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Project measure / variable:   Bopp1   parasitemia

ID, description, units MPD:36403   parasitemia   percentage of parasite-infected erythrocytes in blood   [%]  
Plasmodium berghei study
Data set, strains Bopp1   inbred   31 strains     sex: both     age: 8-12wks
Procedure health assessment
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  STRAIN COMPARISON PLOT
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Bopp1 - percentage of parasite-infected erythrocytes in blood



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested31 strains31 strains
Mean of the strain means53.4   % 53.2   %
Median of the strain means53.2   % 51.2   %
SD of the strain means± 11.9 ± 12.9
Coefficient of variation (CV)0.222 0.242
Min–max range of strain means27.7   –   74.9   % 26.7   –   77.7   %
Mean sample size per strain3.8   mice 3.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 28.7764 28.7764 0.1829 0.6694
strain 30 24969.4951 832.3165 5.2898 < 0.0001
sex:strain 30 9012.5249 300.4175 1.9093 0.0055
Residuals 172 27063.2525 157.3445


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 56.3 9.74   4 4.87 0.173 43.0, 66.4 0.24
129S1/SvImJ m 48.6 14.3   4 7.15 0.294 29.6, 63.9 -0.35
A/J f 71.5 9.3   4 4.65 0.13 58.8, 78.5 1.52
A/J m 75.3 2.55   3 1.47 0.0339 72.8, 77.9 1.72
AKR/J f 47.6 3.99   4 2.0 0.0839 42.3, 52.0 -0.49
AKR/J m 42.0 2.82   4 1.41 0.067 39.5, 45.6 -0.87
BALB/cByJ f 61.6 5.19   4 2.59 0.0843 55.1, 65.8 0.69
BALB/cByJ m 47.1 8.93   4 4.47 0.19 34.5, 54.8 -0.47
BTBR T+ Itpr3tf/J f 58.9 8.83   4 4.42 0.15 50.0, 68.0 0.46
BTBR T+ Itpr3tf/J m 61.4 5.34   4 2.67 0.087 55.4, 66.0 0.64
BUB/BnJ f 59.8 9.84   3 5.68 0.164 48.5, 66.2 0.54
BUB/BnJ m 49.0 25.9   4 12.9 0.529 11.8, 71.9 -0.32
C3H/HeJ f 67.5 6.69   4 3.34 0.0991 61.4, 73.8 1.18
C3H/HeJ m 67.1 12.2   4 6.08 0.181 49.3, 76.7 1.08
C57BL/6J f 42.7 8.7   4 4.35 0.204 33.6, 54.5 -0.9
C57BL/6J m 26.7 15.7   4 7.86 0.589 12.8, 42.8 -2.05
C57BR/cdJ f 55.8 16.8   4 8.38 0.3 39.6, 74.1 0.2
C57BR/cdJ m 77.7 2.68   4 1.34 0.0344 74.6, 81.1 1.9
C58/J f 73.8 14.1   4 7.03 0.191 54.4, 87.9 1.71
C58/J m 74.8 3.19   4 1.6 0.0427 71.1, 78.4 1.68
CBA/J f 53.0 3.91   4 1.95 0.0738 49.2, 57.7 -0.04
CBA/J m 63.1 15.0   4 7.49 0.237 51.2, 85.0 0.77
CZECHII/EiJ f 59.9 16.8   2   11.9 0.28 48.0, 71.7 0.54
CZECHII/EiJ m 71.3 1.36   3 0.784 0.0191 69.7, 72.1 1.41
DBA/2J f 67.0 5.75   4 2.87 0.0858 60.6, 74.2 1.14
DBA/2J m 52.0 3.75   4 1.87 0.0721 48.0, 56.2 -0.09
FVB/NJ f 53.3 10.1   4 5.05 0.19 43.4, 66.7 -0.01
FVB/NJ m 60.2 9.01   4 4.5 0.149 48.2, 68.0 0.55
I/LnJ f 47.2 2.37   3 1.37 0.0503 45.0, 49.7 -0.52
I/LnJ m 52.9 9.97   3 5.75 0.188 41.5, 60.1 -0.02
KK/HlJ f 57.4 2.48   4 1.24 0.0431 54.5, 60.4 0.33
KK/HlJ m 55.1 18.6   4 9.29 0.337 31.1, 73.2 0.15
LG/J f 35.7 8.8   4 4.4 0.247 24.4, 42.7 -1.49
LG/J m 51.2 8.99   4 4.5 0.176 41.6, 63.3 -0.15
MA/MyJ f 51.9 3.62   3 2.09 0.0697 48.1, 55.3 -0.13
MA/MyJ m 45.9 10.1   3 5.84 0.22 36.5, 56.6 -0.56
MRL/MpJ f 51.0 2.68   4 1.34 0.0526 48.2, 53.3 -0.2
MRL/MpJ m 43.8 38.1   4 19.0 0.871 20.0, 100.0 -0.73
NOD/ShiLtJ f 39.6 4.08   4 2.04 0.103 34.8, 44.6 -1.16
NOD/ShiLtJ m 47.9 19.6   4 9.78 0.408 27.9, 65.6 -0.41
NON/ShiLtJ f 42.0 9.67   4 4.83 0.23 28.4, 51.3 -0.96
NON/ShiLtJ m 41.1 2.15   4 1.07 0.0522 38.0, 42.7 -0.94
NZO/HlLtJ f 43.3 19.2   4 9.62 0.444 19.1, 65.7 -0.85
NZO/HlLtJ m 31.9 13.9   4 6.95 0.435 11.3, 41.2 -1.65
NZW/LacJ f 74.9 8.46   3 4.88 0.113 66.6, 83.5 1.81
NZW/LacJ m 61.2 14.9   4 7.45 0.243 42.9, 79.3 0.62
PERA/EiJ f 38.0 19.4   4 9.72 0.512 17.1, 63.9 -1.3
PERA/EiJ m 44.8 24.3   4 12.2 0.542 18.3, 66.3 -0.65
P/J f 39.1 13.4   4 6.69 0.342 23.2, 52.3 -1.21
P/J m 60.7 7.04   4 3.52 0.116 53.2, 67.2 0.58
PL/J f 46.3 9.68   3 5.59 0.209 36.2, 55.5 -0.6
PL/J m 47.6 22.4   3 12.9 0.47 27.0, 71.4 -0.43
RIIIS/J f 27.7 14.0   2   9.9 0.505 17.8, 37.6 -2.16
RIIIS/J m 59.2 6.22   4 3.11 0.105 52.5, 66.8 0.47
SJL/J f 49.6 14.7   4 7.33 0.296 31.9, 63.4 -0.32
SJL/J m 40.6 11.2   4 5.59 0.276 24.6, 50.7 -0.97
SM/J f 53.2 7.55   4 3.78 0.142 44.9, 60.8 -0.02
SM/J m 33.6 16.0   4 8.01 0.477 18.2, 56.0 -1.52
SWR/J f 70.5 5.91   4 2.95 0.0838 61.7, 74.6 1.44
SWR/J m 47.7 4.7   4 2.35 0.0987 42.1, 52.9 -0.42
WSB/EiJ f 60.4 12.6   4 6.32 0.209 41.5, 68.4 0.59
WSB/EiJ m 66.7 8.46   4 4.23 0.127 58.7, 75.8 1.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 56.325 6.2719 68.7047 43.9453
129S1/SvImJ m 48.6 6.2719 60.9797 36.2203
A/J f 71.475 6.2719 83.8547 59.0953
A/J m 75.3 7.2421 89.5949 61.0051
AKR/J f 47.575 6.2719 59.9547 35.1953
AKR/J m 42.05 6.2719 54.4297 29.6703
BALB/cByJ f 61.55 6.2719 73.9297 49.1703
BALB/cByJ m 47.1 6.2719 59.4797 34.7203
BTBR T+ Itpr3tf/J f 58.9 6.2719 71.2797 46.5203
BTBR T+ Itpr3tf/J m 61.4 6.2719 73.7797 49.0203
BUB/BnJ f 59.8333 7.2421 74.1282 45.5385
BUB/BnJ m 48.95 6.2719 61.3297 36.5703
C3H/HeJ f 67.475 6.2719 79.8547 55.0953
C3H/HeJ m 67.125 6.2719 79.5047 54.7453
C57BL/6J f 42.675 6.2719 55.0547 30.2953
C57BL/6J m 26.675 6.2719 39.0547 14.2953
C57BR/cdJ f 55.775 6.2719 68.1547 43.3953
C57BR/cdJ m 77.725 6.2719 90.1047 65.3453
C58/J f 73.775 6.2719 86.1547 61.3953
C58/J m 74.825 6.2719 87.2047 62.4453
CBA/J f 52.975 6.2719 65.3547 40.5953
CBA/J m 63.075 6.2719 75.4547 50.6953
CZECHII/EiJ f 59.85 8.8697 77.3576 42.3424
CZECHII/EiJ m 71.2667 7.2421 85.5615 56.9718
DBA/2J f 67.025 6.2719 79.4047 54.6453
DBA/2J m 51.975 6.2719 64.3547 39.5953
FVB/NJ f 53.25 6.2719 65.6297 40.8703
FVB/NJ m 60.25 6.2719 72.6297 47.8703
I/LnJ f 47.1667 7.2421 61.4615 32.8718
I/LnJ m 52.8667 7.2421 67.1615 38.5718
KK/HlJ f 57.425 6.2719 69.8047 45.0453
KK/HlJ m 55.15 6.2719 67.5297 42.7703
LG/J f 35.65 6.2719 48.0297 23.2703
LG/J m 51.175 6.2719 63.5547 38.7953
MA/MyJ f 51.9 7.2421 66.1949 37.6051
MA/MyJ m 45.9333 7.2421 60.2282 31.6385
MRL/MpJ f 50.95 6.2719 63.3297 38.5703
MRL/MpJ m 43.75 6.2719 56.1297 31.3703
NOD/ShiLtJ f 39.6 6.2719 51.9797 27.2203
NOD/ShiLtJ m 47.925 6.2719 60.3047 35.5453
NON/ShiLtJ f 41.975 6.2719 54.3547 29.5953
NON/ShiLtJ m 41.15 6.2719 53.5297 28.7703
NZO/HlLtJ f 43.325 6.2719 55.7047 30.9453
NZO/HlLtJ m 31.925 6.2719 44.3047 19.5453
NZW/LacJ f 74.8667 7.2421 89.1615 60.5718
NZW/LacJ m 61.225 6.2719 73.6047 48.8453
PERA/EiJ f 37.975 6.2719 50.3547 25.5953
PERA/EiJ m 44.825 6.2719 57.2047 32.4453
P/J f 39.15 6.2719 51.5297 26.7703
P/J m 60.65 6.2719 73.0297 48.2703
PL/J f 46.3 7.2421 60.5949 32.0051
PL/J m 47.6 7.2421 61.8949 33.3051
RIIIS/J f 27.7 8.8697 45.2076 10.1924
RIIIS/J m 59.2 6.2719 71.5797 46.8203
SJL/J f 49.575 6.2719 61.9547 37.1953
SJL/J m 40.575 6.2719 52.9547 28.1953
SM/J f 53.225 6.2719 65.6047 40.8453
SM/J m 33.625 6.2719 46.0047 21.2453
SWR/J f 70.45 6.2719 82.8297 58.0703
SWR/J m 47.65 6.2719 60.0297 35.2703
WSB/EiJ f 60.35 6.2719 72.7297 47.9703
WSB/EiJ m 66.725 6.2719 79.1047 54.3453


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 52.4625 4.4349 61.2163 43.7087
A/J both 73.3875 4.7902 82.8427 63.9323
AKR/J both 44.8125 4.4349 53.5663 36.0587
BALB/cByJ both 54.325 4.4349 63.0788 45.5712
BTBR T+ Itpr3tf/J both 60.15 4.4349 68.9038 51.3962
BUB/BnJ both 54.3917 4.7902 63.8468 44.9365
C3H/HeJ both 67.3 4.4349 76.0538 58.5462
C57BL/6J both 34.675 4.4349 43.4288 25.9212
C57BR/cdJ both 66.75 4.4349 75.5038 57.9962
C58/J both 74.3 4.4349 83.0538 65.5462
CBA/J both 58.025 4.4349 66.7788 49.2712
CZECHII/EiJ both 65.5583 5.7254 76.8594 54.2573
DBA/2J both 59.5 4.4349 68.2538 50.7462
FVB/NJ both 56.75 4.4349 65.5038 47.9962
I/LnJ both 50.0167 5.1209 60.1247 39.9087
KK/HlJ both 56.2875 4.4349 65.0413 47.5337
LG/J both 43.4125 4.4349 52.1663 34.6587
MA/MyJ both 48.9167 5.1209 59.0247 38.8087
MRL/MpJ both 47.35 4.4349 56.1038 38.5962
NOD/ShiLtJ both 43.7625 4.4349 52.5163 35.0087
NON/ShiLtJ both 41.5625 4.4349 50.3163 32.8087
NZO/HlLtJ both 37.625 4.4349 46.3788 28.8712
NZW/LacJ both 68.0458 4.7902 77.501 58.5907
PERA/EiJ both 41.4 4.4349 50.1538 32.6462
P/J both 49.9 4.4349 58.6538 41.1462
PL/J both 46.95 5.1209 57.058 36.842
RIIIS/J both 43.45 5.4316 54.1711 32.7289
SJL/J both 45.075 4.4349 53.8288 36.3212
SM/J both 43.425 4.4349 52.1788 34.6712
SWR/J both 59.05 4.4349 67.8038 50.2962
WSB/EiJ both 63.5375 4.4349 72.2913 54.7837




  GWAS USING LINEAR MIXED MODELS