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Project measure / variable:   Gould1   blood_lithium400

ID, description, units MPD:37407   blood_lithium400   serum lithium concentration   [mmol/L]  dose 400 mg/kg  
lithium study
Data set, strains Gould1   inbred   11 strains     sex: m     age: 7-8wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Gould1 - serum lithium concentration dose 400 mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested11 strains
Mean of the strain means1.87   mmol/L
Median of the strain means1.93   mmol/L
SD of the strain means± 0.449
Coefficient of variation (CV)0.240
Min–max range of strain means1.17   –   2.52   mmol/L
Mean sample size per strain7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 10 14.76 1.476 10.8023 < 0.0001
Residuals 72 9.838 0.1366


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S6/SvEvTac m 2.52 0.297   8 0.105 0.118 1.98, 2.97 1.44
A/J m 1.93 0.252   8 0.0891 0.13 1.41, 2.22 0.13
BALB/cJ m 2.4 0.333   8 0.118 0.139 1.92, 3.0 1.18
C3H/HeNHsd m 2.14 0.235   8 0.0831 0.11 1.86, 2.4 0.6
C57BL/6J m 1.33 0.511   8 0.181 0.385 0.57, 1.95 -1.21
CBA/J m 2.08 0.352   8 0.125 0.169 1.56, 2.64 0.46
Crl:CD-1(ICR) m 1.46 0.164   6 0.0669 0.112 1.26, 1.7 -0.92
DBA/2J m 1.92 0.484   7 0.183 0.252 1.32, 2.85 0.11
FVB/NJ m 1.17 0.205   6 0.0839 0.175 0.96, 1.54 -1.56
Hsd:NIHS m 1.48 0.628   8 0.222 0.425 0.33, 2.04 -0.87
NTac:NIHBS m 2.16 0.242   8 0.0855 0.112 1.8, 2.52 0.64


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S6/SvEvTac m 2.5237 0.1307 2.7843 2.2632
A/J m 1.935 0.1307 2.1955 1.6745
BALB/cJ m 2.3962 0.1307 2.6568 2.1357
C3H/HeNHsd m 2.1413 0.1307 2.4018 1.8807
C57BL/6J m 1.3275 0.1307 1.588 1.067
CBA/J m 2.0812 0.1307 2.3418 1.8207
Crl:CD-1(ICR) m 1.46 0.1509 1.7608 1.1592
DBA/2J m 1.92 0.1397 2.1985 1.6415
FVB/NJ m 1.1733 0.1509 1.4742 0.8725
Hsd:NIHS m 1.4775 0.1307 1.738 1.217
NTac:NIHBS m 2.1638 0.1307 2.4243 1.9032




  GWAS USING LINEAR MIXED MODELS