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Project measure / variable:   Berndt2   duty_cycle_mch10

ID, description, units MPD:35136   duty_cycle_mch10   duty cycle   [ratio]  10 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - duty cycle 10 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.318   ratio 0.341   ratio
Median of the strain means0.315   ratio 0.347   ratio
SD of the strain means± 0.0397 ± 0.0315
Coefficient of variation (CV)0.125 0.0924
Min–max range of strain means0.229   –   0.403   ratio 0.269   –   0.397   ratio
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0536 0.0536 53.3969 < 0.0001
strain 28 0.5343 0.0191 19.0016 < 0.0001
sex:strain 28 0.0534 0.0019 1.898 0.0043
Residuals 412 0.4137 0.001


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.294 0.0461   8 0.0163 0.156 0.254, 0.388 -0.61
129S1/SvImJ m 0.349 0.0215   8 0.00761 0.0617 0.313, 0.376 0.26
A/J f 0.368 0.0398   8 0.0141 0.108 0.322, 0.449 1.25
A/J m 0.376 0.0336   8 0.0119 0.0895 0.34, 0.429 1.12
AKR/J f 0.357 0.037   8 0.0131 0.104 0.325, 0.438 0.98
AKR/J m 0.353 0.0255   8 0.00903 0.0725 0.329, 0.392 0.39
BALB/cByJ f 0.335 0.0194   8 0.00687 0.058 0.31, 0.36 0.42
BALB/cByJ m 0.336 0.0307   8 0.0108 0.0911 0.308, 0.395 -0.15
BALB/cJ f 0.343 0.0282   10 0.0089 0.0822 0.287, 0.388 0.62
BALB/cJ m 0.369 0.0251   10 0.00795 0.0681 0.344, 0.415 0.89
BTBR T+ Itpr3tf/J f 0.368 0.0294   8 0.0104 0.08 0.33, 0.411 1.25
BTBR T+ Itpr3tf/J m 0.388 0.0287   8 0.0101 0.074 0.32, 0.413 1.5
BUB/BnJ f 0.315 0.0249   7 0.00941 0.0791 0.278, 0.345 -0.08
BUB/BnJ m 0.346 0.0272   8 0.00961 0.0785 0.295, 0.386 0.16
C3H/HeJ f 0.302 0.0286   8 0.0101 0.0948 0.26, 0.349 -0.41
C3H/HeJ m 0.289 0.0374   8 0.0132 0.13 0.214, 0.345 -1.65
C57BL/10J f 0.288 0.0263   8 0.00928 0.091 0.252, 0.331 -0.76
C57BL/10J m 0.357 0.015   7 0.00566 0.0419 0.332, 0.379 0.51
C57BL/6J f 0.285 0.0277   7 0.0105 0.097 0.237, 0.33 -0.84
C57BL/6J m 0.301 0.0383   13 0.0106 0.127 0.24, 0.37 -1.27
C57BLKS/J f 0.32 0.0243   11 0.00732 0.0759 0.285, 0.356 0.04
C57BLKS/J m 0.355 0.0429   8 0.0152 0.121 0.282, 0.402 0.45
C57BR/cdJ f 0.302 0.0438   6 0.0179 0.145 0.237, 0.36 -0.41
C57BR/cdJ m 0.324 0.0419   8 0.0148 0.129 0.267, 0.396 -0.54
C57L/J f 0.305 0.0314   8 0.0111 0.103 0.259, 0.345 -0.34
C57L/J m 0.34 0.0349   8 0.0124 0.103 0.278, 0.379 -0.03
CBA/J f 0.35 0.022   8 0.00779 0.0629 0.333, 0.397 0.8
CBA/J m 0.361 0.0266   8 0.00941 0.0737 0.309, 0.397 0.64
CE/J f 0.315 0.0394   8 0.0139 0.125 0.245, 0.353 -0.08
CE/J m 0.329 0.0284   9 0.00945 0.0861 0.301, 0.382 -0.38
DBA/1J f 0.369 0.0377   10 0.0119 0.102 0.306, 0.429 1.28
DBA/1J m 0.37 0.0363   8 0.0128 0.0983 0.298, 0.414 0.93
DBA/2J f 0.346 0.0238   8 0.00841 0.0687 0.301, 0.376 0.7
DBA/2J m 0.375 0.034   10 0.0108 0.0908 0.322, 0.424 1.08
FVB/NJ f 0.3 0.0247   8 0.00874 0.0825 0.262, 0.328 -0.46
FVB/NJ m 0.367 0.0176   7 0.00663 0.0478 0.338, 0.39 0.83
I/LnJ f 0.326 0.0439   7 0.0166 0.135 0.274, 0.399 0.19
I/LnJ m 0.319 0.0329   5 0.0147 0.103 0.267, 0.348 -0.69
KK/HlJ f 0.309 0.0196   8 0.00693 0.0633 0.283, 0.337 -0.23
KK/HlJ m 0.337 0.0564   6 0.023 0.167 0.242, 0.396 -0.12
LP/J f 0.27 0.0217   8 0.00767 0.0804 0.223, 0.289 -1.22
LP/J m 0.321 0.0262   8 0.00927 0.0816 0.294, 0.376 -0.63
NOD/ShiLtJ f 0.284 0.0218   8 0.00772 0.0769 0.246, 0.318 -0.87
NOD/ShiLtJ m 0.322 0.0305   8 0.0108 0.0948 0.273, 0.363 -0.6
NON/ShiLtJ f 0.229 0.0305   8 0.0108 0.133 0.175, 0.27 -2.25
NON/ShiLtJ m 0.274 0.0375   8 0.0132 0.137 0.216, 0.321 -2.12
NZW/LacJ f 0.317 0.0526   8 0.0186 0.166 0.209, 0.362 -0.03
NZW/LacJ m 0.347 0.0373   8 0.0132 0.107 0.266, 0.387 0.19
PL/J f 0.229 0.0273   8 0.00965 0.119 0.189, 0.27 -2.25
PL/J m 0.269 0.0269   8 0.00951 0.1 0.226, 0.304 -2.28
RIIIS/J f 0.357 0.0254   8 0.00899 0.0713 0.317, 0.385 0.98
RIIIS/J m 0.353 0.028   8 0.00989 0.0793 0.318, 0.39 0.39
SJL/J f 0.309 0.0274   8 0.00969 0.0887 0.26, 0.342 -0.23
SJL/J m 0.314 0.0256   8 0.00907 0.0817 0.275, 0.352 -0.85
SM/J f 0.403 0.0275   8 0.00974 0.0684 0.368, 0.433 2.14
SM/J m 0.397 0.0282   8 0.00998 0.0711 0.354, 0.426 1.78
SWR/J f 0.336 0.0399   8 0.0141 0.119 0.294, 0.402 0.45
SWR/J m 0.347 0.0133   9 0.00443 0.0383 0.332, 0.371 0.19


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2945 0.0112 0.3165 0.2725
129S1/SvImJ m 0.3489 0.0112 0.3709 0.3269
A/J f 0.3685 0.0112 0.3905 0.3465
A/J m 0.3755 0.0112 0.3975 0.3535
AKR/J f 0.357 0.0112 0.379 0.335
AKR/J m 0.3525 0.0112 0.3745 0.3305
BALB/cByJ f 0.3351 0.0112 0.3571 0.3131
BALB/cByJ m 0.3365 0.0112 0.3585 0.3145
BALB/cJ f 0.3426 0.01 0.3623 0.3229
BALB/cJ m 0.3694 0.01 0.3891 0.3497
BTBR T+ Itpr3tf/J f 0.3679 0.0112 0.3899 0.3459
BTBR T+ Itpr3tf/J m 0.3877 0.0112 0.4098 0.3657
BUB/BnJ f 0.3149 0.012 0.3384 0.2913
BUB/BnJ m 0.3459 0.0112 0.3679 0.3239
C3H/HeJ f 0.3017 0.0112 0.3238 0.2797
C3H/HeJ m 0.2885 0.0112 0.3105 0.2665
C57BL/10J f 0.2885 0.0112 0.3105 0.2665
C57BL/10J m 0.3574 0.012 0.381 0.3339
C57BL/6J f 0.2853 0.012 0.3088 0.2617
C57BL/6J m 0.3006 0.0088 0.3179 0.2833
C57BLKS/J f 0.32 0.0096 0.3388 0.3012
C57BLKS/J m 0.3554 0.0112 0.3774 0.3334
C57BR/cdJ f 0.3022 0.0129 0.3276 0.2767
C57BR/cdJ m 0.324 0.0112 0.346 0.302
C57L/J f 0.3045 0.0112 0.3265 0.2825
C57L/J m 0.3396 0.0112 0.3616 0.3176
CBA/J f 0.35 0.0112 0.372 0.328
CBA/J m 0.3611 0.0112 0.3831 0.3391
CE/J f 0.3149 0.0112 0.3369 0.2929
CE/J m 0.3294 0.0106 0.3502 0.3087
DBA/1J f 0.3687 0.01 0.3884 0.349
DBA/1J m 0.3697 0.0112 0.3918 0.3477
DBA/2J f 0.3461 0.0112 0.3681 0.3241
DBA/2J m 0.3748 0.01 0.3945 0.3551
FVB/NJ f 0.2999 0.0112 0.3219 0.2779
FVB/NJ m 0.3669 0.012 0.3904 0.3433
I/LnJ f 0.3257 0.012 0.3493 0.3022
I/LnJ m 0.3188 0.0142 0.3467 0.2909
KK/HlJ f 0.3095 0.0112 0.3315 0.2875
KK/HlJ m 0.3373 0.0129 0.3628 0.3119
LP/J f 0.27 0.0112 0.292 0.248
LP/J m 0.3212 0.0112 0.3433 0.2992
NOD/ShiLtJ f 0.284 0.0112 0.306 0.262
NOD/ShiLtJ m 0.3221 0.0112 0.3441 0.3001
NON/ShiLtJ f 0.2294 0.0112 0.2514 0.2074
NON/ShiLtJ m 0.2736 0.0112 0.2956 0.2516
NZW/LacJ f 0.3171 0.0112 0.3391 0.2951
NZW/LacJ m 0.3475 0.0112 0.3695 0.3255
PL/J f 0.229 0.0112 0.251 0.207
PL/J m 0.2689 0.0112 0.2909 0.2469
RIIIS/J f 0.3569 0.0112 0.3789 0.3349
RIIIS/J m 0.3529 0.0112 0.3749 0.3309
SJL/J f 0.3092 0.0112 0.3313 0.2872
SJL/J m 0.3139 0.0112 0.3359 0.2919
SM/J f 0.4027 0.0112 0.4248 0.3807
SM/J m 0.3971 0.0112 0.4191 0.3751
SWR/J f 0.3359 0.0112 0.3579 0.3139
SWR/J m 0.3469 0.0106 0.3677 0.3261


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.3217 0.0079 0.3373 0.3061
A/J both 0.372 0.0079 0.3876 0.3564
AKR/J both 0.3547 0.0079 0.3703 0.3392
BALB/cByJ both 0.3358 0.0079 0.3514 0.3202
BALB/cJ both 0.356 0.0071 0.3699 0.3421
BTBR T+ Itpr3tf/J both 0.3778 0.0079 0.3934 0.3622
BUB/BnJ both 0.3304 0.0082 0.3465 0.3142
C3H/HeJ both 0.2951 0.0079 0.3107 0.2796
C57BL/10J both 0.323 0.0082 0.3391 0.3068
C57BL/6J both 0.293 0.0074 0.3076 0.2783
C57BLKS/J both 0.3377 0.0074 0.3522 0.3232
C57BR/cdJ both 0.3131 0.0086 0.3299 0.2963
C57L/J both 0.3221 0.0079 0.3376 0.3065
CBA/J both 0.3556 0.0079 0.3711 0.34
CE/J both 0.3222 0.0077 0.3373 0.307
DBA/1J both 0.3692 0.0075 0.384 0.3545
DBA/2J both 0.3605 0.0075 0.3752 0.3457
FVB/NJ both 0.3334 0.0082 0.3495 0.3172
I/LnJ both 0.3223 0.0093 0.3405 0.304
KK/HlJ both 0.3234 0.0086 0.3402 0.3066
LP/J both 0.2956 0.0079 0.3112 0.2801
NOD/ShiLtJ both 0.3031 0.0079 0.3186 0.2875
NON/ShiLtJ both 0.2515 0.0079 0.2671 0.2359
NZW/LacJ both 0.3323 0.0079 0.3479 0.3167
PL/J both 0.2489 0.0079 0.2645 0.2334
RIIIS/J both 0.3549 0.0079 0.3704 0.3393
SJL/J both 0.3116 0.0079 0.3271 0.296
SM/J both 0.3999 0.0079 0.4155 0.3844
SWR/J both 0.3414 0.0077 0.3565 0.3262




  GWAS USING LINEAR MIXED MODELS