.0832 24.0, 27.0 0.62
CASTB6F1 f 19.0 0.0   1   0.0 0.0 19.0, 19.0 0.24
CASTB6F1 m 22.3 1.53   3 0.882 0.0684 21.0, 24.0 0.15
CAST/EiJ f 26.0 5.83   5 2.61 0.224 21.0, 36.0 1.92
CAST/EiJ m 23.0 2.83   2   2.0 0.123 21.0, 25.0 0.25
CASTNODF1 m 30.0 0.0   1   0.0 0.0 30.0, 30.0 1.28
CASTNZOF1 f 12.2 1.5   4 0.75 0.122 10.0, 13.0 -1.38
CASTNZOF1 m 20.0 0.0   1   0.0 0.0 20.0, 20.0 -0.19
CASTPWKF1 f 20.8 1.92   5 0.86 0.0925 18.0, 23.0 0.67
CASTPWKF1 m 24.7 3.93   6 1.61 0.159 19.0, 29.0 0.5
CASTWSBF1 f 23.5 4.95   2   3.5 0.211 20.0, 27.0 1.32
NODAF1 f 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.95
NODB6F1 f 14.0 2.65   3 1.53 0.189 12.0, 17.0 -0.95
NODNZOF1 f 14.5 0.707   2   0.5 0.0488 14.0, 15.0 -0.83
NODNZOF1 m 17.5 0.707   2   0.5 0.0404 17.0, 18.0 -0.55
NOD/ShiLtJ f 17.0 0.0   1   0.0 0.0 17.0, 17.0 -0.23
NOD/ShiLtJ m 13.0 0.0   1   0.0 0.0 13.0, 13.0 -1.22
NZO129SF1 f 13.0 0.0   1   0.0 0.0 13.0, 13.0 -1.19
NZOAF1 f 16.0 0.0   1   0.0 0.0 16.0, 16.0 -0.47
NZOB6F1 m 14.0 0.0   1   0.0 0.0 14.0, 14.0 -1.07
NZO/HlLtJ m 16.0 0.0   1   0.0 0.0 16.0, 16.0 -0.78
NZONODF1 m 14.0 0.0   1   0.0 0.0 14.0, 14.0 -1.07
NZOWSBF1 f 13.3 0.577   3 0.333 0.0433 13.0, 14.0 -1.12
PWK129SF1 f 18.0 0.0   1   0.0 0.0 18.0, 18.0 0.01
PWKAF1 f 30.0 0.0   1   0.0 0.0 30.0, 30.0 2.87
PWKAF1 m 19.0 0.0   1   0.0 0.0 19.0, 19.0 -0.33
PWKNODF1 f 23.0 0.0   1   0.0 0.0 23.0, 23.0 1.2
PWK/PhJ m 53.0 36.8   2   26.0 0.694 27.0, 79.0 4.66
WSB129SF1 f 16.0 0.0   1   0.0 0.0 16.0, 16.0 -0.47
WSBAF1 f 19.0 0.0   1   0.0 0.0 19.0, 19.0 0.24
WSBAF1 m 21.0 0.0   1   0.0 0.0 21.0, 21.0 -0.04
WSBB6F1 f 21.0 1.41   2   1.0 0.0673 20.0, 22.0 0.72
WSBB6F1 m 19.7 1.53   3 0.882 0.0777 18.0, 21.0 -0.23
WSBCASTF1 m 20.7 2.52   3 1.45 0.122 18.0, 23.0 -0.08
WSB/EiJ f 14.0 2.83   2   2.0 0.202 12.0, 16.0 -0.95
WSB/EiJ m 16.5 0.707   2   0.5 0.0429 16.0, 17.0 -0.7
WSBNODF1 f 17.0 0.0   1   0.0 0.0 17.0, 17.0 -0.23
WSBNODF1 m 16.0 0.0   2   0.0 0.0 16.0, 16.0 -0.78
WSBNZOF1 f 16.0 2.68   6 1.1 0.168 12.0, 20.0 -0.47
WSBNZOF1 m 18.8 2.99   4 1.49 0.159 16.0, 23.0 -0.36
WSBPWKF1 f 22.0 4.24   2   3.0 0.193 19.0, 25.0 0.96


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SB6F1 f 18.5 2.3814 23.2419 13.7581
129SB6F1 m 20.0 2.3814 24.7419 15.2581
C57BL/6J f 19.4 0.8696 21.1315 17.6685
C57BL/6J m 24.4545 0.5863 25.6219 23.2872
CAST/EiJ f 26.0 1.5061 28.9991 23.0009
CAST/EiJ m 23.0 2.3814 27.7419 18.2581
CASTPWKF1 f 20.8 1.5061 23.7991 17.8009
CASTPWKF1 m 24.6667 1.3749 27.4044 21.9289
NODNZOF1 f 14.5 2.3814 19.2419 9.7581
NODNZOF1 m 17.5 2.3814 22.2419 12.7581
WSBB6F1 f 21.0 2.3814 25.7419 16.2581
WSBB6F1 m 19.6667 1.9444 23.5384 15.7949
WSB/EiJ f 14.0 2.3814 18.7419 9.2581
WSB/EiJ m 16.5 2.3814 21.2419 11.7581
WSBNZOF1 f 16.0 1.3749 18.7378 13.2622
WSBNZOF1 m 18.75 1.6839 22.1031 15.3969


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SB6F1 both 19.25 1.6839 22.6031 15.8969
C57BL/6J both 21.9273 0.5244 22.9714 20.8831
CAST/EiJ both 24.5 1.4088 27.3054 21.6946
CASTPWKF1 both 22.7333 1.0196 24.7637 20.703
NODNZOF1 both 16.0 1.6839 19.3531 12.6469
WSBB6F1 both 20.3333 1.5372 23.3942 17.2724
WSB/EiJ both 15.25 1.6839 18.6031 11.8969
WSBNZOF1 both 17.375 1.0869 19.5394 15.2106




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA