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Project measure / variable:   Threadgill2   GSH_Rx300

ID, description, units MPD:39629   GSH_Rx300   reduced glutathione (GSH)   [µmol/mg]  post-Rx 300 mg/kg  
acetaminophen study
Data set, strains Threadgill2   inbred   5 strains     sex: m     age: 6-8wks
Procedure metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Threadgill2 - reduced glutathione (GSH) post-Rx 300 mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested5 strains
Mean of the strain means8.28   µmol/mg
Median of the strain means8.48   µmol/mg
SD of the strain means± 3.98
Coefficient of variation (CV)0.481
Min–max range of strain means4.11   –   14.1   µmol/mg
Mean sample size per strain5.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 4 318.7921 79.698 6.6796 0.0014
Residuals 20 238.6308 11.9315


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
C3H/HeJ m 14.1 3.47   5 1.55 0.245 10.1, 18.8 1.46
C57BL/6J m 9.61 4.8   5 2.15 0.5 5.74, 17.8 0.34
DBA/2J m 4.11 1.06   5 0.474 0.258 2.45, 5.23 -1.05
LP/J m 5.08 3.23   5 1.44 0.636 2.11, 9.15 -0.8
NZW/LacJ m 8.48 3.6   5 1.61 0.425 4.2, 12.0 0.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
C3H/HeJ m 14.14 1.5448 17.3623 10.9177
C57BL/6J m 9.608 1.5448 12.8303 6.3857
DBA/2J m 4.11 1.5448 7.3323 0.8877
LP/J m 5.082 1.5448 8.3043 1.8597
NZW/LacJ m 8.478 1.5448 11.7003 5.2557




  GWAS USING LINEAR MIXED MODELS