Project measure / variable:   Maurer1   ST_iso10

ID, description, units MPD:33252   ST_iso10   interval ST   [ms]  isoprot 10mg  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - interval ST isoprot 10mg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means39.2   ms
Median of the strain means39.5   ms
SD of the strain means± 5.57
Coefficient of variation (CV)0.142
Min–max range of strain means26.6   –   49.0   ms
Mean sample size per strain9.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 6308.5717 286.7533 3.6838 < 0.0001
Residuals 199 15490.488 77.8416


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 39.6 6.07   12 1.75 0.153 27.7, 48.0 0.07
A/J m 43.1 7.7   10 2.43 0.179 28.1, 51.5 0.7
AKR/J m 47.2 9.22   9 3.07 0.195 35.1, 64.0 1.43
BALB/cByJ m 39.3 11.3   9 3.77 0.288 11.0, 50.5 0.02
BALB/cJ m 42.5 19.9   8 7.04 0.468 13.7, 70.5 0.59
BTBR T+ Itpr3tf/J m 49.0 6.69   8 2.37 0.136 42.4, 62.4 1.76
C3H/HeJ m 32.3 7.05   9 2.35 0.218 20.0, 41.0 -1.24
C3H/HeOuJ m 39.5 6.74   11 2.03 0.171 30.4, 52.0 0.05
C57BL/6J m 33.4 5.67   8 2.01 0.17 26.1, 40.5 -1.04
C57BLKS/J m 43.0 9.53   10 3.01 0.222 32.6, 61.2 0.68
C58/J m 36.0 7.64   12 2.21 0.212 22.7, 50.5 -0.58
CBA/J m 34.9 4.87   10 1.54 0.139 26.8, 43.0 -0.77
DBA/2J m 40.1 12.2   7 4.62 0.304 25.2, 58.1 0.16
FVB/NJ m 38.2 7.46   13 2.07 0.195 27.0, 53.8 -0.18
I/LnJ m 44.4 10.7   10 3.39 0.242 28.8, 61.0 0.93
KK/HlJ m 46.7 7.79   10 2.46 0.167 37.2, 61.7 1.34
LP/J m 40.3 8.23   8 2.91 0.204 29.1, 51.4 0.2
NOD/ShiLtJ m 36.2 1.4   10 0.443 0.0388 33.8, 38.8 -0.54
NZB/BlNJ m 31.0 6.77   7 2.56 0.218 24.6, 43.3 -1.47
PL/J m 38.7 12.2   10 3.86 0.316 21.1, 63.6 -0.09
SJL/J m 26.6 2.05   10 0.649 0.0771 23.2, 30.0 -2.26
SM/J m 44.9 5.87   12 1.69 0.131 35.3, 53.3 1.02
SWR/J m 34.9 12.9   9 4.31 0.371 18.1, 61.9 -0.77


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 39.5833 2.5469 44.6057 34.5609
A/J m 43.12 2.79 48.6218 37.6182
AKR/J m 47.2444 2.9409 53.0438 41.4451
BALB/cByJ m 39.3 2.9409 45.0994 33.5006
BALB/cJ m 42.5125 3.1193 48.6637 36.3613
BTBR T+ Itpr3tf/J m 49.025 3.1193 55.1762 42.8738
C3H/HeJ m 32.3222 2.9409 38.1216 26.5228
C3H/HeOuJ m 39.5455 2.6602 44.7912 34.2997
C57BL/6J m 33.3875 3.1193 39.5387 27.2363
C57BLKS/J m 43.01 2.79 48.5118 37.5082
C58/J m 35.9667 2.5469 40.9891 30.9443
CBA/J m 34.91 2.79 40.4118 29.4082
DBA/2J m 40.1429 3.3347 46.7187 33.567
FVB/NJ m 38.2462 2.447 43.0715 33.4208
I/LnJ m 44.37 2.79 49.8718 38.8682
KK/HlJ m 46.67 2.79 52.1718 41.1682
LP/J m 40.275 3.1193 46.4262 34.1238
NOD/ShiLtJ m 36.17 2.79 41.6718 30.6682
NZB/BlNJ m 30.9714 3.3347 37.5473 24.3955
PL/J m 38.68 2.79 44.1818 33.1782
SJL/J m 26.64 2.79 32.1418 21.1382
SM/J m 44.9083 2.5469 49.9307 39.8859
SWR/J m 34.8556 2.9409 40.6549 29.0562




  GWAS USING LINEAR MIXED MODELS