Project measure / variable:   Berndt2   tot_respi_mch20

ID, description, units MPD:35131   tot_respi_mch20   respiratory cycle   [s]  20 MCh  
methacholine study
Data set, strains Berndt2   inbred   29 strains     sex: both     age: 9-12wks
Procedure plethysmography
Ontology mappings

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  STRAIN COMPARISON PLOT
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Berndt2 - respiratory cycle 20 MCh



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested29 strains29 strains
Mean of the strain means0.297   s 0.294   s
Median of the strain means0.287   s 0.272   s
SD of the strain means± 0.0721 ± 0.0710
Coefficient of variation (CV)0.243 0.241
Min–max range of strain means0.204   –   0.457   s 0.197   –   0.483   s
Mean sample size per strain8.0   mice 8.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0021 0.0021 0.4342 0.5103
strain 28 2.0985 0.0749 15.6468 < 0.0001
sex:strain 28 0.2374 0.0085 1.7703 0.01
Residuals 412 1.9734 0.0048


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.293 0.0491   8 0.0174 0.168 0.218, 0.352 -0.05
129S1/SvImJ m 0.286 0.0698   8 0.0247 0.244 0.213, 0.44 -0.12
A/J f 0.432 0.136   8 0.0479 0.313 0.274, 0.631 1.87
A/J m 0.483 0.0883   8 0.0312 0.183 0.356, 0.598 2.66
AKR/J f 0.282 0.0597   8 0.0211 0.212 0.173, 0.386 -0.21
AKR/J m 0.252 0.0263   8 0.00929 0.104 0.223, 0.29 -0.6
BALB/cByJ f 0.244 0.044   8 0.0156 0.181 0.176, 0.328 -0.73
BALB/cByJ m 0.212 0.036   8 0.0127 0.17 0.175, 0.288 -1.16
BALB/cJ f 0.206 0.0266   10 0.0084 0.129 0.182, 0.263 -1.26
BALB/cJ m 0.197 0.0214   10 0.00678 0.109 0.165, 0.244 -1.37
BTBR T+ Itpr3tf/J f 0.374 0.0811   8 0.0287 0.217 0.201, 0.458 1.07
BTBR T+ Itpr3tf/J m 0.323 0.0943   8 0.0333 0.292 0.244, 0.535 0.4
BUB/BnJ f 0.34 0.162   7 0.0612 0.477 0.196, 0.69 0.6
BUB/BnJ m 0.419 0.116   8 0.041 0.277 0.256, 0.637 1.75
C3H/HeJ f 0.359 0.0708   8 0.025 0.197 0.269, 0.463 0.86
C3H/HeJ m 0.384 0.123   8 0.0435 0.321 0.224, 0.646 1.26
C57BL/10J f 0.217 0.0285   8 0.0101 0.131 0.186, 0.266 -1.11
C57BL/10J m 0.251 0.0448   7 0.0169 0.179 0.197, 0.317 -0.61
C57BL/6J f 0.229 0.0273   7 0.0103 0.119 0.193, 0.259 -0.94
C57BL/6J m 0.218 0.0252   13 0.007 0.116 0.178, 0.283 -1.08
C57BLKS/J f 0.232 0.0329   11 0.00991 0.142 0.182, 0.304 -0.9
C57BLKS/J m 0.253 0.0467   8 0.0165 0.184 0.195, 0.324 -0.58
C57BR/cdJ f 0.204 0.0285   6 0.0116 0.14 0.169, 0.244 -1.29
C57BR/cdJ m 0.233 0.0272   8 0.00962 0.117 0.19, 0.269 -0.86
C57L/J f 0.223 0.0203   8 0.00719 0.0914 0.202, 0.262 -1.02
C57L/J m 0.24 0.0232   8 0.00821 0.0967 0.213, 0.289 -0.77
CBA/J f 0.241 0.0287   8 0.0101 0.119 0.207, 0.296 -0.77
CBA/J m 0.232 0.022   8 0.00777 0.0946 0.21, 0.274 -0.88
CE/J f 0.268 0.0487   8 0.0172 0.182 0.204, 0.343 -0.4
CE/J m 0.301 0.0578   9 0.0193 0.192 0.213, 0.388 0.09
DBA/1J f 0.295 0.0498   10 0.0157 0.169 0.201, 0.351 -0.03
DBA/1J m 0.389 0.0604   8 0.0214 0.155 0.303, 0.492 1.33
DBA/2J f 0.265 0.0467   8 0.0165 0.176 0.185, 0.307 -0.44
DBA/2J m 0.272 0.033   10 0.0104 0.121 0.209, 0.326 -0.32
FVB/NJ f 0.287 0.0563   8 0.0199 0.196 0.228, 0.394 -0.14
FVB/NJ m 0.221 0.0204   7 0.00771 0.0925 0.187, 0.245 -1.03
I/LnJ f 0.349 0.153   7 0.0577 0.437 0.226, 0.655 0.72
I/LnJ m 0.348 0.159   5 0.071 0.457 0.239, 0.606 0.75
KK/HlJ f 0.291 0.0775   8 0.0274 0.266 0.226, 0.456 -0.08
KK/HlJ m 0.302 0.0491   6 0.0201 0.163 0.233, 0.377 0.11
LP/J f 0.387 0.151   8 0.0535 0.391 0.241, 0.686 1.25
LP/J m 0.264 0.0504   8 0.0178 0.191 0.188, 0.326 -0.43
NOD/ShiLtJ f 0.227 0.0295   8 0.0104 0.13 0.177, 0.271 -0.97
NOD/ShiLtJ m 0.217 0.0352   8 0.0124 0.162 0.174, 0.267 -1.09
NON/ShiLtJ f 0.457 0.111   8 0.0393 0.243 0.307, 0.644 2.22
NON/ShiLtJ m 0.372 0.0668   8 0.0236 0.18 0.289, 0.494 1.09
NZW/LacJ f 0.327 0.0686   8 0.0243 0.21 0.261, 0.475 0.42
NZW/LacJ m 0.308 0.0825   8 0.0292 0.268 0.224, 0.476 0.19
PL/J f 0.41 0.09   8 0.0318 0.219 0.294, 0.546 1.57
PL/J m 0.382 0.0611   8 0.0216 0.16 0.246, 0.439 1.23
RIIIS/J f 0.247 0.0338   8 0.0119 0.137 0.181, 0.28 -0.69
RIIIS/J m 0.27 0.0335   8 0.0118 0.124 0.228, 0.318 -0.34
SJL/J f 0.32 0.0623   8 0.022 0.195 0.22, 0.404 0.32
SJL/J m 0.295 0.0411   8 0.0145 0.139 0.24, 0.36 0.01
SM/J f 0.224 0.017   8 0.00602 0.0762 0.192, 0.246 -1.01
SM/J m 0.265 0.078   8 0.0276 0.294 0.201, 0.403 -0.41
SWR/J f 0.379 0.0929   8 0.0329 0.245 0.254, 0.488 1.14
SWR/J m 0.349 0.0555   9 0.0185 0.159 0.27, 0.46 0.77


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2931 0.0245 0.3412 0.245
129S1/SvImJ m 0.2856 0.0245 0.3337 0.2375
A/J f 0.4325 0.0245 0.4806 0.3844
A/J m 0.483 0.0245 0.5311 0.4349
AKR/J f 0.2818 0.0245 0.3298 0.2337
AKR/J m 0.252 0.0245 0.3001 0.2039
BALB/cByJ f 0.244 0.0245 0.2921 0.1959
BALB/cByJ m 0.2115 0.0245 0.2596 0.1634
BALB/cJ f 0.2058 0.0219 0.2488 0.1628
BALB/cJ m 0.1969 0.0219 0.2399 0.1539
BTBR T+ Itpr3tf/J f 0.3736 0.0245 0.4217 0.3255
BTBR T+ Itpr3tf/J m 0.3228 0.0245 0.3708 0.2747
BUB/BnJ f 0.3396 0.0262 0.391 0.2882
BUB/BnJ m 0.4186 0.0245 0.4667 0.3705
C3H/HeJ f 0.3591 0.0245 0.4072 0.311
C3H/HeJ m 0.3836 0.0245 0.4317 0.3355
C57BL/10J f 0.2169 0.0245 0.265 0.1688
C57BL/10J m 0.2507 0.0262 0.3021 0.1993
C57BL/6J f 0.2293 0.0262 0.2807 0.1779
C57BL/6J m 0.2181 0.0192 0.2558 0.1803
C57BLKS/J f 0.2315 0.0209 0.2726 0.1905
C57BLKS/J m 0.2529 0.0245 0.301 0.2048
C57BR/cdJ f 0.2042 0.0283 0.2597 0.1486
C57BR/cdJ m 0.2332 0.0245 0.2813 0.1852
C57L/J f 0.2225 0.0245 0.2706 0.1744
C57L/J m 0.2401 0.0245 0.2882 0.192
CBA/J f 0.2415 0.0245 0.2896 0.1934
CBA/J m 0.2323 0.0245 0.2803 0.1842
CE/J f 0.2676 0.0245 0.3157 0.2195
CE/J m 0.3009 0.0231 0.3462 0.2555
DBA/1J f 0.295 0.0219 0.338 0.252
DBA/1J m 0.3891 0.0245 0.4372 0.341
DBA/2J f 0.2645 0.0245 0.3126 0.2164
DBA/2J m 0.2719 0.0219 0.3149 0.2289
FVB/NJ f 0.2871 0.0245 0.3352 0.239
FVB/NJ m 0.2206 0.0262 0.272 0.1692
I/LnJ f 0.3493 0.0262 0.4007 0.2979
I/LnJ m 0.3478 0.031 0.4086 0.287
KK/HlJ f 0.2912 0.0245 0.3393 0.2432
KK/HlJ m 0.3018 0.0283 0.3574 0.2463
LP/J f 0.3874 0.0245 0.4355 0.3393
LP/J m 0.2639 0.0245 0.312 0.2158
NOD/ShiLtJ f 0.2272 0.0245 0.2753 0.1792
NOD/ShiLtJ m 0.2172 0.0245 0.2653 0.1692
NON/ShiLtJ f 0.457 0.0245 0.5051 0.4089
NON/ShiLtJ m 0.3719 0.0245 0.42 0.3238
NZW/LacJ f 0.3274 0.0245 0.3755 0.2793
NZW/LacJ m 0.3079 0.0245 0.356 0.2598
PL/J f 0.4105 0.0245 0.4586 0.3624
PL/J m 0.3816 0.0245 0.4297 0.3335
RIIIS/J f 0.2469 0.0245 0.295 0.1988
RIIIS/J m 0.2702 0.0245 0.3183 0.2222
SJL/J f 0.3201 0.0245 0.3682 0.272
SJL/J m 0.2947 0.0245 0.3428 0.2467
SM/J f 0.2235 0.0245 0.2716 0.1754
SM/J m 0.2652 0.0245 0.3133 0.2172
SWR/J f 0.3794 0.0245 0.4275 0.3313
SWR/J m 0.3494 0.0231 0.3948 0.3041


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.2894 0.0173 0.3234 0.2554
A/J both 0.4577 0.0173 0.4918 0.4237
AKR/J both 0.2669 0.0173 0.3009 0.2329
BALB/cByJ both 0.2277 0.0173 0.2618 0.1937
BALB/cJ both 0.2013 0.0155 0.2318 0.1709
BTBR T+ Itpr3tf/J both 0.3482 0.0173 0.3822 0.3142
BUB/BnJ both 0.3791 0.0179 0.4143 0.3439
C3H/HeJ both 0.3714 0.0173 0.4054 0.3374
C57BL/10J both 0.2338 0.0179 0.269 0.1986
C57BL/6J both 0.2237 0.0162 0.2556 0.1918
C57BLKS/J both 0.2422 0.0161 0.2738 0.2106
C57BR/cdJ both 0.2187 0.0187 0.2554 0.182
C57L/J both 0.2313 0.0173 0.2653 0.1973
CBA/J both 0.2369 0.0173 0.2709 0.2029
CE/J both 0.2843 0.0168 0.3173 0.2512
DBA/1J both 0.3421 0.0164 0.3743 0.3098
DBA/2J both 0.2682 0.0164 0.3005 0.2359
FVB/NJ both 0.2538 0.0179 0.2891 0.2186
I/LnJ both 0.3485 0.0203 0.3884 0.3087
KK/HlJ both 0.2965 0.0187 0.3333 0.2598
LP/J both 0.3256 0.0173 0.3596 0.2916
NOD/ShiLtJ both 0.2222 0.0173 0.2563 0.1882
NON/ShiLtJ both 0.4144 0.0173 0.4484 0.3804
NZW/LacJ both 0.3176 0.0173 0.3516 0.2836
PL/J both 0.3961 0.0173 0.4301 0.3621
RIIIS/J both 0.2586 0.0173 0.2926 0.2246
SJL/J both 0.3074 0.0173 0.3414 0.2734
SM/J both 0.2444 0.0173 0.2784 0.2104
SWR/J both 0.3644 0.0168 0.3975 0.3314




  GWAS USING LINEAR MIXED MODELS