Project measure / variable:   Maurer1   P_dur_ctrl

ID, description, units MPD:33229   P_dur_ctrl   duration P-wave   [ms]  control  
atenolol, isoproterenol study
Data set, strains Maurer1   inbred   23 strains     sex: m     age: 7-13wks
Procedure ECG
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  STRAIN COMPARISON PLOT
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Maurer1 - duration P-wave control



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested23 strains
Mean of the strain means11.8   ms
Median of the strain means11.6   ms
SD of the strain means± 0.989
Coefficient of variation (CV)0.0836
Min–max range of strain means10.0   –   14.2   ms
Mean sample size per strain9.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 22 209.3924 9.5178 4.1702 < 0.0001
Residuals 202 461.0306 2.2823


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 12.3 1.14   13 0.316 0.0923 10.0, 14.0 0.47
A/J m 11.7 1.41   11 0.426 0.121 9.0, 14.0 -0.13
AKR/J m 13.6 1.24   8 0.437 0.0906 11.8, 15.1 1.79
BALB/cByJ m 12.8 1.56   9 0.52 0.122 11.0, 16.0 0.98
BALB/cJ m 12.6 1.9   10 0.599 0.15 10.2, 15.8 0.78
BTBR T+ Itpr3tf/J m 14.2 1.25   10 0.397 0.0887 13.0, 17.0 2.4
C3H/HeJ m 11.1 1.0   10 0.317 0.0906 9.0, 12.2 -0.74
C3H/HeOuJ m 11.9 1.49   9 0.497 0.126 10.0, 14.9 0.07
C57BL/6J m 11.5 0.987   9 0.329 0.0857 10.0, 13.0 -0.33
C57BLKS/J m 11.4 0.765   10 0.242 0.067 9.82, 12.2 -0.44
C58/J m 10.0 2.08   12 0.6 0.207 5.95, 11.9 -1.85
CBA/J m 11.6 1.42   8 0.502 0.123 10.0, 14.0 -0.23
DBA/2J m 12.4 2.24   6 0.914 0.181 8.68, 14.9 0.58
FVB/NJ m 11.2 0.563   12 0.163 0.0505 10.2, 12.0 -0.64
I/LnJ m 10.8 1.04   10 0.328 0.0959 8.97, 12.1 -1.04
KK/HlJ m 11.0 1.8   10 0.569 0.163 9.12, 13.9 -0.84
LP/J m 11.3 1.04   8 0.369 0.0928 10.0, 13.0 -0.54
NOD/ShiLtJ m 11.8 1.58   9 0.527 0.134 8.0, 13.0 -0.03
NZB/BlNJ m 13.2 1.57   8 0.555 0.119 11.0, 15.9 1.38
PL/J m 12.2 2.5   10 0.792 0.205 10.0, 17.9 0.37
SJL/J m 11.6 0.878   9 0.293 0.0759 9.98, 12.9 -0.23
SM/J m 11.4 1.97   14 0.526 0.172 9.0, 16.0 -0.44
SWR/J m 10.5 1.56   10 0.495 0.149 8.03, 12.8 -1.34


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 12.3462 0.419 13.1723 11.52
A/J m 11.6545 0.4555 12.5527 10.7564
AKR/J m 13.6375 0.5341 14.6907 12.5843
BALB/cByJ m 12.7556 0.5036 13.7485 11.7626
BALB/cJ m 12.64 0.4777 13.582 11.698
BTBR T+ Itpr3tf/J m 14.15 0.4777 15.092 13.208
C3H/HeJ m 11.06 0.4777 12.002 10.118
C3H/HeOuJ m 11.8778 0.5036 12.8707 10.8848
C57BL/6J m 11.5111 0.5036 12.5041 10.5182
C57BLKS/J m 11.422 0.4777 12.364 10.48
C58/J m 10.0292 0.4361 10.8891 9.1692
CBA/J m 11.5875 0.5341 12.6407 10.5343
DBA/2J m 12.38 0.6168 13.5961 11.1639
FVB/NJ m 11.15 0.4361 12.0099 10.2901
I/LnJ m 10.81 0.4777 11.752 9.868
KK/HlJ m 11.022 0.4777 11.964 10.08
LP/J m 11.2625 0.5341 12.3157 10.2093
NOD/ShiLtJ m 11.7556 0.5036 12.7485 10.7626
NZB/BlNJ m 13.1875 0.5341 14.2407 12.1343
PL/J m 12.2 0.4777 13.142 11.258
SJL/J m 11.5644 0.5036 12.5574 10.5715
SM/J m 11.4143 0.4038 12.2104 10.6182
SWR/J m 10.478 0.4777 11.42 9.536




  GWAS USING LINEAR MIXED MODELS