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Project measure / variable:   Rusyn2   DCV_glutathione8_tce

ID, description, units MPD:36196   DCV_glutathione8_tce   DCV glutathione (serum DCVG x 10-3)   [nmol/mL]  8h after treatment  
trichloroethylene study
Data set, strains Rusyn2   inbred   16 strains     sex: m     age: 7wks
Procedure drug and metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Rusyn2 - DCV glutathione (serum DCVG x 10-3) 8h after treatment



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested16 strains
Mean of the strain means1.86   nmol/mL
Median of the strain means0.360   nmol/mL
SD of the strain means± 4.62
Coefficient of variation (CV)2.49
Min–max range of strain means0.0712   –   19.0   nmol/mL
Mean sample size per strain2.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 13 935.5708 71.967 115.2077 < 0.0001
Residuals 23 14.3675 0.6247


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 1.87 2.07   3 1.19 1.11 0.323, 4.22 0.0
A/J m 0.169 0.0113   2   0.008 0.0669 0.161, 0.177 -0.36
AKR/J m 0.313 0.361   2   0.255 1.15 0.0576, 0.568 -0.33
B6C3F1/J m 19.0 1.5   3 0.866 0.0789 17.5, 20.5 3.71
BALB/cByJ m 0.611 0.695   3 0.401 1.14 0.0046, 1.37 -0.27
BTBR T+ Itpr3tf/J m 1.13 0.0173   3 0.01 0.0153 1.11, 1.14 -0.16
C3H/HeJ m 0.14 0.0299   3 0.0173 0.213 0.106, 0.161 -0.37
C57BL/6J m 0.352 0.0995   3 0.0575 0.283 0.259, 0.457 -0.33
CAST/EiJ m 0.153 0.0   1   0.0 0.0 0.153, 0.153 -0.37
DBA/2J m 0.0712 0.0155   3 0.00897 0.218 0.0544, 0.085 -0.39
FVB/NJ m 0.269 0.309   3 0.179 1.15 0.0755, 0.626 -0.34
KK/HlJ m 0.368 0.0   2   0.0 0.0 0.368, 0.368 -0.32
MOLF/EiJ m 1.75 0.0   2   0.0 0.0 1.75, 1.75 -0.02
NOD/ShiLtJ m 0.94 0.0   1   0.0 0.0 0.94, 0.94 -0.2
NZW/LacJ m 0.287 0.0   2   0.0 0.0 0.287, 0.287 -0.34
WSB/EiJ m 2.28 0.0   3 0.0 0.0 2.28, 2.28 0.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 1.871 0.4563 2.815 0.927
A/J m 0.169 0.5589 1.3251 0.0
AKR/J m 0.3128 0.5589 1.4689 0.0
B6C3F1/J m 19.0 0.4563 19.944 18.056
BALB/cByJ m 0.6109 0.4563 1.5548 0.0
BTBR T+ Itpr3tf/J m 1.13 0.4563 2.074 0.186
C3H/HeJ m 0.1403 0.4563 1.0843 0.0
C57BL/6J m 0.352 0.4563 1.296 0.0
DBA/2J m 0.0712 0.4563 1.0152 0.0
FVB/NJ m 0.2692 0.4563 1.2131 0.0
KK/HlJ m 0.368 0.5589 1.5241 0.0
MOLF/EiJ m 1.75 0.5589 2.9061 0.5939
NZW/LacJ m 0.287 0.5589 1.4431 0.0
WSB/EiJ m 2.28 0.4563 3.224 1.336




  GWAS USING LINEAR MIXED MODELS