Project measure / variable:   Chesler2   sodium

ID, description, units MPD:43401   sodium   sodium (blood Na)   [mmol/L]  
Data set, strains Chesler2   CC diallel w/par   48 strains     sex: both     age: 7-15wks
Procedure metabolic panel
Ontology mappings

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  STRAIN COMPARISON PLOT
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Chesler2 - sodium (blood Na)



  8-WAY DIALLEL CROSS VIEW
Female animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — 148 146 146 — — 146 —
A ♀ — — 146 — — 147 — —
B6 ♀ 144 147 147 — 146 144 148 —
CAST ♀ — 147 145 148 — 146 146 148
NOD ♀ — 145 147 — 143 146 — —
NZO ♀ 145 145 — — — — — 145
PWK ♀ 146 146 — — 147 — — —
WSB ♀ 145 148 146 — 146 145 148 150

Male animals
129S ♂ A ♂ B6 ♂ CAST ♂ NOD ♂ NZO ♂ PWK ♂ WSB ♂
129S ♀ — 148 146 — 145 144 — —
A ♀ — 147 146 — 147 — 150 149
B6 ♀ — 146 144 — 146 145 — —
CAST ♀ 147 148 149 147 149 148 149 —
NOD ♀ — — — — 145 146 — —
NZO ♀ — — 140 — 145 142 — —
PWK ♀ — 148 — — — — 148 —
WSB ♀ — 151 148 149 148 146 — 152

Cell coloring is based on strain mean Z-scores.     High-end         Mid         Low-end           Mouse over the cells to see additional info.


  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested35 strains33 strains
Mean of the strain means146   mmol/L 147   mmol/L
Median of the strain means146   mmol/L 147   mmol/L
SD of the strain means± 1.42 ± 2.44
Coefficient of variation (CV)0.00968 0.0166
Min–max range of strain means143   –   150   mmol/L 140   –   152   mmol/L
Mean sample size per strain1.8   mice 2.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 25.5043 25.5043 10.5256 0.0017
strain 7 164.74 23.5343 9.7125 < 0.0001
sex:strain 7 94.2967 13.471 5.5594 < 0.0001
Residuals 77 186.5773 2.4231


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129SAF1 f 148.0 0.0   1   0.0 0.0 148.0, 148.0 1.25
129SAF1 m 148.0 0.707   2   0.5 0.00479 147.0, 148.0 0.45
129SB6F1 f 146.0 1.41   2   1.0 0.00969 145.0, 147.0 -0.16
129SB6F1 m 146.0 0.707   2   0.5 0.00483 146.0, 147.0 -0.37
129SCASTF1 f 146.0 0.707   2   0.5 0.00483 146.0, 147.0 -0.16
129SNODF1 m 145.0 1.41   2   1.0 0.00975 144.0, 146.0 -0.78
129SNZOF1 m 144.0 0.0   2   0.0 0.0 144.0, 144.0 -1.19
129SPWKF1 f 146.0 0.0   1   0.0 0.0 146.0, 146.0 -0.16
AB6F1 f 146.0 0.0   1   0.0 0.0 146.0, 146.0 -0.16
AB6F1 m 146.0 1.41   4 0.707 0.00969 145.0, 148.0 -0.37
A/J m 147.0 1.71   4 0.854 0.0116 145.0, 149.0 0.04
ANODF1 m 147.0 0.9   7 0.34 0.00613 146.0, 148.0 0.04
ANZOF1 f 147.0 0.0   1   0.0 0.0 147.0, 147.0 0.54
APWKF1 m 150.0 0.0   1   0.0 0.0 150.0, 150.0 1.27
AWSBF1 m 149.0 0.0   1   0.0 0.0 149.0, 149.0 0.86
B6129SF1/J f 144.0 0.707   2   0.5 0.00489 144.0, 145.0 -1.57
B6AF1/J f 147.0 0.0   1   0.0 0.0 147.0, 147.0 0.54
B6AF1/J m 146.0 0.0   1   0.0 0.0 146.0, 146.0 -0.37
B6NODF1 f 146.0 0.0   1   0.0 0.0 146.0, 146.0 -0.16
B6NODF1 m 146.0 0.707   2   0.5 0.00486 145.0, 146.0 -0.37
B6NZOF1 f 144.0 0.0   1   0.0 0.0 144.0, 144.0 -1.57
B6NZOF1 m 145.0 0.0   1   0.0 0.0 145.0, 145.0 -0.78
B6PWKF1 f 148.0 0.0   1   0.0 0.0 148.0, 148.0 1.25
C57BL/6J f 147.0 1.39   15 0.358 0.00943 145.0, 150.0 0.54
C57BL/6J m 144.0 1.46   33 0.254 0.0101 141.0, 147.0 -1.19
CAST129SF1 m 147.0 0.0   2   0.0 0.0 147.0, 147.0 0.04
CASTAF1 f 147.0 0.0   1   0.0 0.0 147.0, 147.0 0.54
CASTAF1 m 148.0 0.707   2   0.5 0.00479 147.0, 148.0 0.45
CASTB6F1 f 145.0 0.0   1   0.0 0.0 145.0, 145.0 -0.87
CASTB6F1 m 149.0 0.577   3 0.333 0.00387 149.0, 150.0 0.86
CAST/EiJ f 148.0 2.17   5 0.97 0.0146 145.0, 150.0 1.25
CAST/EiJ m 147.0 0.0   2   0.0 0.0 147.0, 147.0 0.04
CASTNODF1 m 149.0 0.0   1   0.0 0.0 149.0, 149.0 0.86
CASTNZOF1 f 146.0 1.29   4 0.645 0.00881 145.0, 148.0 -0.16
CASTNZOF1 m 148.0 0.0   1   0.0 0.0 148.0, 148.0 0.45
CASTPWKF1 f 146.0 0.548   5 0.245 0.00374 146.0, 147.0 -0.16
CASTPWKF1 m 149.0 1.9   6 0.775 0.0127 146.0, 151.0 0.86
CASTWSBF1 f 148.0 2.12   2   1.5 0.0144 146.0, 149.0 1.25
NODAF1 f 145.0 0.0   1   0.0 0.0 145.0, 145.0 -0.87
NODB6F1 f 147.0 1.15   3 0.667 0.00787 146.0, 148.0 0.54
NODNZOF1 f 146.0 1.41   2   1.0 0.00969 145.0, 147.0 -0.16
NODNZOF1 m 146.0 1.41   2   1.0 0.00969 145.0, 147.0 -0.37
NOD/ShiLtJ f 143.0 0.0   1   0.0 0.0 143.0, 143.0 -2.28
NOD/ShiLtJ m 145.0 0.0   1   0.0 0.0 145.0, 145.0 -0.78
NZO129SF1 f 145.0 0.0   1   0.0 0.0 145.0, 145.0 -0.87
NZOAF1 f 145.0 0.0   1   0.0 0.0 145.0, 145.0 -0.87
NZOB6F1 m 140.0 0.0   1   0.0 0.0 140.0, 140.0 -2.83
NZO/HlLtJ m 142.0 0.0   1   0.0 0.0 142.0, 142.0 -2.01
NZONODF1 m 145.0 0.0   1   0.0 0.0 145.0, 145.0 -0.78
NZOWSBF1 f 145.0 1.53   3 0.882 0.0106 143.0, 146.0 -0.87
PWK129SF1 f 146.0 0.0   1   0.0 0.0 146.0, 146.0 -0.16
PWKAF1 f 146.0 0.0   1   0.0 0.0 146.0, 146.0 -0.16
PWKAF1 m 148.0 0.0   1   0.0 0.0 148.0, 148.0 0.45
PWKNODF1 f 147.0 0.0   1   0.0 0.0 147.0, 147.0 0.54
PWK/PhJ m 148.0 4.95   2   3.5 0.0336 144.0, 151.0 0.45
WSB129SF1 f 145.0 0.0   1   0.0 0.0 145.0, 145.0 -0.87
WSBAF1 f 148.0 0.0   1   0.0 0.0 148.0, 148.0 1.25
WSBAF1 m 151.0 0.0   2   0.0 0.0 151.0, 151.0 1.68
WSBB6F1 f 146.0 4.95   2   3.5 0.034 142.0, 149.0 -0.16
WSBB6F1 m 148.0 1.73   3 1.0 0.0117 147.0, 150.0 0.45
WSBCASTF1 m 149.0 0.577   3 0.333 0.00388 148.0, 149.0 0.86
WSB/EiJ f 150.0 1.41   2   1.0 0.00943 149.0, 151.0 2.66
WSB/EiJ m 152.0 2.12   2   1.5 0.014 150.0, 153.0 2.09
WSBNODF1 f 146.0 0.0   1   0.0 0.0 146.0, 146.0 -0.16
WSBNODF1 m 148.0 2.12   2   1.5 0.0144 146.0, 149.0 0.45
WSBNZOF1 f 145.0 0.816   6 0.333 0.00562 144.0, 146.0 -0.87
WSBNZOF1 m 146.0 1.5   4 0.75 0.0103 145.0, 148.0 -0.37
WSBPWKF1 f 148.0 3.54   2   2.5 0.024 145.0, 150.0 1.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129SB6F1 f 146.0 1.1007 148.1918 143.8082
129SB6F1 m 146.5 1.1007 148.6918 144.3082
C57BL/6J f 147.0667 0.4019 147.867 146.2663
C57BL/6J m 144.4242 0.271 144.9638 143.8847
CAST/EiJ f 148.2 0.6961 149.5862 146.8138
CAST/EiJ m 147.0 1.1007 149.1918 144.8082
CASTPWKF1 f 146.4 0.6961 147.7862 145.0138
CASTPWKF1 m 149.0 0.6355 150.2654 147.7346
NODNZOF1 f 146.0 1.1007 148.1918 143.8082
NODNZOF1 m 146.0 1.1007 148.1918 143.8082
WSBB6F1 f 145.5 1.1007 147.6918 143.3082
WSBB6F1 m 148.0 0.8987 149.7896 146.2104
WSB/EiJ f 150.0 1.1007 152.1918 147.8082
WSB/EiJ m 151.5 1.1007 153.6918 149.3082
WSBNZOF1 f 145.3333 0.6355 146.5988 144.0679
WSBNZOF1 m 146.25 0.7783 147.7998 144.7002


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129SB6F1 both 146.25 0.7783 147.7998 144.7002
C57BL/6J both 145.7455 0.2424 146.2281 145.2628
CAST/EiJ both 147.6 0.6512 148.8967 146.3033
CASTPWKF1 both 147.7 0.4713 148.6385 146.7615
NODNZOF1 both 146.0 0.7783 147.5498 144.4502
WSBB6F1 both 146.75 0.7105 148.1648 145.3352
WSB/EiJ both 150.75 0.7783 152.2998 149.2002
WSBNZOF1 both 145.7917 0.5024 146.7921 144.7913




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA