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Project measure / variable:   Koide2   capsaicin_15

ID, description, units MPD:35807   capsaicin_15   capsaicin solution consumption, percentage of baseline   [%]  concentration: 15 µM  
Data set, strains Koide2   wild-derived Mishima   14 strains     sex: both     age: 8-12wks
Procedure nociception assay
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  STRAIN COMPARISON PLOT
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Koide2 - capsaicin solution consumption, percentage of baseline concentration: 15 µM



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested14 strains14 strains
Mean of the strain means33.9   % 34.7   %
Median of the strain means34.6   % 34.8   %
SD of the strain means± 16.6 ± 18.5
Coefficient of variation (CV)0.489 0.532
Min–max range of strain means8.03   –   59.4   % 6.83   –   65.2   %
Mean sample size per strain10.0   mice 10.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 41.4876 41.4876 0.1031 0.7484
strain 13 78315.5943 6024.2765 14.971 < 0.0001
sex:strain 13 1663.0635 127.928 0.3179 0.989
Residuals 252 101403.685 402.3956


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BALB/cAnN f 28.7 17.6   10 5.57 0.614 10.1, 67.2 -0.31
BALB/cAnN m 24.7 15.9   10 5.04 0.646 7.53, 56.9 -0.54
BFM/2Ms f 26.0 17.2   10 5.43 0.66 7.49, 58.7 -0.48
BFM/2Ms m 30.4 29.7   10 9.38 0.976 7.81, 106.0 -0.23
BLG2/Ms f 48.0 6.41   10 2.03 0.134 39.7, 62.2 0.85
BLG2/Ms m 45.9 17.4   10 5.51 0.38 8.89, 61.9 0.61
C57BL/6J f 11.4 6.12   10 1.94 0.536 5.61, 22.0 -1.36
C57BL/6J m 8.85 6.35   10 2.01 0.718 5.22, 26.2 -1.4
CAST/EiJ f 47.7 14.5   10 4.59 0.304 16.0, 67.1 0.83
CAST/EiJ m 44.2 19.5   10 6.16 0.441 14.6, 73.0 0.52
CHD/Ms f 39.8 21.6   10 6.82 0.542 7.82, 69.3 0.36
CHD/Ms m 47.0 17.1   10 5.4 0.363 6.1, 66.2 0.67
DBA/1J f 10.4 3.6   10 1.14 0.347 6.22, 16.8 -1.42
DBA/1J m 9.22 3.3   10 1.04 0.358 4.56, 14.2 -1.38
HMI/Ms f 26.1 23.0   10 7.29 0.884 6.15, 66.3 -0.47
HMI/Ms m 31.0 27.2   10 8.59 0.876 7.55, 84.9 -0.2
JF1/MsJ f 32.4 19.0   10 6.02 0.588 13.5, 64.1 -0.09
JF1/MsJ m 38.6 41.6   10 13.2 1.08 5.56, 142.0 0.21
KJR/Ms f 59.4 21.6   10 6.82 0.363 15.2, 90.0 1.54
KJR/Ms m 62.2 16.5   10 5.21 0.265 32.6, 85.7 1.49
MSM/MsJ f 56.9 14.2   10 4.48 0.249 40.3, 80.6 1.39
MSM/MsJ m 65.2 37.0   10 11.7 0.568 32.8, 166.0 1.65
NJL/Ms f 36.9 26.2   10 8.27 0.709 6.54, 79.8 0.18
NJL/Ms m 27.5 15.2   10 4.82 0.554 5.42, 46.5 -0.39
PGN2/Ms f 8.03 2.62   10 0.83 0.327 5.47, 14.8 -1.56
PGN2/Ms m 6.83 2.0   10 0.631 0.292 4.28, 10.2 -1.51
SWN/Ms f 42.7 26.7   10 8.46 0.626 9.54, 81.6 0.53
SWN/Ms m 43.7 20.6   10 6.51 0.471 7.25, 65.1 0.49


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BALB/cAnN f 28.68 6.3435 41.173 16.187
BALB/cAnN m 24.68 6.3435 37.173 12.187
BFM/2Ms f 26.019 6.3435 38.512 13.526
BFM/2Ms m 30.411 6.3435 42.904 17.918
BLG2/Ms f 47.96 6.3435 60.453 35.467
BLG2/Ms m 45.899 6.3435 58.392 33.406
C57BL/6J f 11.43 6.3435 23.923 0.0
C57BL/6J m 8.847 6.3435 21.34 0.0
CAST/EiJ f 47.72 6.3435 60.213 35.227
CAST/EiJ m 44.2 6.3435 56.693 31.707
CHD/Ms f 39.764 6.3435 52.257 27.271
CHD/Ms m 47.0 6.3435 59.493 34.507
DBA/1J f 10.37 6.3435 22.863 0.0
DBA/1J m 9.217 6.3435 21.71 0.0
HMI/Ms f 26.053 6.3435 38.546 13.56
HMI/Ms m 30.985 6.3435 43.478 18.492
JF1/MsJ f 32.4 6.3435 44.893 19.907
JF1/MsJ m 38.635 6.3435 51.128 26.142
KJR/Ms f 59.44 6.3435 71.933 46.947
KJR/Ms m 62.17 6.3435 74.663 49.677
MSM/MsJ f 56.94 6.3435 69.433 44.447
MSM/MsJ m 65.15 6.3435 77.643 52.657
NJL/Ms f 36.881 6.3435 49.374 24.388
NJL/Ms m 27.489 6.3435 39.982 14.996
PGN2/Ms f 8.031 6.3435 20.524 0.0
PGN2/Ms m 6.829 6.3435 19.322 0.0
SWN/Ms f 42.724 6.3435 55.217 30.231
SWN/Ms m 43.678 6.3435 56.171 31.185


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BALB/cAnN both 26.68 4.4855 35.5139 17.8461
BFM/2Ms both 28.215 4.4855 37.0489 19.3811
BLG2/Ms both 46.9295 4.4855 55.7634 38.0956
C57BL/6J both 10.1385 4.4855 18.9724 1.3046
CAST/EiJ both 45.96 4.4855 54.7939 37.1261
CHD/Ms both 43.382 4.4855 52.2159 34.5481
DBA/1J both 9.7935 4.4855 18.6274 0.9596
HMI/Ms both 28.519 4.4855 37.3529 19.6851
JF1/MsJ both 35.5175 4.4855 44.3514 26.6836
KJR/Ms both 60.805 4.4855 69.6389 51.9711
MSM/MsJ both 61.045 4.4855 69.8789 52.2111
NJL/Ms both 32.185 4.4855 41.0189 23.3511
PGN2/Ms both 7.43 4.4855 16.2639 0.0
SWN/Ms both 43.201 4.4855 52.0349 34.3671




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA